DLG2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0009790Biological processembryo development
GO_0046037Biological processGMP metabolic process
GO_0035865Biological processcellular response to potassium ion
GO_0097120Biological processreceptor localization to synapse
GO_0046710Biological processGDP metabolic process
GO_0099072Biological processregulation of postsynaptic membrane neurotransmitter receptor levels
GO_0043113Biological processreceptor clustering
GO_0099641Biological processanterograde axonal protein transport
GO_0007268Biological processchemical synaptic transmission
GO_0099642Biological processretrograde axonal protein transport
GO_0098609Biological processcell-cell adhesion
GO_0045197Biological processestablishment or maintenance of epithelial cell apical/basal polarity
GO_0098839Cellular componentpostsynaptic density membrane
GO_0005886Cellular componentplasma membrane
GO_0031594Cellular componentneuromuscular junction
GO_0016020Cellular componentmembrane
GO_0043204Cellular componentperikaryon
GO_0043005Cellular componentneuron projection
GO_0005829Cellular componentcytosol
GO_0005912Cellular componentadherens junction
GO_0014069Cellular componentpostsynaptic density
GO_0044224Cellular componentjuxtaparanode region of axon
GO_0008076Cellular componentvoltage-gated potassium channel complex
GO_1904115Cellular componentaxon cytoplasm
GO_0016323Cellular componentbasolateral plasma membrane
GO_0019900Molecular functionkinase binding
GO_0019901Molecular functionprotein kinase binding
GO_0004385Molecular functionguanylate kinase activity
GO_0035255Molecular functionionotropic glutamate receptor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameDLG2
Protein nameDiscs large 2 isoform A
Discs large MAGUK scaffold protein 2 (cDNA FLJ54724, highly similar to Discs large homolog 2)
DLG2 protein isoform
Alternative protein DLG2
Discs large MAGUK scaffold protein 2 (cDNA FLJ60066, highly similar to Discs large homolog 2)
Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)
Discs large MAGUK scaffold protein 2
Synonyms
DescriptionFUNCTION: Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity). .

AccessionsA0A3B3ITF1
ENST00000527088.2
A0A994J570
E9PPV7
ENST00000404783.7
ENST00000426717.6 [Q15700-5]
A0A3B3ITF4
E9PIJ9
ENST00000530800.5
ENST00000529399.1
ENST00000457267.5
A0A994J7X6
ENST00000706206.1
A8MUT9
ENST00000524601.5
ENST00000706243.1
ENST00000398304.5
B7Z2T4
ENST00000376104.7 [Q15700-2]
A0A240F9Y2
A8MVA8
ENST00000524982.5
E9PRX3
ENST00000706203.1
ENST00000529401.5
F8W750
ENST00000420775.6
A0A994J822
ENST00000418306.6 [Q15700-3]
ENST00000472545.6
A0A994J5A4
A0A994J7Q5
ENST00000706007.1
ENST00000706226.1
H7C325
A0A994J5G4
F8VYC1
B5MCC5
ENST00000434967.1
ENST00000706204.1
A0A3B3ISW2
ENST00000531015.5
A0A994J5T6
A0A994J819
C9JFF9
A0A994J7N9
ENST00000398299.1
E9PIW2
A0A240F9Y1
A0A994J7P1
ENST00000330014.11
E9PN83
X5DRL5
ENST00000706266.1
ENST00000280241.12 [Q15700-4]
ENST00000650630.1
A0A5F9ZH92
A0A994J587
ENST00000706233.1
ENST00000706006.1
E9PRL2
ENST00000706267.1
ENST00000648622.1
E9PQT9
Q15700
ENST00000398309.6 [Q15700-1]
ENST00000706232.1
L8E8R0
ENST00000532653.5
ENST00000527466.2