Name | Number of supported studies | Average coverage | |
---|---|---|---|
classical monocyte | 25 studies | 31% ± 15% | |
conventional dendritic cell | 23 studies | 31% ± 17% | |
non-classical monocyte | 23 studies | 41% ± 19% | |
macrophage | 21 studies | 31% ± 11% | |
monocyte | 14 studies | 34% ± 11% | |
dendritic cell | 12 studies | 33% ± 13% | |
microglial cell | 12 studies | 37% ± 16% | |
myeloid cell | 11 studies | 42% ± 18% | |
CD16-negative, CD56-bright natural killer cell, human | 10 studies | 34% ± 20% | |
mast cell | 9 studies | 22% ± 11% | |
neutrophil | 9 studies | 32% ± 10% | |
natural killer cell | 8 studies | 25% ± 11% | |
CD16-positive, CD56-dim natural killer cell, human | 7 studies | 28% ± 9% | |
alveolar macrophage | 6 studies | 33% ± 11% | |
mononuclear phagocyte | 4 studies | 29% ± 11% | |
B cell | 3 studies | 17% ± 2% | |
leukocyte | 3 studies | 32% ± 17% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
peripheral blood | 4 studies | 26% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 17278.67 | 578 / 578 | 96% | 18.72 | 1104 / 1155 |
breast | 51% | 1069.48 | 232 / 459 | 94% | 11.62 | 1054 / 1118 |
brain | 49% | 998.62 | 1301 / 2642 | 94% | 16.09 | 660 / 705 |
kidney | 46% | 690.60 | 41 / 89 | 92% | 16.28 | 825 / 901 |
prostate | 62% | 1016.20 | 153 / 245 | 66% | 4.39 | 333 / 502 |
thymus | 47% | 785.06 | 306 / 653 | 77% | 7.83 | 463 / 605 |
liver | 59% | 959.42 | 134 / 226 | 59% | 5.09 | 240 / 406 |
intestine | 45% | 773.99 | 437 / 966 | 72% | 8.69 | 380 / 527 |
uterus | 31% | 388.59 | 53 / 170 | 81% | 8.09 | 374 / 459 |
esophagus | 28% | 351.68 | 405 / 1445 | 83% | 9.18 | 152 / 183 |
stomach | 28% | 446.70 | 101 / 359 | 81% | 10.67 | 231 / 286 |
pancreas | 16% | 263.02 | 52 / 328 | 90% | 16.02 | 161 / 178 |
bladder | 38% | 1218.38 | 8 / 21 | 67% | 8.64 | 336 / 504 |
skin | 7% | 72.50 | 132 / 1809 | 93% | 15.48 | 441 / 472 |
lymph node | 0% | 0 | 0 / 0 | 100% | 60.95 | 29 / 29 |
spleen | 100% | 22344.60 | 241 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 94% | 45485.10 | 873 / 929 | 0% | 0 | 0 / 0 |
ovary | 13% | 143.88 | 24 / 180 | 73% | 6.37 | 313 / 430 |
tonsil | 0% | 0 | 0 / 0 | 84% | 12.56 | 38 / 45 |
adipose | 80% | 2409.24 | 958 / 1204 | 0% | 0 | 0 / 0 |
adrenal gland | 36% | 488.63 | 94 / 258 | 33% | 2.44 | 75 / 230 |
eye | 0% | 0 | 0 / 0 | 51% | 6.38 | 41 / 80 |
blood vessel | 45% | 1174.87 | 601 / 1335 | 0% | 0 | 0 / 0 |
heart | 26% | 427.78 | 228 / 861 | 0% | 0 | 0 / 0 |
muscle | 1% | 11.80 | 10 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0033627 | Biological process | cell adhesion mediated by integrin |
GO_0045766 | Biological process | positive regulation of angiogenesis |
GO_0007160 | Biological process | cell-matrix adhesion |
GO_0009887 | Biological process | animal organ morphogenesis |
GO_0051607 | Biological process | defense response to virus |
GO_0010628 | Biological process | positive regulation of gene expression |
GO_0007155 | Biological process | cell adhesion |
GO_0034113 | Biological process | heterotypic cell-cell adhesion |
GO_0007229 | Biological process | integrin-mediated signaling pathway |
GO_0030335 | Biological process | positive regulation of cell migration |
GO_0008284 | Biological process | positive regulation of cell population proliferation |
GO_0031643 | Biological process | positive regulation of myelination |
GO_1905956 | Biological process | positive regulation of endothelial tube morphogenesis |
GO_0098609 | Biological process | cell-cell adhesion |
GO_0030667 | Cellular component | secretory granule membrane |
GO_0009897 | Cellular component | external side of plasma membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0008305 | Cellular component | integrin complex |
GO_0034689 | Cellular component | integrin alphaX-beta2 complex |
GO_0009986 | Cellular component | cell surface |
GO_0070821 | Cellular component | tertiary granule membrane |
GO_0101003 | Cellular component | ficolin-1-rich granule membrane |
GO_0038023 | Molecular function | signaling receptor activity |
GO_0005178 | Molecular function | integrin binding |
GO_0046872 | Molecular function | metal ion binding |
GO_0005515 | Molecular function | protein binding |
GO_0030971 | Molecular function | receptor tyrosine kinase binding |
Gene name | ITGAX |
Protein name | Integrin alpha-X (CD11 antigen-like family member C) (Leu M5) (Leukocyte adhesion glycoprotein p150,95 alpha chain) (Leukocyte adhesion receptor p150,95) (CD antigen CD11c) Integrin subunit alpha X |
Synonyms | CD11C |
Description | FUNCTION: Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. |
Accessions | H3BN02 P20702 ENST00000268296.9 ENST00000562918.5 ENST00000562522.2 A0A087X131 |