Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| fibroblast | 33 studies | 40% ± 16% | |
| pericyte | 22 studies | 43% ± 16% | |
| smooth muscle cell | 21 studies | 43% ± 15% | |
| connective tissue cell | 13 studies | 40% ± 10% | |
| myofibroblast cell | 11 studies | 37% ± 12% | |
| astrocyte | 10 studies | 33% ± 11% | |
| glial cell | 6 studies | 63% ± 27% | |
| mesothelial cell | 4 studies | 30% ± 20% | |
| ciliated cell | 4 studies | 37% ± 13% | |
| adventitial cell | 4 studies | 32% ± 12% | |
| podocyte | 3 studies | 33% ± 10% | |
| Schwann cell | 3 studies | 65% ± 34% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| intestine | 3 studies | 26% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 95% | 4889.19 | 215 / 226 | 29% | 0.71 | 117 / 406 |
| brain | 99% | 4488.66 | 2608 / 2642 | 9% | 0.15 | 63 / 705 |
| ovary | 99% | 3016.88 | 179 / 180 | 5% | 0.11 | 21 / 430 |
| uterus | 99% | 4845.57 | 169 / 170 | 2% | 0.03 | 7 / 459 |
| blood vessel | 100% | 6454.04 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 100% | 11476.67 | 803 / 803 | 0% | 0 | 0 / 0 |
| heart | 99% | 7089.98 | 850 / 861 | 0% | 0 | 0 / 0 |
| breast | 98% | 2754.97 | 451 / 459 | 0% | 0.01 | 4 / 1118 |
| adipose | 96% | 2747.37 | 1155 / 1204 | 0% | 0 | 0 / 0 |
| prostate | 86% | 2455.12 | 211 / 245 | 1% | 0.01 | 3 / 502 |
| lung | 83% | 1679.41 | 477 / 578 | 0% | 0.00 | 2 / 1155 |
| intestine | 75% | 2402.76 | 725 / 966 | 0% | 0.00 | 1 / 527 |
| bladder | 71% | 1582.95 | 15 / 21 | 1% | 0.01 | 3 / 504 |
| esophagus | 69% | 2288.65 | 990 / 1445 | 0% | 0 | 0 / 183 |
| skin | 34% | 486.07 | 624 / 1809 | 10% | 0.20 | 45 / 472 |
| stomach | 41% | 1109.36 | 146 / 359 | 1% | 0.01 | 2 / 286 |
| thymus | 39% | 539.71 | 256 / 653 | 0% | 0 | 0 / 605 |
| kidney | 19% | 272.64 | 17 / 89 | 8% | 0.18 | 71 / 901 |
| spleen | 7% | 89.08 | 18 / 241 | 0% | 0 | 0 / 0 |
| adrenal gland | 4% | 50.14 | 11 / 258 | 0% | 0.01 | 1 / 230 |
| eye | 0% | 0 | 0 / 0 | 4% | 0.05 | 3 / 80 |
| peripheral blood | 1% | 21.23 | 11 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| pancreas | 0% | 0 | 0 / 328 | 0% | 0 | 0 / 178 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_2000649 | Biological process | regulation of sodium ion transmembrane transporter activity |
| GO_0006813 | Biological process | potassium ion transport |
| GO_0006821 | Biological process | chloride transport |
| GO_0006936 | Biological process | muscle contraction |
| GO_1903278 | Biological process | positive regulation of sodium ion export across plasma membrane |
| GO_1902476 | Biological process | chloride transmembrane transport |
| GO_0006814 | Biological process | sodium ion transport |
| GO_0010734 | Biological process | negative regulation of protein glutathionylation |
| GO_0086036 | Biological process | regulation of cardiac muscle cell membrane potential |
| GO_0008016 | Biological process | regulation of heart contraction |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0005890 | Cellular component | sodium:potassium-exchanging ATPase complex |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0014704 | Cellular component | intercalated disc |
| GO_0042383 | Cellular component | sarcolemma |
| GO_0030315 | Cellular component | T-tubule |
| GO_0005901 | Cellular component | caveola |
| GO_0044325 | Molecular function | transmembrane transporter binding |
| GO_0017080 | Molecular function | sodium channel regulator activity |
| GO_0005254 | Molecular function | chloride channel activity |
| Gene name | FXYD1 |
| Protein name | Phospholemman (FXYD domain-containing ion transport regulator 1) (Sodium/potassium-transporting ATPase subunit FXYD1) FXYD domain-containing ion transport regulator |
| Synonyms | PLM |
| Description | FUNCTION: Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Inhibits NKA activity in its unphosphorylated state and stimulates activity when phosphorylated. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1. Contributes to female sexual development by maintaining the excitability of neurons which secrete gonadotropin-releasing hormone. . |
| Accessions | ENST00000351325.9 K7EQG4 ENST00000612146.4 ENST00000588715.5 ENST00000589121.1 ENST00000588081.5 ENST00000455515.6 C7E9P5 ENST00000589209.5 ENST00000588607.5 O00168 |