AKAP6 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1901381Biological processpositive regulation of potassium ion transmembrane transport
GO_1902261Biological processpositive regulation of delayed rectifier potassium channel activity
GO_0030307Biological processpositive regulation of cell growth
GO_0061051Biological processpositive regulation of cell growth involved in cardiac muscle cell development
GO_0070886Biological processpositive regulation of calcineurin-NFAT signaling cascade
GO_0006605Biological processprotein targeting
GO_0060316Biological processpositive regulation of ryanodine-sensitive calcium-release channel activity
GO_0060306Biological processregulation of membrane repolarization
GO_0010738Biological processregulation of protein kinase A signaling
GO_0071345Biological processcellular response to cytokine stimulus
GO_0071320Biological processcellular response to cAMP
GO_0007189Biological processadenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0051281Biological processpositive regulation of release of sequestered calcium ion into cytosol
GO_0010880Biological processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO_0001508Biological processaction potential
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0005635Cellular componentnuclear envelope
GO_0014701Cellular componentjunctional sarcoplasmic reticulum membrane
GO_0030315Cellular componentT-tubule
GO_0034704Cellular componentcalcium channel complex
GO_0016529Cellular componentsarcoplasmic reticulum
GO_0005737Cellular componentcytoplasm
GO_0031965Cellular componentnuclear membrane
GO_0005901Cellular componentcaveola
GO_0014704Cellular componentintercalated disc
GO_0034237Molecular functionprotein kinase A regulatory subunit binding
GO_0043495Molecular functionprotein-membrane adaptor activity
GO_0060090Molecular functionmolecular adaptor activity
GO_0044325Molecular functiontransmembrane transporter binding
GO_0008179Molecular functionadenylate cyclase binding
GO_0051018Molecular functionprotein kinase A binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameAKAP6
Protein nameA-kinase anchor protein 6 (AKAP-6) (A-kinase anchor protein 100 kDa) (AKAP 100) (Protein kinase A-anchoring protein 6) (PRKA6) (mAKAP)
A kinase (PRKA) anchor protein 6
A-kinase anchoring protein 6
SynonymsAKAP100
KIAA0311
DescriptionFUNCTION: Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the nuclear membrane or sarcoplasmic reticulum. May act as an adapter for assembling multiprotein complexes.

AccessionsENST00000553547.5
ENST00000280979.9 [Q13023-1]
ENST00000557354.5 [Q13023-2]
G3V3H6
ENST00000556638.1
Q13023
ENST00000554410.5
G3V569
B2RP22
H0YJT7
G3V3H7
ENST00000557102.1
ENST00000554740.1
G3V3H2
G3V3B5
ENST00000557272.1