Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 20 studies | 50% ± 23% | |
astrocyte | 19 studies | 64% ± 26% | |
oligodendrocyte | 16 studies | 88% ± 17% | |
oligodendrocyte precursor cell | 15 studies | 79% ± 23% | |
fibroblast | 14 studies | 55% ± 16% | |
glutamatergic neuron | 13 studies | 84% ± 18% | |
microglial cell | 13 studies | 55% ± 21% | |
smooth muscle cell | 12 studies | 48% ± 22% | |
GABAergic neuron | 11 studies | 81% ± 18% | |
adipocyte | 9 studies | 48% ± 17% | |
amacrine cell | 8 studies | 56% ± 28% | |
pericyte | 8 studies | 38% ± 16% | |
endothelial cell of lymphatic vessel | 8 studies | 45% ± 16% | |
neuron | 7 studies | 59% ± 17% | |
retinal cone cell | 7 studies | 70% ± 33% | |
mesothelial cell | 7 studies | 47% ± 16% | |
macrophage | 6 studies | 31% ± 19% | |
interneuron | 6 studies | 75% ± 28% | |
cardiac muscle cell | 6 studies | 75% ± 17% | |
retinal bipolar neuron | 5 studies | 69% ± 23% | |
epithelial cell | 5 studies | 38% ± 17% | |
ON-bipolar cell | 5 studies | 63% ± 34% | |
type I pneumocyte | 5 studies | 28% ± 9% | |
type II pneumocyte | 5 studies | 78% ± 12% | |
hepatocyte | 4 studies | 54% ± 26% | |
glial cell | 4 studies | 47% ± 22% | |
granule cell | 4 studies | 77% ± 18% | |
Mueller cell | 4 studies | 53% ± 23% | |
OFF-bipolar cell | 4 studies | 55% ± 27% | |
retinal rod cell | 4 studies | 72% ± 15% | |
hepatic stellate cell | 3 studies | 46% ± 13% | |
differentiation-committed oligodendrocyte precursor | 3 studies | 74% ± 12% | |
GABAergic interneuron | 3 studies | 93% ± 7% | |
Purkinje cell | 3 studies | 70% ± 23% | |
progenitor cell | 3 studies | 51% ± 6% | |
vein endothelial cell | 3 studies | 22% ± 6% | |
GABAergic amacrine cell | 3 studies | 88% ± 5% | |
glycinergic amacrine cell | 3 studies | 82% ± 5% | |
retina horizontal cell | 3 studies | 65% ± 15% | |
retinal ganglion cell | 3 studies | 77% ± 12% | |
rod bipolar cell | 3 studies | 92% ± 12% | |
endothelial cell of vascular tree | 3 studies | 25% ± 1% | |
retinal pigment epithelial cell | 3 studies | 53% ± 17% | |
ependymal cell | 3 studies | 53% ± 17% | |
ciliated cell | 3 studies | 26% ± 3% | |
club cell | 3 studies | 25% ± 1% | |
myofibroblast cell | 3 studies | 45% ± 22% | |
muscle cell | 3 studies | 45% ± 22% | |
mast cell | 3 studies | 29% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 8965.28 | 2640 / 2642 | 98% | 11.88 | 692 / 705 |
adrenal gland | 96% | 3186.44 | 248 / 258 | 70% | 6.90 | 161 / 230 |
thymus | 88% | 1363.16 | 577 / 653 | 48% | 1.82 | 288 / 605 |
prostate | 29% | 237.17 | 70 / 245 | 84% | 2.39 | 424 / 502 |
ovary | 78% | 889.89 | 140 / 180 | 1% | 0.03 | 6 / 430 |
skin | 70% | 2054.27 | 1262 / 1809 | 3% | 0.09 | 16 / 472 |
esophagus | 57% | 568.45 | 823 / 1445 | 7% | 0.11 | 12 / 183 |
uterus | 32% | 276.91 | 55 / 170 | 11% | 0.24 | 49 / 459 |
intestine | 36% | 336.09 | 351 / 966 | 4% | 0.07 | 21 / 527 |
blood vessel | 39% | 475.77 | 525 / 1335 | 0% | 0 | 0 / 0 |
bladder | 29% | 238.14 | 6 / 21 | 5% | 0.19 | 26 / 504 |
lung | 7% | 90.48 | 40 / 578 | 24% | 0.47 | 278 / 1155 |
pancreas | 2% | 13.34 | 6 / 328 | 28% | 0.54 | 49 / 178 |
stomach | 20% | 216.99 | 73 / 359 | 5% | 0.12 | 15 / 286 |
kidney | 10% | 99.27 | 9 / 89 | 14% | 0.41 | 128 / 901 |
breast | 3% | 29.44 | 16 / 459 | 14% | 0.28 | 156 / 1118 |
adipose | 14% | 140.25 | 172 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 10% | 0.57 | 3 / 29 |
heart | 9% | 77.39 | 81 / 861 | 0% | 0 | 0 / 0 |
liver | 5% | 44.66 | 12 / 226 | 3% | 0.06 | 12 / 406 |
tonsil | 0% | 0 | 0 / 0 | 4% | 0.07 | 2 / 45 |
spleen | 4% | 30.46 | 10 / 241 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 3% | 0.08 | 2 / 80 |
muscle | 0% | 3.94 | 4 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0009790 | Biological process | embryo development |
GO_0046037 | Biological process | GMP metabolic process |
GO_0035865 | Biological process | cellular response to potassium ion |
GO_0097120 | Biological process | receptor localization to synapse |
GO_0046710 | Biological process | GDP metabolic process |
GO_0099072 | Biological process | regulation of postsynaptic membrane neurotransmitter receptor levels |
GO_0043113 | Biological process | receptor clustering |
GO_0099641 | Biological process | anterograde axonal protein transport |
GO_0007268 | Biological process | chemical synaptic transmission |
GO_0099642 | Biological process | retrograde axonal protein transport |
GO_0098609 | Biological process | cell-cell adhesion |
GO_0045197 | Biological process | establishment or maintenance of epithelial cell apical/basal polarity |
GO_0098839 | Cellular component | postsynaptic density membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0031594 | Cellular component | neuromuscular junction |
GO_0016020 | Cellular component | membrane |
GO_0043204 | Cellular component | perikaryon |
GO_0043005 | Cellular component | neuron projection |
GO_0005829 | Cellular component | cytosol |
GO_0005912 | Cellular component | adherens junction |
GO_0014069 | Cellular component | postsynaptic density |
GO_0044224 | Cellular component | juxtaparanode region of axon |
GO_0008076 | Cellular component | voltage-gated potassium channel complex |
GO_1904115 | Cellular component | axon cytoplasm |
GO_0016323 | Cellular component | basolateral plasma membrane |
GO_0019900 | Molecular function | kinase binding |
GO_0019901 | Molecular function | protein kinase binding |
GO_0004385 | Molecular function | guanylate kinase activity |
GO_0035255 | Molecular function | ionotropic glutamate receptor binding |
GO_0005515 | Molecular function | protein binding |
Gene name | DLG2 |
Protein name | Discs large 2 isoform A Discs large MAGUK scaffold protein 2 (cDNA FLJ54724, highly similar to Discs large homolog 2) DLG2 protein isoform Alternative protein DLG2 Discs large MAGUK scaffold protein 2 (cDNA FLJ60066, highly similar to Discs large homolog 2) Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93) Discs large MAGUK scaffold protein 2 |
Synonyms | |
Description | FUNCTION: Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity). . |
Accessions | A0A3B3ITF1 ENST00000527088.2 A0A994J570 E9PPV7 ENST00000404783.7 ENST00000426717.6 [Q15700-5] A0A3B3ITF4 E9PIJ9 ENST00000530800.5 ENST00000529399.1 ENST00000457267.5 A0A994J7X6 ENST00000706206.1 A8MUT9 ENST00000524601.5 ENST00000706243.1 ENST00000398304.5 B7Z2T4 ENST00000376104.7 [Q15700-2] A0A240F9Y2 A8MVA8 ENST00000524982.5 E9PRX3 ENST00000706203.1 ENST00000529401.5 F8W750 ENST00000420775.6 A0A994J822 ENST00000418306.6 [Q15700-3] ENST00000472545.6 A0A994J5A4 A0A994J7Q5 ENST00000706007.1 ENST00000706226.1 H7C325 A0A994J5G4 F8VYC1 B5MCC5 ENST00000434967.1 ENST00000706204.1 A0A3B3ISW2 ENST00000531015.5 A0A994J5T6 A0A994J819 C9JFF9 A0A994J7N9 ENST00000398299.1 E9PIW2 A0A240F9Y1 A0A994J7P1 ENST00000330014.11 E9PN83 X5DRL5 ENST00000706266.1 ENST00000280241.12 [Q15700-4] ENST00000650630.1 A0A5F9ZH92 A0A994J587 ENST00000706233.1 ENST00000706006.1 E9PRL2 ENST00000706267.1 ENST00000648622.1 E9PQT9 Q15700 ENST00000398309.6 [Q15700-1] ENST00000706232.1 L8E8R0 ENST00000532653.5 ENST00000527466.2 |