TMOD3 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	43 studies	36% ± 13%	Explore
fibroblast	28 studies	26% ± 9%	Explore
macrophage	26 studies	26% ± 10%	Explore
natural killer cell	25 studies	24% ± 7%	Explore
mast cell	22 studies	30% ± 10%	Explore
classical monocyte	20 studies	25% ± 8%	Explore
CD8-positive, alpha-beta T cell	19 studies	22% ± 5%	Explore
endothelial cell of lymphatic vessel	18 studies	33% ± 10%	Explore
pericyte	18 studies	27% ± 11%	Explore
non-classical monocyte	18 studies	30% ± 11%	Explore
CD4-positive, alpha-beta T cell	17 studies	20% ± 6%	Explore
regulatory T cell	17 studies	23% ± 4%	Explore
ciliated cell	15 studies	30% ± 14%	Explore
capillary endothelial cell	15 studies	28% ± 5%	Explore
smooth muscle cell	14 studies	19% ± 4%	Explore
epithelial cell	14 studies	35% ± 20%	Explore
gamma-delta T cell	14 studies	25% ± 9%	Explore
T cell	13 studies	23% ± 6%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	25% ± 6%	Explore
vein endothelial cell	13 studies	31% ± 13%	Explore
type I pneumocyte	12 studies	50% ± 14%	Explore
basal cell	12 studies	33% ± 19%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	23% ± 4%	Explore
endothelial cell of artery	12 studies	30% ± 8%	Explore
endothelial cell of vascular tree	12 studies	29% ± 11%	Explore
B cell	11 studies	19% ± 3%	Explore
monocyte	11 studies	28% ± 8%	Explore
mucosal invariant T cell	11 studies	22% ± 4%	Explore
club cell	10 studies	26% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell	10 studies	22% ± 4%	Explore
dendritic cell	10 studies	25% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	24% ± 5%	Explore
secretory cell	9 studies	36% ± 13%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	9 studies	21% ± 3%	Explore
mature NK T cell	9 studies	24% ± 3%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	21% ± 5%	Explore
platelet	8 studies	26% ± 8%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	8 studies	21% ± 5%	Explore
myofibroblast cell	8 studies	19% ± 3%	Explore
myeloid cell	8 studies	31% ± 10%	Explore
respiratory goblet cell	7 studies	30% ± 8%	Explore
conventional dendritic cell	7 studies	29% ± 14%	Explore
alveolar macrophage	6 studies	28% ± 10%	Explore
microglial cell	6 studies	30% ± 10%	Explore
lymphocyte	6 studies	31% ± 9%	Explore
memory B cell	6 studies	17% ± 2%	Explore
astrocyte	6 studies	30% ± 12%	Explore
connective tissue cell	6 studies	22% ± 4%	Explore
plasmacytoid dendritic cell	6 studies	23% ± 7%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	27% ± 5%	Explore
naive B cell	5 studies	19% ± 3%	Explore
glutamatergic neuron	5 studies	47% ± 17%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	23% ± 2%	Explore
innate lymphoid cell	5 studies	20% ± 4%	Explore
type II pneumocyte	5 studies	21% ± 4%	Explore
goblet cell	5 studies	32% ± 23%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	20% ± 6%	Explore
hematopoietic precursor cell	4 studies	27% ± 9%	Explore
squamous epithelial cell	4 studies	61% ± 16%	Explore
leukocyte	4 studies	23% ± 2%	Explore
brush cell	4 studies	27% ± 6%	Explore
mesothelial cell	4 studies	28% ± 5%	Explore
GABAergic neuron	4 studies	41% ± 8%	Explore
hematopoietic stem cell	4 studies	24% ± 8%	Explore
enteroendocrine cell	4 studies	19% ± 4%	Explore
transit amplifying cell	4 studies	34% ± 28%	Explore
oligodendrocyte	4 studies	22% ± 8%	Explore
exhausted T cell	3 studies	26% ± 7%	Explore
glomerular endothelial cell	3 studies	31% ± 2%	Explore
podocyte	3 studies	24% ± 4%	Explore
megakaryocyte	3 studies	31% ± 6%	Explore
mononuclear phagocyte	3 studies	25% ± 7%	Explore
abnormal cell	3 studies	24% ± 9%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	29% ± 4%	Explore
intermediate monocyte	3 studies	34% ± 13%	Explore
granulocyte	3 studies	28% ± 8%	Explore
adventitial cell	3 studies	18% ± 1%	Explore
T follicular helper cell	3 studies	18% ± 3%	Explore
group 3 innate lymphoid cell	3 studies	31% ± 12%	Explore
interneuron	3 studies	42% ± 12%	Explore
neuron	3 studies	31% ± 6%	Explore
T-helper 1 cell	3 studies	21% ± 3%	Explore
double negative thymocyte	3 studies	30% ± 5%	Explore
mucus secreting cell	3 studies	18% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	15 studies	29% ± 13%	Explore
peripheral blood	13 studies	25% ± 7%	Explore
brain	6 studies	34% ± 11%	Explore
intestine	4 studies	21% ± 4%	Explore
adipose	4 studies	23% ± 3%	Explore
bone marrow	3 studies	23% ± 7%	Explore
heart	3 studies	18% ± 2%	Explore
uterus	3 studies	30% ± 10%	Explore
kidney	3 studies	20% ± 1%	Explore
liver	3 studies	28% ± 10%	Explore
esophagus	3 studies	26% ± 10%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	5410.54	1445 / 1445	100%	37.01	183 / 183
lung	100%	5177.71	578 / 578	100%	28.02	1155 / 1155
ovary	100%	2058.71	180 / 180	100%	16.95	429 / 430
breast	100%	3245.87	459 / 459	100%	25.57	1113 / 1118
uterus	100%	2802.05	170 / 170	99%	31.26	456 / 459
stomach	100%	1943.15	359 / 359	99%	24.02	284 / 286
bladder	100%	2487.38	21 / 21	99%	24.41	500 / 504
prostate	100%	1999.64	245 / 245	99%	17.57	498 / 502
intestine	100%	2714.10	966 / 966	99%	24.04	522 / 527
thymus	100%	2839.55	652 / 653	99%	19.99	598 / 605
kidney	100%	2507.21	89 / 89	98%	21.23	887 / 901
skin	100%	4390.40	1808 / 1809	95%	17.35	449 / 472
brain	95%	1241.87	2523 / 2642	99%	11.02	695 / 705
liver	100%	1671.31	226 / 226	94%	12.63	380 / 406
pancreas	94%	1219.79	309 / 328	98%	28.09	174 / 178
adrenal gland	100%	2143.70	257 / 258	88%	9.18	202 / 230
adipose	100%	4162.62	1204 / 1204	0%	0	0 / 0
spleen	100%	2598.70	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	32.88	45 / 45
ureter	0%	0	0 / 0	100%	14.62	1 / 1
blood vessel	100%	2616.78	1333 / 1335	0%	0	0 / 0
peripheral blood	97%	2987.04	899 / 929	0%	0	0 / 0
heart	97%	1534.23	833 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	93%	14.43	27 / 29
eye	0%	0	0 / 0	64%	5.47	51 / 80
muscle	51%	428.22	407 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0007015	Biological process	actin filament organization
GO_1901992	Biological process	positive regulation of mitotic cell cycle phase transition
GO_0051694	Biological process	pointed-end actin filament capping
GO_0048821	Biological process	erythrocyte development
GO_0006936	Biological process	muscle contraction
GO_0098609	Biological process	cell-cell adhesion
GO_0030239	Biological process	myofibril assembly
GO_0044772	Biological process	mitotic cell cycle phase transition
GO_0030016	Cellular component	myofibril
GO_0005856	Cellular component	cytoskeleton
GO_0005912	Cellular component	adherens junction
GO_0005865	Cellular component	striated muscle thin filament
GO_0005523	Molecular function	tropomyosin binding
GO_0098641	Molecular function	cadherin binding involved in cell-cell adhesion
GO_0005515	Molecular function	protein binding
GO_0003779	Molecular function	actin binding

IV. Literature review

[source]

Gene name	TMOD3
Protein name	Tropomodulin 3 Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod)
Synonyms
Description	FUNCTION: Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton (By similarity). .
Accessions	ENST00000308580.12 H0YNJ8 ENST00000558455.1 Q9NYL9 ENST00000561438.5 H0YKU1 H0YNU8 ENST00000560549.5

TMOD3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review