integrin-mediated signaling pathway

I. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1CD40LG-ITGA2B+ITGB3CD40L_HUMAN - Ligand-Receptor
2CD40LG-ITGA5+ITGB1CD40L_HUMAN - Ligand-Receptor
3COL16A1-ITGA10+ITGB1COGA1_HUMAN - Adhesion-AdhesionAdhesion by Collagen/Integrin
4COL16A1-ITGA11+ITGB1COGA1_HUMAN - Adhesion-AdhesionAdhesion by Collagen/Integrin
5COL16A1-ITGA1+ITGB1COGA1_HUMAN - Adhesion-AdhesionAdhesion by Collagen/Integrin
6COL16A1-ITGA2+ITGB1COGA1_HUMAN - Adhesion-AdhesionAdhesion by Collagen/Integrin
7COL3A1-ITGA10+ITGB1CO3A1_HUMAN - Adhesion-AdhesionAdhesion by Collagen/Integrin
8COL3A1-ITGA11+ITGB1CO3A1_HUMAN - Adhesion-AdhesionAdhesion by Collagen/Integrin
9COL3A1-ITGA1+ITGB1CO3A1_HUMAN - Adhesion-AdhesionAdhesion by Collagen/Integrin
10COL3A1-ITGA2+ITGB1CO3A1_HUMAN - Adhesion-AdhesionAdhesion by Collagen/Integrin
11FN1-ITGA10+ITGB1FINC_HUMAN - Adhesion-AdhesionAdhesion by Fibronectin
12FN1-ITGA11+ITGB1FINC_HUMAN - Adhesion-AdhesionAdhesion by Fibronectin
13FN1-ITGA2B+ITGB3FINC_HUMAN - Adhesion-AdhesionAdhesion by Fibronectin
14FN1-ITGA2+ITGB1FINC_HUMAN - Adhesion-AdhesionAdhesion by Fibronectin
15FN1-ITGA3+ITGB1FINC_HUMAN - Adhesion-AdhesionAdhesion by Fibronectin
16FN1-ITGA4+ITGB1FINC_HUMAN - Adhesion-AdhesionAdhesion by Fibronectin
17FN1-ITGA4+ITGB7FINC_HUMAN - Adhesion-AdhesionAdhesion by Fibronectin
18FN1-ITGA5+ITGB1FINC_HUMAN - Adhesion-AdhesionAdhesion by Fibronectin
19FN1-ITGA8+ITGB1FINC_HUMAN - Adhesion-AdhesionAdhesion by Fibronectin
20FN1-ITGAV+ITGB1FINC_HUMAN - Adhesion-AdhesionAdhesion by Fibronectin
21FN1-ITGAV+ITGB3FINC_HUMAN - Adhesion-AdhesionAdhesion by Fibronectin
22FN1-ITGAV+ITGB5FINC_HUMAN - Adhesion-AdhesionAdhesion by Fibronectin
23MADCAM1-ITGA4+ITGB7MADCA_HUMAN - Adhesion-Adhesion
24SEMA7A-ITGA1+ITGB1SEM7A_HUMAN - Ligand-ReceptorSignaling by Semaphorin
25THY1-ITGAM+ITGB2THY1_HUMAN - Adhesion-AdhesionAdhesion by antigen THY1
26THY1-ITGAV+ITGB3THY1_HUMAN - Adhesion-AdhesionAdhesion by antigen THY1
27THY1-ITGAX+ITGB2THY1_HUMAN - Adhesion-AdhesionAdhesion by antigen THY1

II. Literature review

[source]
Nameintegrin-mediated signaling pathway
IDGO_0007229
collection_id

Biological process

Exact synonym

integrin-mediated signalling pathway

Description

The series of molecular signals initiated by an extracellular ligand binding to an integrin on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.

External URL
Genes
ITGA2THY1TECITGBL1LATITGA8DIAPH3intg_a2_b1_humanANGPTL3CUL3DAB2intg_a10_b1_humanITGA2Bintg_a4_b1_humanFERMT1CCN2ADAMTS1FERMT2CCM2ITGAVDSTDOCK1ZNF304PTPRAADAM15ITGA6HCKintg_a6_b1_humanITGA11ADAMTS13COL3A1intg_av_b6_humanITGA10PTK2intg_a2b_b3_humanMADCAM1intg_a3_b3_humanSYKMPIG6BITGAMITGADADAM9ITGAERCC2ITGB4ITGA9intg_a5_b1_humanSRCCD47ADAM10CDC42intg_av_b3_humanCTNNA1ISG15SEMA7ANME2ILKFGRITGA5ITGB8ITGA3intg_a9_b1_humanITGB2ITGB3VAV1intg_a1_b1_humanintg_av_b8_humanintg_am_b2_humanCOL16A1intg_av_b5_humanERBINITGB1FYB2FN1TLN1NEDD9FUT8intg_a4_b7_humanITGAXLIMS2BCAR1PTPN11FBLN1ITGB6PRAM1PTK2BFYB1PRKD1ITGA7PTNNRP1PLPP3ADAM11FERMT3ITGB1BP1CD40LGCEACAM1ITGB7APOA1ITGALPLEKVAV3intg_al_b2_humanCDH17ABL1TSPAN32intg_ax_b2_humanITGA4intg_av_b1_humanZYXITGA1MYH9LAMA5ITGB5