ATP1B1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0010468Biological processregulation of gene expression
GO_0010882Biological processregulation of cardiac muscle contraction by calcium ion signaling
GO_1903408Biological processpositive regulation of P-type sodium:potassium-exchanging transporter activity
GO_0072659Biological processprotein localization to plasma membrane
GO_0032781Biological processpositive regulation of ATP-dependent activity
GO_0036376Biological processsodium ion export across plasma membrane
GO_0045087Biological processinnate immune response
GO_0086064Biological processcell communication by electrical coupling involved in cardiac conduction
GO_1901018Biological processpositive regulation of potassium ion transmembrane transporter activity
GO_0007155Biological processcell adhesion
GO_0006874Biological processintracellular calcium ion homeostasis
GO_0046034Biological processATP metabolic process
GO_0006883Biological processintracellular sodium ion homeostasis
GO_0055119Biological processrelaxation of cardiac muscle
GO_0060048Biological processcardiac muscle contraction
GO_0086013Biological processmembrane repolarization during cardiac muscle cell action potential
GO_1903278Biological processpositive regulation of sodium ion export across plasma membrane
GO_0098655Biological processmonoatomic cation transmembrane transport
GO_0010248Biological processestablishment or maintenance of transmembrane electrochemical gradient
GO_0050821Biological processprotein stabilization
GO_1903288Biological processpositive regulation of potassium ion import across plasma membrane
GO_1903281Biological processpositive regulation of calcium:sodium antiporter activity
GO_0086009Biological processmembrane repolarization
GO_0030007Biological processintracellular potassium ion homeostasis
GO_0044861Biological processprotein transport into plasma membrane raft
GO_0035725Biological processsodium ion transmembrane transport
GO_1902600Biological processproton transmembrane transport
GO_1990573Biological processpotassium ion import across plasma membrane
GO_0016324Cellular componentapical plasma membrane
GO_0036126Cellular componentsperm flagellum
GO_0005890Cellular componentsodium:potassium-exchanging ATPase complex
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0042383Cellular componentsarcolemma
GO_1903561Cellular componentextracellular vesicle
GO_0070062Cellular componentextracellular exosome
GO_0030315Cellular componentT-tubule
GO_0016328Cellular componentlateral plasma membrane
GO_0031090Cellular componentorganelle membrane
GO_0014704Cellular componentintercalated disc
GO_0016323Cellular componentbasolateral plasma membrane
GO_0001671Molecular functionATPase activator activity
GO_0019901Molecular functionprotein kinase binding
GO_0005391Molecular functionP-type sodium:potassium-exchanging transporter activity
GO_0030674Molecular functionprotein-macromolecule adaptor activity
GO_0051117Molecular functionATPase binding
GO_0046982Molecular functionprotein heterodimerization activity
GO_0023026Molecular functionMHC class II protein complex binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameATP1B1
Protein nameAlternative protein ATP1B1
Sodium/potassium-transporting ATPase subunit beta
Sodium/potassium-transporting ATPase subunit beta-1 (Sodium/potassium-dependent ATPase subunit beta-1)
SynonymsATP1B
hCG_37798
DescriptionFUNCTION: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane . Plays a role in innate immunity by enhancing virus-triggered induction of interferons (IFNs) and interferon stimulated genes (ISGs). Mechanistically, enhances the ubiquitination of TRAF3 and TRAF6 as well as the phosphorylation of TAK1 and TBK1 . .; FUNCTION: Involved in cell adhesion and establishing epithelial cell polarity. .

FUNCTION: Involved in cell adhesion and establishing epithelial cell polarity. .; FUNCTION: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. .

FUNCTION: Involved in cell adhesion and establishing epithelial cell polarity. .; FUNCTION: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. .

FUNCTION: Involved in cell adhesion and establishing epithelial cell polarity. .; FUNCTION: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. .

FUNCTION: Involved in cell adhesion and establishing epithelial cell polarity. .; FUNCTION: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. .

FUNCTION: Involved in cell adhesion and establishing epithelial cell polarity. .

FUNCTION: Involved in cell adhesion and establishing epithelial cell polarity. .; FUNCTION: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. .

AccessionsA3KLL5
ENST00000690184.1 [P05026-1]
ENST00000691106.1
Q58I20
ENST00000688755.1
ENST00000685155.1
ENST00000687745.1
ENST00000685762.1
P05026
ENST00000686702.1
ENST00000689522.1 [P05026-1]
B7Z9S8
ENST00000691753.1
A0A8I5KX89
A0A8I5KNT2
Q6LEU2
ENST00000367816.5 [P05026-1]
ENST00000494797.2
L0R585
ENST00000685792.1
ENST00000367815.9 [P05026-1]
ENST00000691802.1