CYTH1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	30 studies	33% ± 11%	Explore
B cell	29 studies	29% ± 11%	Explore
endothelial cell	29 studies	31% ± 11%	Explore
macrophage	27 studies	34% ± 20%	Explore
CD4-positive, alpha-beta T cell	26 studies	33% ± 11%	Explore
T cell	25 studies	28% ± 11%	Explore
regulatory T cell	22 studies	31% ± 9%	Explore
CD8-positive, alpha-beta T cell	19 studies	31% ± 11%	Explore
classical monocyte	19 studies	25% ± 9%	Explore
memory B cell	16 studies	26% ± 5%	Explore
naive B cell	16 studies	25% ± 6%	Explore
non-classical monocyte	16 studies	30% ± 13%	Explore
mature NK T cell	15 studies	29% ± 9%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	15 studies	35% ± 10%	Explore
oligodendrocyte	15 studies	39% ± 15%	Explore
dendritic cell	14 studies	40% ± 16%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	39% ± 8%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	28% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	14 studies	29% ± 6%	Explore
monocyte	13 studies	34% ± 13%	Explore
CD8-positive, alpha-beta memory T cell	13 studies	28% ± 9%	Explore
mucosal invariant T cell	13 studies	34% ± 10%	Explore
CD4-positive, alpha-beta memory T cell	12 studies	30% ± 9%	Explore
gamma-delta T cell	12 studies	31% ± 10%	Explore
microglial cell	11 studies	38% ± 13%	Explore
myeloid cell	11 studies	38% ± 18%	Explore
ciliated cell	10 studies	28% ± 11%	Explore
plasmacytoid dendritic cell	10 studies	26% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell	10 studies	34% ± 10%	Explore
endothelial cell of vascular tree	10 studies	27% ± 13%	Explore
astrocyte	10 studies	28% ± 12%	Explore
leukocyte	9 studies	35% ± 16%	Explore
oligodendrocyte precursor cell	9 studies	26% ± 11%	Explore
type I pneumocyte	8 studies	29% ± 9%	Explore
conventional dendritic cell	8 studies	27% ± 13%	Explore
vein endothelial cell	8 studies	34% ± 22%	Explore
retinal cone cell	7 studies	42% ± 13%	Explore
basal cell	7 studies	24% ± 10%	Explore
GABAergic neuron	7 studies	42% ± 15%	Explore
interneuron	6 studies	38% ± 17%	Explore
epithelial cell	6 studies	40% ± 18%	Explore
retinal rod cell	6 studies	33% ± 15%	Explore
endothelial cell of artery	6 studies	20% ± 4%	Explore
T follicular helper cell	6 studies	31% ± 8%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	37% ± 13%	Explore
plasmablast	5 studies	28% ± 8%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	28% ± 6%	Explore
neuron	5 studies	40% ± 16%	Explore
lymphocyte	5 studies	48% ± 24%	Explore
innate lymphoid cell	5 studies	31% ± 9%	Explore
club cell	5 studies	21% ± 5%	Explore
fibroblast	5 studies	19% ± 4%	Explore
type II pneumocyte	5 studies	26% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	32% ± 9%	Explore
secretory cell	4 studies	17% ± 2%	Explore
squamous epithelial cell	4 studies	40% ± 20%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	23% ± 6%	Explore
retinal bipolar neuron	4 studies	21% ± 3%	Explore
immature B cell	4 studies	27% ± 7%	Explore
amacrine cell	4 studies	23% ± 10%	Explore
capillary endothelial cell	4 studies	26% ± 7%	Explore
mononuclear phagocyte	4 studies	30% ± 11%	Explore
mast cell	4 studies	28% ± 12%	Explore
glutamatergic neuron	4 studies	46% ± 13%	Explore
goblet cell	4 studies	41% ± 30%	Explore
alveolar macrophage	4 studies	52% ± 22%	Explore
CD4-positive helper T cell	3 studies	32% ± 10%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	21% ± 4%	Explore
exhausted T cell	3 studies	31% ± 15%	Explore
GABAergic interneuron	3 studies	27% ± 6%	Explore
granule cell	3 studies	16% ± 1%	Explore
precursor B cell	3 studies	29% ± 3%	Explore
plasma cell	3 studies	38% ± 5%	Explore
retina horizontal cell	3 studies	20% ± 7%	Explore
tissue-resident macrophage	3 studies	35% ± 13%	Explore
glycinergic amacrine cell	3 studies	19% ± 2%	Explore
rod bipolar cell	3 studies	28% ± 9%	Explore
respiratory goblet cell	3 studies	23% ± 3%	Explore
hepatocyte	3 studies	32% ± 10%	Explore
T-helper 1 cell	3 studies	29% ± 9%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	35% ± 6%	Explore
abnormal cell	3 studies	31% ± 11%	Explore
mucus secreting cell	3 studies	25% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	16 studies	31% ± 9%	Explore
brain	14 studies	32% ± 16%	Explore
lung	9 studies	27% ± 10%	Explore
eye	6 studies	31% ± 11%	Explore
adipose	4 studies	23% ± 5%	Explore
bone marrow	3 studies	23% ± 8%	Explore
kidney	3 studies	18% ± 1%	Explore
liver	3 studies	27% ± 11%	Explore
lymph node	3 studies	24% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	5213.07	245 / 245	100%	38.45	502 / 502
esophagus	100%	4848.11	1444 / 1445	100%	31.20	183 / 183
lung	100%	9578.09	578 / 578	100%	35.35	1153 / 1155
intestine	100%	5108.47	966 / 966	100%	23.25	526 / 527
uterus	100%	2884.72	170 / 170	100%	30.42	458 / 459
breast	100%	4952.97	459 / 459	100%	28.70	1115 / 1118
thymus	100%	6142.36	652 / 653	100%	34.88	604 / 605
stomach	100%	4061.20	359 / 359	100%	21.56	285 / 286
bladder	100%	2908.29	21 / 21	100%	25.73	502 / 504
brain	100%	5145.76	2637 / 2642	100%	38.48	702 / 705
liver	100%	3046.83	225 / 226	100%	20.93	404 / 406
kidney	100%	3629.48	89 / 89	99%	19.85	889 / 901
pancreas	97%	2624.42	317 / 328	100%	37.56	178 / 178
adrenal gland	100%	4425.75	258 / 258	97%	25.73	222 / 230
ovary	100%	2230.97	180 / 180	97%	13.06	415 / 430
skin	97%	4562.46	1752 / 1809	99%	25.49	468 / 472
adipose	100%	5517.45	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	88.45	29 / 29
spleen	100%	11203.12	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	42.49	45 / 45
ureter	0%	0	0 / 0	100%	15.61	1 / 1
muscle	100%	3676.22	801 / 803	0%	0	0 / 0
peripheral blood	100%	12949.92	925 / 929	0%	0	0 / 0
heart	99%	2734.27	853 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	96%	17.32	77 / 80
blood vessel	96%	2372.78	1280 / 1335	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0016192	Biological process	vesicle-mediated transport
GO_0032012	Biological process	regulation of ARF protein signal transduction
GO_0030155	Biological process	regulation of cell adhesion
GO_0090162	Biological process	establishment of epithelial cell polarity
GO_0009898	Cellular component	cytoplasmic side of plasma membrane
GO_0000139	Cellular component	Golgi membrane
GO_0005829	Cellular component	cytosol
GO_0005912	Cellular component	adherens junction
GO_0005886	Cellular component	plasma membrane
GO_0005737	Cellular component	cytoplasm
GO_0005923	Cellular component	bicellular tight junction
GO_0005085	Molecular function	guanyl-nucleotide exchange factor activity
GO_0005515	Molecular function	protein binding
GO_0008289	Molecular function	lipid binding

IV. Literature review

[source]

Gene name	CYTH1
Protein name	Cytohesin-1 (PH, SEC7 and coiled-coil domain-containing protein 1) (SEC7 homolog B2-1) Cytohesin 1
Synonyms	D17S811E hCG_40471 PSCD1
Description	FUNCTION: Promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization, through regulation of ARF6 activity. .
Accessions	ENST00000591455.5 [Q15438-2] K7EKA2 ENST00000590300.1 Q15438 K7ERV8 ENST00000589768.6 ENST00000446868.8 [Q15438-1] K7ENH6 K7ENQ8 ENST00000591574.5 ENST00000586043.5 K7EJN5 ENST00000589297.5 [Q15438-3] ENST00000589296.5 ENST00000587308.5 ENST00000585509.5 [Q15438-3] K7EL72

CYTH1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review