Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 26 studies | 50% ± 20% | |
smooth muscle cell | 25 studies | 42% ± 17% | |
astrocyte | 20 studies | 73% ± 19% | |
oligodendrocyte precursor cell | 14 studies | 41% ± 18% | |
glutamatergic neuron | 13 studies | 62% ± 24% | |
GABAergic neuron | 11 studies | 61% ± 23% | |
adipocyte | 9 studies | 82% ± 11% | |
fibroblast | 8 studies | 42% ± 19% | |
neuron | 7 studies | 44% ± 17% | |
pericyte | 7 studies | 37% ± 18% | |
mast cell | 7 studies | 29% ± 12% | |
myofibroblast cell | 6 studies | 33% ± 27% | |
interneuron | 6 studies | 63% ± 17% | |
retinal ganglion cell | 6 studies | 45% ± 23% | |
capillary endothelial cell | 6 studies | 41% ± 20% | |
cardiac muscle cell | 6 studies | 84% ± 15% | |
endothelial cell of lymphatic vessel | 5 studies | 27% ± 6% | |
type I pneumocyte | 5 studies | 30% ± 3% | |
type II pneumocyte | 5 studies | 31% ± 6% | |
hepatocyte | 4 studies | 62% ± 29% | |
granule cell | 4 studies | 52% ± 6% | |
Mueller cell | 4 studies | 47% ± 16% | |
endothelial cell of vascular tree | 4 studies | 25% ± 1% | |
muscle cell | 4 studies | 54% ± 25% | |
oligodendrocyte | 4 studies | 32% ± 16% | |
endothelial cell of sinusoid | 3 studies | 31% ± 12% | |
hepatic stellate cell | 3 studies | 59% ± 10% | |
GABAergic interneuron | 3 studies | 69% ± 1% | |
Purkinje cell | 3 studies | 70% ± 22% | |
epithelial cell | 3 studies | 32% ± 13% | |
microglial cell | 3 studies | 44% ± 16% | |
endothelial cell of artery | 3 studies | 21% ± 6% | |
vein endothelial cell | 3 studies | 26% ± 4% | |
GABAergic amacrine cell | 3 studies | 24% ± 4% | |
amacrine cell | 3 studies | 51% ± 19% | |
glycinergic amacrine cell | 3 studies | 37% ± 7% | |
cholangiocyte | 3 studies | 62% ± 14% | |
ependymal cell | 3 studies | 88% ± 6% | |
Schwann cell | 3 studies | 44% ± 16% | |
goblet cell | 3 studies | 29% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 82% | 12997.33 | 2158 / 2642 | 100% | 88.90 | 702 / 705 |
prostate | 84% | 30571.08 | 207 / 245 | 93% | 42.64 | 467 / 502 |
breast | 83% | 20688.47 | 381 / 459 | 81% | 18.04 | 909 / 1118 |
stomach | 75% | 36030.66 | 271 / 359 | 81% | 31.79 | 233 / 286 |
intestine | 77% | 53900.35 | 746 / 966 | 75% | 16.52 | 397 / 527 |
esophagus | 82% | 66863.90 | 1188 / 1445 | 67% | 21.99 | 123 / 183 |
bladder | 90% | 67193.10 | 19 / 21 | 43% | 11.48 | 218 / 504 |
uterus | 90% | 35417.35 | 153 / 170 | 28% | 12.57 | 129 / 459 |
liver | 21% | 2310.20 | 48 / 226 | 80% | 12.66 | 324 / 406 |
lung | 57% | 7547.15 | 331 / 578 | 43% | 11.43 | 499 / 1155 |
skin | 15% | 1851.85 | 276 / 1809 | 85% | 25.47 | 402 / 472 |
eye | 0% | 0 | 0 / 0 | 100% | 104.54 | 80 / 80 |
blood vessel | 100% | 84423.14 | 1334 / 1335 | 0% | 0 | 0 / 0 |
muscle | 99% | 32734.79 | 792 / 803 | 0% | 0 | 0 / 0 |
kidney | 11% | 1285.79 | 10 / 89 | 85% | 22.28 | 765 / 901 |
adipose | 92% | 30283.32 | 1105 / 1204 | 0% | 0 | 0 / 0 |
heart | 91% | 35413.93 | 785 / 861 | 0% | 0 | 0 / 0 |
pancreas | 0% | 0 | 0 / 328 | 81% | 15.64 | 144 / 178 |
adrenal gland | 2% | 224.78 | 4 / 258 | 46% | 6.98 | 106 / 230 |
ovary | 12% | 3297.62 | 21 / 180 | 35% | 3.68 | 150 / 430 |
thymus | 9% | 1320.89 | 60 / 653 | 13% | 1.28 | 80 / 605 |
tonsil | 0% | 0 | 0 / 0 | 7% | 0.82 | 3 / 45 |
spleen | 1% | 109.60 | 2 / 241 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0031589 | Biological process | cell-substrate adhesion |
GO_0046326 | Biological process | positive regulation of glucose import |
GO_0032869 | Biological process | cellular response to insulin stimulus |
GO_0007160 | Biological process | cell-matrix adhesion |
GO_0046889 | Biological process | positive regulation of lipid biosynthetic process |
GO_0045725 | Biological process | positive regulation of glycogen biosynthetic process |
GO_1903078 | Biological process | positive regulation of protein localization to plasma membrane |
GO_0008286 | Biological process | insulin receptor signaling pathway |
GO_0046628 | Biological process | positive regulation of insulin receptor signaling pathway |
GO_0048041 | Biological process | focal adhesion assembly |
GO_0043149 | Biological process | stress fiber assembly |
GO_0030055 | Cellular component | cell-substrate junction |
GO_0005915 | Cellular component | zonula adherens |
GO_0005886 | Cellular component | plasma membrane |
GO_0045121 | Cellular component | membrane raft |
GO_0005813 | Cellular component | centrosome |
GO_0016600 | Cellular component | flotillin complex |
GO_0005925 | Cellular component | focal adhesion |
GO_0016363 | Cellular component | nuclear matrix |
GO_0001725 | Cellular component | stress fiber |
GO_0005829 | Cellular component | cytosol |
GO_0005912 | Cellular component | adherens junction |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0005158 | Molecular function | insulin receptor binding |
GO_0030159 | Molecular function | signaling receptor complex adaptor activity |
GO_0008092 | Molecular function | cytoskeletal protein binding |
GO_0005515 | Molecular function | protein binding |
GO_0003779 | Molecular function | actin binding |
Gene name | SORBS1 |
Protein name | Sorbin and SH3 domain containing 1 Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP) |
Synonyms | SH3D5 KIAA1296 KIAA0894 |
Description | FUNCTION: Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions (By similarity). . |
Accessions | ENST00000634504.1 ENST00000371246.6 [Q9BX66-2] A0A0U1RQI5 ENST00000647619.2 S4R303 S4R406 ENST00000607232.5 [Q9BX66-12] ENST00000649575.2 ENST00000371239.5 [Q9BX66-8] ENST00000649911.2 Q5T925 ENST00000486141.3 ENST00000371228.2 A0A3B3IRW8 ENST00000371245.7 [Q9BX66-3] ENST00000354106.7 [Q9BX66-5] ENST00000371249.6 [Q9BX66-10] ENST00000371247.7 [Q9BX66-1] ENST00000277982.9 [Q9BX66-2] ENST00000492542.1 ENST00000361941.7 [Q9BX66-1] A0A3B3IT56 Q9BX66 ENST00000306402.10 [Q9BX66-9] ENST00000371227.8 [Q9BX66-11] A0A3B3IRR9 ENST00000371241.5 [Q9BX66-4] |