Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| pericyte | 26 studies | 32% ± 13% | |
| smooth muscle cell | 15 studies | 29% ± 9% | |
| epithelial cell of proximal tubule | 5 studies | 28% ± 11% | |
| endothelial cell | 5 studies | 31% ± 12% | |
| glutamatergic neuron | 5 studies | 28% ± 9% | |
| oligodendrocyte precursor cell | 4 studies | 26% ± 11% | |
| neuron | 3 studies | 39% ± 16% | |
| GABAergic neuron | 3 studies | 20% ± 4% |
Insufficient scRNA-seq data for expression of CDH6 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| kidney | 100% | 4939.09 | 89 / 89 | 89% | 87.81 | 798 / 901 |
| thymus | 98% | 667.12 | 641 / 653 | 67% | 11.61 | 404 / 605 |
| brain | 88% | 747.32 | 2334 / 2642 | 54% | 5.43 | 379 / 705 |
| ovary | 38% | 172.56 | 69 / 180 | 88% | 42.79 | 378 / 430 |
| uterus | 96% | 618.21 | 163 / 170 | 17% | 3.68 | 76 / 459 |
| lung | 100% | 1267.85 | 577 / 578 | 10% | 1.83 | 120 / 1155 |
| esophagus | 87% | 486.09 | 1264 / 1445 | 19% | 1.68 | 35 / 183 |
| breast | 97% | 732.50 | 447 / 459 | 6% | 0.30 | 63 / 1118 |
| bladder | 95% | 586.10 | 20 / 21 | 4% | 0.32 | 20 / 504 |
| adipose | 99% | 1074.11 | 1191 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 93% | 1912.42 | 1245 / 1335 | 0% | 0 | 0 / 0 |
| prostate | 85% | 432.73 | 208 / 245 | 0% | 0.02 | 2 / 502 |
| intestine | 76% | 366.33 | 733 / 966 | 8% | 0.49 | 40 / 527 |
| stomach | 64% | 224.23 | 229 / 359 | 12% | 1.29 | 34 / 286 |
| heart | 66% | 223.34 | 571 / 861 | 0% | 0 | 0 / 0 |
| pancreas | 15% | 56.95 | 48 / 328 | 43% | 3.89 | 76 / 178 |
| muscle | 48% | 136.83 | 389 / 803 | 0% | 0 | 0 / 0 |
| skin | 38% | 138.36 | 694 / 1809 | 5% | 1.16 | 24 / 472 |
| adrenal gland | 7% | 20.02 | 19 / 258 | 18% | 1.64 | 42 / 230 |
| liver | 7% | 23.05 | 16 / 226 | 17% | 5.55 | 71 / 406 |
| spleen | 23% | 61.22 | 56 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.10 | 1 / 45 |
| peripheral blood | 1% | 2.50 | 5 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007043 | Biological process | cell-cell junction assembly |
| GO_0034332 | Biological process | adherens junction organization |
| GO_0007219 | Biological process | Notch signaling pathway |
| GO_0007275 | Biological process | multicellular organism development |
| GO_0099560 | Biological process | synaptic membrane adhesion |
| GO_0007155 | Biological process | cell adhesion |
| GO_0044331 | Biological process | cell-cell adhesion mediated by cadherin |
| GO_0007156 | Biological process | homophilic cell adhesion via plasma membrane adhesion molecules |
| GO_0016339 | Biological process | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules |
| GO_0000902 | Biological process | cell morphogenesis |
| GO_0016477 | Biological process | cell migration |
| GO_0098978 | Cellular component | glutamatergic synapse |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0016342 | Cellular component | catenin complex |
| GO_0005912 | Cellular component | adherens junction |
| GO_0030054 | Cellular component | cell junction |
| GO_0045296 | Molecular function | cadherin binding |
| GO_0008013 | Molecular function | beta-catenin binding |
| GO_0005509 | Molecular function | calcium ion binding |
| Gene name | CDH6 |
| Protein name | Cadherin 6 Alternative protein CDH6 Cadherin-6 (Kidney cadherin) (K-cadherin) |
| Synonyms | |
| Description | FUNCTION: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. |
| Accessions | ENST00000265071.3 [P55285-1] ENST00000514738.5 P55285 L8EAC6 D6RF86 |