Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 19 studies | 41% ± 24% | |
oligodendrocyte | 17 studies | 80% ± 19% | |
oligodendrocyte precursor cell | 15 studies | 64% ± 18% | |
glutamatergic neuron | 13 studies | 85% ± 14% | |
epithelial cell | 11 studies | 38% ± 20% | |
GABAergic neuron | 11 studies | 80% ± 20% | |
type II pneumocyte | 10 studies | 59% ± 32% | |
basal cell | 10 studies | 44% ± 26% | |
endothelial cell | 10 studies | 45% ± 21% | |
microglial cell | 10 studies | 44% ± 22% | |
astrocyte | 9 studies | 39% ± 22% | |
fibroblast | 9 studies | 42% ± 22% | |
club cell | 8 studies | 48% ± 27% | |
neuron | 8 studies | 59% ± 23% | |
amacrine cell | 8 studies | 67% ± 22% | |
retinal rod cell | 8 studies | 58% ± 33% | |
type I pneumocyte | 7 studies | 43% ± 18% | |
interneuron | 7 studies | 78% ± 21% | |
retinal ganglion cell | 7 studies | 93% ± 10% | |
retinal cone cell | 7 studies | 61% ± 29% | |
respiratory goblet cell | 6 studies | 46% ± 25% | |
glial cell | 6 studies | 52% ± 24% | |
retina horizontal cell | 6 studies | 37% ± 23% | |
cardiac muscle cell | 6 studies | 63% ± 23% | |
T cell | 6 studies | 42% ± 18% | |
epithelial cell of proximal tubule | 5 studies | 47% ± 33% | |
retinal bipolar neuron | 5 studies | 81% ± 15% | |
OFF-bipolar cell | 5 studies | 71% ± 29% | |
ON-bipolar cell | 5 studies | 79% ± 29% | |
kidney loop of Henle epithelial cell | 5 studies | 50% ± 29% | |
B cell | 5 studies | 22% ± 3% | |
CD4-positive, alpha-beta T cell | 5 studies | 41% ± 17% | |
Mueller cell | 5 studies | 34% ± 20% | |
kidney distal convoluted tubule epithelial cell | 4 studies | 55% ± 33% | |
granule cell | 4 studies | 89% ± 6% | |
macrophage | 4 studies | 38% ± 17% | |
CD8-positive, alpha-beta T cell | 4 studies | 26% ± 4% | |
lymphocyte | 4 studies | 39% ± 15% | |
Schwann cell | 4 studies | 68% ± 15% | |
ionocyte | 3 studies | 29% ± 6% | |
secretory cell | 3 studies | 31% ± 6% | |
cholangiocyte | 3 studies | 49% ± 20% | |
hepatic stellate cell | 3 studies | 55% ± 13% | |
GABAergic interneuron | 3 studies | 92% ± 4% | |
pericyte | 3 studies | 36% ± 18% | |
effector memory CD8-positive, alpha-beta T cell | 3 studies | 28% ± 9% | |
mesothelial cell | 3 studies | 35% ± 15% | |
naive thymus-derived CD4-positive, alpha-beta T cell | 3 studies | 43% ± 19% | |
GABAergic amacrine cell | 3 studies | 90% ± 7% | |
glycinergic amacrine cell | 3 studies | 89% ± 8% | |
rod bipolar cell | 3 studies | 92% ± 8% | |
retinal pigment epithelial cell | 3 studies | 42% ± 15% | |
renal alpha-intercalated cell | 3 studies | 40% ± 19% | |
renal principal cell | 3 studies | 75% ± 26% | |
mucus secreting cell | 3 studies | 56% ± 21% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 98% | 2370.67 | 240 / 245 | 98% | 11.90 | 494 / 502 |
thymus | 100% | 2872.92 | 650 / 653 | 93% | 6.82 | 560 / 605 |
kidney | 100% | 3458.15 | 89 / 89 | 88% | 8.76 | 791 / 901 |
esophagus | 96% | 2102.90 | 1394 / 1445 | 91% | 5.42 | 166 / 183 |
brain | 100% | 10910.90 | 2634 / 2642 | 70% | 6.06 | 493 / 705 |
intestine | 99% | 3549.29 | 960 / 966 | 62% | 2.14 | 326 / 527 |
stomach | 88% | 1345.10 | 315 / 359 | 72% | 2.78 | 205 / 286 |
uterus | 86% | 1653.00 | 146 / 170 | 70% | 3.73 | 321 / 459 |
ovary | 87% | 1334.81 | 156 / 180 | 64% | 2.67 | 275 / 430 |
lung | 64% | 1295.34 | 370 / 578 | 82% | 4.82 | 946 / 1155 |
breast | 50% | 809.33 | 229 / 459 | 89% | 7.29 | 997 / 1118 |
bladder | 76% | 1258.67 | 16 / 21 | 58% | 2.59 | 293 / 504 |
pancreas | 47% | 538.67 | 155 / 328 | 64% | 2.74 | 114 / 178 |
ureter | 0% | 0 | 0 / 0 | 100% | 2.55 | 1 / 1 |
muscle | 99% | 4252.40 | 798 / 803 | 0% | 0 | 0 / 0 |
heart | 93% | 5599.98 | 801 / 861 | 0% | 0 | 0 / 0 |
spleen | 91% | 1941.14 | 220 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 78% | 4.30 | 35 / 45 |
skin | 72% | 2845.21 | 1302 / 1809 | 6% | 0.41 | 27 / 472 |
adrenal gland | 28% | 351.63 | 71 / 258 | 40% | 2.07 | 92 / 230 |
blood vessel | 60% | 1377.47 | 804 / 1335 | 0% | 0 | 0 / 0 |
liver | 31% | 420.55 | 71 / 226 | 15% | 0.80 | 61 / 406 |
adipose | 22% | 253.84 | 264 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.13 | 1 / 29 |
eye | 0% | 0 | 0 / 0 | 3% | 0.15 | 2 / 80 |
peripheral blood | 0% | 2.79 | 1 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0010650 | Biological process | positive regulation of cell communication by electrical coupling |
GO_2001259 | Biological process | positive regulation of cation channel activity |
GO_1900827 | Biological process | positive regulation of membrane depolarization during cardiac muscle cell action potential |
GO_0072660 | Biological process | maintenance of protein location in plasma membrane |
GO_0072659 | Biological process | protein localization to plasma membrane |
GO_0045184 | Biological process | establishment of protein localization |
GO_0007165 | Biological process | signal transduction |
GO_0010628 | Biological process | positive regulation of gene expression |
GO_0000281 | Biological process | mitotic cytokinesis |
GO_0007010 | Biological process | cytoskeleton organization |
GO_0043266 | Biological process | regulation of potassium ion transport |
GO_0099612 | Biological process | protein localization to axon |
GO_0007528 | Biological process | neuromuscular junction development |
GO_0071286 | Biological process | cellular response to magnesium ion |
GO_0007409 | Biological process | axonogenesis |
GO_1902260 | Biological process | negative regulation of delayed rectifier potassium channel activity |
GO_0010765 | Biological process | positive regulation of sodium ion transport |
GO_0045838 | Biological process | positive regulation of membrane potential |
GO_0019228 | Biological process | neuronal action potential |
GO_0007009 | Biological process | plasma membrane organization |
GO_0090314 | Biological process | positive regulation of protein targeting to membrane |
GO_2000651 | Biological process | positive regulation of sodium ion transmembrane transporter activity |
GO_0010960 | Biological process | magnesium ion homeostasis |
GO_0034112 | Biological process | positive regulation of homotypic cell-cell adhesion |
GO_0071709 | Biological process | membrane assembly |
GO_0043001 | Biological process | Golgi to plasma membrane protein transport |
GO_0005886 | Cellular component | plasma membrane |
GO_0031594 | Cellular component | neuromuscular junction |
GO_0043034 | Cellular component | costamere |
GO_0030018 | Cellular component | Z disc |
GO_0005764 | Cellular component | lysosome |
GO_0042383 | Cellular component | sarcolemma |
GO_0043194 | Cellular component | axon initial segment |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0009925 | Cellular component | basal plasma membrane |
GO_0043005 | Cellular component | neuron projection |
GO_0030425 | Cellular component | dendrite |
GO_0014731 | Cellular component | spectrin-associated cytoskeleton |
GO_0009986 | Cellular component | cell surface |
GO_0030315 | Cellular component | T-tubule |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0005829 | Cellular component | cytosol |
GO_0016529 | Cellular component | sarcoplasmic reticulum |
GO_0016328 | Cellular component | lateral plasma membrane |
GO_0045211 | Cellular component | postsynaptic membrane |
GO_0005923 | Cellular component | bicellular tight junction |
GO_0033268 | Cellular component | node of Ranvier |
GO_0014704 | Cellular component | intercalated disc |
GO_0016323 | Cellular component | basolateral plasma membrane |
GO_0030507 | Molecular function | spectrin binding |
GO_0045296 | Molecular function | cadherin binding |
GO_0005200 | Molecular function | structural constituent of cytoskeleton |
GO_0030674 | Molecular function | protein-macromolecule adaptor activity |
GO_0044325 | Molecular function | transmembrane transporter binding |
GO_0008093 | Molecular function | cytoskeletal anchor activity |
GO_0008092 | Molecular function | cytoskeletal protein binding |
GO_0005515 | Molecular function | protein binding |
Gene name | ANK3 |
Protein name | Ankyrin 3, node of Ranvier (Ankyrin G), isoform CRA_d (cDNA FLJ78657, highly similar to Homo sapiens ankyrin 3, node of Ranvier (ankyrin G) (ANK3), transcript variant 2, mRNA) Ankyrin-3 (ANK-3) (Ankyrin-G) Ankyrin 3 |
Synonyms | hCG_1812776 |
Description | FUNCTION: Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments . In skeletal muscle, required for costamere localization of DMD and betaDAG1 (By similarity). Regulates KCNA1 channel activity in function of dietary Mg(2+) levels, and thereby contributes to the regulation of renal Mg(2+) reabsorption . Required for intracellular adhesion and junctional conductance in myocytes, potentially via stabilization of GJA1/CX43 protein abundance and promotion of PKP2, GJA1/CX43, and SCN5A/Nav1.5 localization to cell-cell junctions (By similarity). .; FUNCTION: [Isoform 5]: May be part of a Golgi-specific membrane cytoskeleton in association with beta-spectrin. . |
Accessions | A0A087X0L3 D6RHY3 ENST00000474360.1 A0A087WY90 D6RFK6 H0Y951 ENST00000280772.7 [Q12955-3] ENST00000618080.4 H0YA66 ENST00000616444.4 Q12955 A8KA62 ENST00000617800.4 ENST00000506635.5 ENST00000373820.5 A0A087WX55 B1AQT1 A0A087WTP5 ENST00000503366.6 [Q12955-4] ENST00000613207.4 A0A087WZ65 ENST00000460468.5 ENST00000373827.6 [Q12955-5] ENST00000610321.4 H0Y8Z4 ENST00000514197.5 A0A087WVC2 ENST00000610901.4 A0A087WTE8 H0YAH5 ENST00000622427.4 ENST00000612776.4 D6RBY7 ENST00000503925.1 ENST00000373815.5 ENST00000486349.2 ENST00000511043.5 A0A087X0B4 H0Y3A4 A0A087WTF3 ENST00000513049.5 ENST00000459732.2 ENST00000467420.7 A0A087WWI5 ENST00000355288.6 [Q12955-6] A0A087WZ26 D6RF31 H0Y9E9 ENST00000502769.5 ENST00000621739.1 |