OBSL1 | OmnibusX

Name	Number of supported studies	Average coverage
astrocyte	8 studies	27% ± 8%	Explore
endothelial cell	3 studies	21% ± 5%	Explore
fibroblast	3 studies	17% ± 3%	Explore
epithelial cell	3 studies	37% ± 4%	Explore
GABAergic neuron	3 studies	42% ± 10%	Explore
glutamatergic neuron	3 studies	40% ± 13%	Explore
oligodendrocyte precursor cell	3 studies	21% ± 3%	Explore

Name	Number of supported studies	Average coverage
brain	3 studies	30% ± 11%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	10101.56	245 / 245	99%	41.50	497 / 502
pancreas	100%	9012.10	328 / 328	98%	28.19	175 / 178
thymus	100%	23434.15	653 / 653	98%	59.29	594 / 605
adrenal gland	100%	15350.80	258 / 258	98%	54.81	225 / 230
ovary	100%	50551.30	180 / 180	98%	53.41	420 / 430
brain	94%	5654.07	2487 / 2642	100%	55.55	703 / 705
breast	100%	8192.00	457 / 459	94%	29.40	1054 / 1118
skin	98%	3971.50	1770 / 1809	95%	36.01	447 / 472
kidney	100%	10397.54	89 / 89	89%	34.48	802 / 901
lung	97%	5785.38	560 / 578	79%	21.81	910 / 1155
uterus	100%	12581.76	170 / 170	73%	29.87	337 / 459
bladder	100%	6333.95	21 / 21	72%	18.25	361 / 504
liver	96%	2988.58	217 / 226	67%	20.52	273 / 406
esophagus	91%	5521.97	1317 / 1445	62%	14.71	113 / 183
stomach	98%	5362.81	353 / 359	37%	7.74	106 / 286
intestine	90%	4955.91	866 / 966	32%	6.84	168 / 527
eye	0%	0	0 / 0	100%	54.72	80 / 80
blood vessel	100%	7792.76	1333 / 1335	0%	0	0 / 0
adipose	100%	6860.19	1200 / 1204	0%	0	0 / 0
muscle	99%	7373.56	797 / 803	0%	0	0 / 0
spleen	98%	4283.16	237 / 241	0%	0	0 / 0
heart	96%	12188.40	830 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	56%	8.81	25 / 45
lymph node	0%	0	0 / 0	3%	0.28	1 / 29
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007088	Biological process	regulation of mitotic nuclear division
GO_0007030	Biological process	Golgi organization
GO_0007010	Biological process	cytoskeleton organization
GO_0050775	Biological process	positive regulation of dendrite morphogenesis
GO_0000226	Biological process	microtubule cytoskeleton organization
GO_0055003	Biological process	cardiac myofibril assembly
GO_0034067	Biological process	protein localization to Golgi apparatus
GO_0005813	Cellular component	centrosome
GO_0031430	Cellular component	M band
GO_0005829	Cellular component	cytosol
GO_0030018	Cellular component	Z disc
GO_0005794	Cellular component	Golgi apparatus
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0014704	Cellular component	intercalated disc
GO_0005737	Cellular component	cytoplasm
GO_1990393	Cellular component	3M complex
GO_0008093	Molecular function	cytoskeletal anchor activity
GO_0005515	Molecular function	protein binding

Gene name	OBSL1
Protein name	Obscurin-like protein 1 Obscurin like cytoskeletal adaptor 1 OBSL1 protein
Synonyms	KIAA0657
Description	FUNCTION: Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer . Acts as a regulator of the Cul7-RING(FBXW8) ubiquitin-protein ligase, playing a critical role in the ubiquitin ligase pathway that regulates Golgi morphogenesis and dendrite patterning in brain. Required to localize CUL7 to the Golgi apparatus in neurons. .
Accessions	ENST00000456147.1 ENST00000604031.5 ENST00000603926.5 [O75147-4] A8MSZ8 H0Y684 ENST00000373873.8 [O75147-2] S4R463 ENST00000373876.5 Q6P710 A6NN50 ENST00000289656.3 O75147 ENST00000404537.6 [O75147-3]

OBSL1 report