SORBS1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0031589Biological processcell-substrate adhesion
GO_0046326Biological processpositive regulation of glucose import
GO_0032869Biological processcellular response to insulin stimulus
GO_0007160Biological processcell-matrix adhesion
GO_0046889Biological processpositive regulation of lipid biosynthetic process
GO_0045725Biological processpositive regulation of glycogen biosynthetic process
GO_1903078Biological processpositive regulation of protein localization to plasma membrane
GO_0008286Biological processinsulin receptor signaling pathway
GO_0046628Biological processpositive regulation of insulin receptor signaling pathway
GO_0048041Biological processfocal adhesion assembly
GO_0043149Biological processstress fiber assembly
GO_0030055Cellular componentcell-substrate junction
GO_0005915Cellular componentzonula adherens
GO_0005886Cellular componentplasma membrane
GO_0045121Cellular componentmembrane raft
GO_0005813Cellular componentcentrosome
GO_0016600Cellular componentflotillin complex
GO_0005925Cellular componentfocal adhesion
GO_0016363Cellular componentnuclear matrix
GO_0001725Cellular componentstress fiber
GO_0005829Cellular componentcytosol
GO_0005912Cellular componentadherens junction
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0005158Molecular functioninsulin receptor binding
GO_0030159Molecular functionsignaling receptor complex adaptor activity
GO_0008092Molecular functioncytoskeletal protein binding
GO_0005515Molecular functionprotein binding
GO_0003779Molecular functionactin binding

IV. Literature review

[source]
Gene nameSORBS1
Protein nameSorbin and SH3 domain containing 1
Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)
SynonymsSH3D5
KIAA1296
KIAA0894
DescriptionFUNCTION: Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions (By similarity). .

AccessionsENST00000634504.1
ENST00000371246.6 [Q9BX66-2]
A0A0U1RQI5
ENST00000647619.2
S4R303
S4R406
ENST00000607232.5 [Q9BX66-12]
ENST00000649575.2
ENST00000371239.5 [Q9BX66-8]
ENST00000649911.2
Q5T925
ENST00000486141.3
ENST00000371228.2
A0A3B3IRW8
ENST00000371245.7 [Q9BX66-3]
ENST00000354106.7 [Q9BX66-5]
ENST00000371249.6 [Q9BX66-10]
ENST00000371247.7 [Q9BX66-1]
ENST00000277982.9 [Q9BX66-2]
ENST00000492542.1
ENST00000361941.7 [Q9BX66-1]
A0A3B3IT56
Q9BX66
ENST00000306402.10 [Q9BX66-9]
ENST00000371227.8 [Q9BX66-11]
A0A3B3IRR9
ENST00000371241.5 [Q9BX66-4]