CYTH3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0032012Biological processregulation of ARF protein signal transduction
GO_0045785Biological processpositive regulation of cell adhesion
GO_0090162Biological processestablishment of epithelial cell polarity
GO_0048193Biological processGolgi vesicle transport
GO_0001726Cellular componentruffle
GO_0000139Cellular componentGolgi membrane
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005912Cellular componentadherens junction
GO_0005886Cellular componentplasma membrane
GO_0005923Cellular componentbicellular tight junction
GO_0005085Molecular functionguanyl-nucleotide exchange factor activity
GO_0005547Molecular functionphosphatidylinositol-3,4,5-trisphosphate binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCYTH3
Protein nameCYTH3 protein
Cytohesin-3 (ARF nucleotide-binding site opener 3) (Protein ARNO3) (General receptor of phosphoinositides 1) (Grp1) (PH, SEC7 and coiled-coil domain-containing protein 3)
SynonymsGRP1
PSCD3
ARNO3
DescriptionFUNCTION: Promotes guanine-nucleotide exchange on ARF1 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays a role in the epithelial polarization (By similarity). .

AccessionsO43739
Q96HS5
ENST00000350796.8 [O43739-2]