FGF13 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
GABAergic neuron	9 studies	49% ± 19%	Explore
glutamatergic neuron	9 studies	45% ± 20%	Explore
macrophage	8 studies	29% ± 12%	Explore
adipocyte	8 studies	28% ± 6%	Explore
neuron	7 studies	54% ± 20%	Explore
interneuron	6 studies	62% ± 7%	Explore
myeloid cell	5 studies	22% ± 6%	Explore
endothelial cell	4 studies	32% ± 21%	Explore
epithelial cell	4 studies	24% ± 6%	Explore
cholangiocyte	3 studies	45% ± 21%	Explore
GABAergic interneuron	3 studies	47% ± 6%	Explore
amacrine cell	3 studies	48% ± 23%	Explore
GABAergic amacrine cell	3 studies	53% ± 14%	Explore
glycinergic amacrine cell	3 studies	48% ± 19%	Explore
myofibroblast cell	3 studies	18% ± 0%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	11 studies	34% ± 17%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	1036.92	244 / 245	99%	6.91	499 / 502
breast	98%	632.51	449 / 459	72%	2.40	803 / 1118
brain	77%	3719.04	2040 / 2642	75%	3.46	528 / 705
kidney	94%	462.29	84 / 89	57%	1.26	512 / 901
uterus	95%	802.92	161 / 170	19%	0.80	89 / 459
thymus	83%	387.35	545 / 653	29%	0.98	178 / 605
ovary	82%	352.07	147 / 180	21%	0.39	89 / 430
blood vessel	100%	1628.27	1333 / 1335	0%	0	0 / 0
muscle	100%	1025.03	801 / 803	0%	0	0 / 0
bladder	90%	515.24	19 / 21	8%	0.21	41 / 504
adipose	98%	694.19	1174 / 1204	0%	0	0 / 0
stomach	79%	302.31	284 / 359	13%	0.33	37 / 286
spleen	90%	498.70	218 / 241	0%	0	0 / 0
lung	51%	179.53	297 / 578	36%	0.96	411 / 1155
esophagus	64%	410.60	925 / 1445	20%	0.49	37 / 183
intestine	74%	508.45	718 / 966	10%	0.21	52 / 527
skin	14%	47.57	249 / 1809	53%	1.85	250 / 472
eye	0%	0	0 / 0	35%	0.59	28 / 80
liver	1%	2.14	2 / 226	30%	0.81	122 / 406
peripheral blood	26%	173.57	242 / 929	0%	0	0 / 0
adrenal gland	2%	6.62	6 / 258	13%	0.60	31 / 230
pancreas	1%	3.95	4 / 328	13%	0.35	23 / 178
tonsil	0%	0	0 / 0	9%	0.23	4 / 45
heart	8%	25.64	69 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	7%	0.14	2 / 29
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0045200	Biological process	establishment of neuroblast polarity
GO_0021766	Biological process	hippocampus development
GO_0072659	Biological process	protein localization to plasma membrane
GO_0098909	Biological process	regulation of cardiac muscle cell action potential involved in regulation of contraction
GO_0000165	Biological process	MAPK cascade
GO_0007612	Biological process	learning
GO_0007165	Biological process	signal transduction
GO_0001764	Biological process	neuron migration
GO_0007026	Biological process	negative regulation of microtubule depolymerization
GO_0021795	Biological process	cerebral cortex cell migration
GO_0007267	Biological process	cell-cell signaling
GO_1905152	Biological process	positive regulation of voltage-gated sodium channel activity
GO_1904862	Biological process	inhibitory synapse assembly
GO_0046785	Biological process	microtubule polymerization
GO_0006814	Biological process	sodium ion transport
GO_0007613	Biological process	memory
GO_0048755	Biological process	branching morphogenesis of a nerve
GO_1905150	Biological process	regulation of voltage-gated sodium channel activity
GO_0048671	Biological process	negative regulation of collateral sprouting
GO_0007399	Biological process	nervous system development
GO_0005886	Cellular component	plasma membrane
GO_0005874	Cellular component	microtubule
GO_0042383	Cellular component	sarcolemma
GO_0043005	Cellular component	neuron projection
GO_0030425	Cellular component	dendrite
GO_0030175	Cellular component	filopodium
GO_0005829	Cellular component	cytosol
GO_0030426	Cellular component	growth cone
GO_0016328	Cellular component	lateral plasma membrane
GO_0005737	Cellular component	cytoplasm
GO_0030424	Cellular component	axon
GO_0014704	Cellular component	intercalated disc
GO_0005634	Cellular component	nucleus
GO_0048487	Molecular function	beta-tubulin binding
GO_0008083	Molecular function	growth factor activity
GO_0008017	Molecular function	microtubule binding
GO_0044325	Molecular function	transmembrane transporter binding
GO_0017080	Molecular function	sodium channel regulator activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	FGF13
Protein name	Fibroblast growth factor 13 isoform 1y1v Fibroblast growth factor 13 (FGF-13) (Fibroblast growth factor homologous factor 2) (FHF-2) Fibroblast growth factor (FGF) Fibroblast growth factor 13
Synonyms	FGF1C hCG_14696 FHF2
Description	FUNCTION: Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules (By similarity). Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching (By similarity). Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus (By similarity). Regulates voltage-gated sodium channel transport and function . May also play a role in MAPK signaling (By similarity). Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons (By similarity). .
Accessions	ENST00000626909.2 [Q92913-4] B1AJW0 ENST00000421460.1 B1B1H9 ENST00000455663.5 ENST00000315930.11 [Q92913-1] Q9Y643 ENST00000448673.1 A0A0C4DG13 ENST00000436198.6 [Q92913-3] ENST00000305414.9 [Q92913-2] Q92913 ENST00000441825.8 [Q92913-5] A8K1P5

FGF13 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review