SCN4B | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of SCN4B at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	93%	8339.71	2458 / 2642	99%	35.91	700 / 705
thymus	99%	4512.58	649 / 653	90%	26.57	544 / 605
breast	90%	2865.65	415 / 459	71%	5.45	794 / 1118
prostate	83%	1156.36	204 / 245	72%	3.10	363 / 502
lung	84%	1981.72	484 / 578	55%	3.36	636 / 1155
adrenal gland	48%	758.96	123 / 258	69%	6.41	158 / 230
esophagus	64%	1120.27	931 / 1445	41%	2.35	75 / 183
kidney	26%	300.71	23 / 89	72%	15.01	649 / 901
pancreas	11%	104.30	37 / 328	82%	5.55	146 / 178
adipose	87%	2798.79	1053 / 1204	0%	0	0 / 0
heart	87%	1927.59	753 / 861	0%	0	0 / 0
skin	32%	384.46	582 / 1809	53%	5.35	249 / 472
muscle	84%	1506.08	673 / 803	0%	0	0 / 0
uterus	47%	616.60	80 / 170	25%	1.91	117 / 459
intestine	43%	539.05	419 / 966	17%	0.84	92 / 527
bladder	33%	580.67	7 / 21	23%	1.18	115 / 504
stomach	25%	260.75	91 / 359	23%	1.28	65 / 286
ovary	5%	89.14	9 / 180	24%	1.12	105 / 430
blood vessel	26%	343.33	350 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	25%	1.50	20 / 80
tonsil	0%	0	0 / 0	24%	0.95	11 / 45
liver	1%	7.21	2 / 226	18%	0.61	74 / 406
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0086012	Biological process	membrane depolarization during cardiac muscle cell action potential
GO_2000649	Biological process	regulation of sodium ion transmembrane transporter activity
GO_0060307	Biological process	regulation of ventricular cardiac muscle cell membrane repolarization
GO_0086002	Biological process	cardiac muscle cell action potential involved in contraction
GO_0086016	Biological process	AV node cell action potential
GO_0060048	Biological process	cardiac muscle contraction
GO_0051649	Biological process	establishment of localization in cell
GO_0010765	Biological process	positive regulation of sodium ion transport
GO_0006814	Biological process	sodium ion transport
GO_0019228	Biological process	neuronal action potential
GO_0086091	Biological process	regulation of heart rate by cardiac conduction
GO_0035725	Biological process	sodium ion transmembrane transport
GO_0005886	Cellular component	plasma membrane
GO_0001518	Cellular component	voltage-gated sodium channel complex
GO_0014704	Cellular component	intercalated disc
GO_0086006	Molecular function	voltage-gated sodium channel activity involved in cardiac muscle cell action potential
GO_0005248	Molecular function	voltage-gated sodium channel activity
GO_0044325	Molecular function	transmembrane transporter binding
GO_0017080	Molecular function	sodium channel regulator activity
GO_0005515	Molecular function	protein binding

Gene name	SCN4B
Protein name	Sodium channel subunit beta-4 Sodium channel beta-4 subunit (Sodium channel, voltage-gated, type IV, beta, isoform CRA_b) (cDNA, FLJ95353, Homo sapiens sodium channel, voltage-gated, type IV, beta (SCN4B),mRNA)
Synonyms	hCG_1646677
Description	FUNCTION: Modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation. Modulates the susceptibility of the sodium channel to inhibition by toxic peptides from spider, scorpion, wasp and sea anemone venom. .
Accessions	ENST00000324727.9 [Q8IWT1-1] B0YJ93 Q8IWT1 ENST00000529878.1 [Q8IWT1-3]

SCN4B report