Name | Number of supported studies | Average coverage | |
---|---|---|---|
smooth muscle cell | 16 studies | 37% ± 19% | |
fibroblast | 15 studies | 36% ± 12% | |
connective tissue cell | 7 studies | 22% ± 5% | |
oligodendrocyte precursor cell | 7 studies | 43% ± 10% | |
pericyte | 7 studies | 45% ± 23% | |
myofibroblast cell | 6 studies | 28% ± 12% | |
GABAergic neuron | 5 studies | 24% ± 8% | |
glomerular endothelial cell | 4 studies | 47% ± 3% | |
endothelial cell | 4 studies | 21% ± 6% | |
endothelial cell of vascular tree | 3 studies | 26% ± 4% | |
interneuron | 3 studies | 29% ± 9% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 3 studies | 22% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 82% | 6769.84 | 202 / 245 | 96% | 22.49 | 481 / 502 |
lung | 97% | 7444.30 | 562 / 578 | 70% | 5.58 | 808 / 1155 |
bladder | 86% | 5953.62 | 18 / 21 | 48% | 2.64 | 244 / 504 |
adrenal gland | 62% | 1776.31 | 159 / 258 | 71% | 5.06 | 163 / 230 |
kidney | 63% | 1889.52 | 56 / 89 | 69% | 11.22 | 624 / 901 |
thymus | 63% | 1895.17 | 410 / 653 | 67% | 3.29 | 408 / 605 |
esophagus | 70% | 10795.26 | 1010 / 1445 | 59% | 5.14 | 108 / 183 |
uterus | 83% | 3301.04 | 141 / 170 | 46% | 11.99 | 210 / 459 |
stomach | 73% | 6044.01 | 262 / 359 | 53% | 5.28 | 151 / 286 |
ureter | 0% | 0 | 0 / 0 | 100% | 2.54 | 1 / 1 |
blood vessel | 100% | 64925.59 | 1333 / 1335 | 0% | 0 | 0 / 0 |
spleen | 92% | 3723.04 | 221 / 241 | 0% | 0 | 0 / 0 |
breast | 20% | 627.42 | 91 / 459 | 65% | 3.11 | 730 / 1118 |
intestine | 26% | 670.83 | 249 / 966 | 46% | 3.12 | 244 / 527 |
pancreas | 1% | 10.23 | 2 / 328 | 63% | 3.31 | 112 / 178 |
tonsil | 0% | 0 | 0 / 0 | 44% | 1.76 | 20 / 45 |
adipose | 42% | 1866.87 | 510 / 1204 | 0% | 0 | 0 / 0 |
brain | 2% | 45.19 | 56 / 2642 | 36% | 1.81 | 257 / 705 |
skin | 16% | 409.71 | 289 / 1809 | 21% | 2.72 | 99 / 472 |
ovary | 28% | 1536.73 | 50 / 180 | 7% | 0.44 | 32 / 430 |
heart | 23% | 559.57 | 197 / 861 | 0% | 0 | 0 / 0 |
liver | 0% | 6.48 | 1 / 226 | 11% | 0.46 | 45 / 406 |
muscle | 6% | 158.08 | 51 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 5% | 0.21 | 4 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0030511 | Biological process | positive regulation of transforming growth factor beta receptor signaling pathway |
GO_0033627 | Biological process | cell adhesion mediated by integrin |
GO_0007160 | Biological process | cell-matrix adhesion |
GO_0045184 | Biological process | establishment of protein localization |
GO_0001656 | Biological process | metanephros development |
GO_0030198 | Biological process | extracellular matrix organization |
GO_0001822 | Biological process | kidney development |
GO_0030030 | Biological process | cell projection organization |
GO_0048333 | Biological process | mesodermal cell differentiation |
GO_0007229 | Biological process | integrin-mediated signaling pathway |
GO_0034446 | Biological process | substrate adhesion-dependent cell spreading |
GO_0051145 | Biological process | smooth muscle cell differentiation |
GO_0042472 | Biological process | inner ear morphogenesis |
GO_0007613 | Biological process | memory |
GO_0098609 | Biological process | cell-cell adhesion |
GO_0007179 | Biological process | transforming growth factor beta receptor signaling pathway |
GO_0007399 | Biological process | nervous system development |
GO_0048745 | Biological process | smooth muscle tissue development |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0098839 | Cellular component | postsynaptic density membrane |
GO_0009897 | Cellular component | external side of plasma membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0043204 | Cellular component | perikaryon |
GO_0008305 | Cellular component | integrin complex |
GO_0005925 | Cellular component | focal adhesion |
GO_0009986 | Cellular component | cell surface |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0032591 | Cellular component | dendritic spine membrane |
GO_0034678 | Cellular component | integrin alpha8-beta1 complex |
GO_0045177 | Cellular component | apical part of cell |
GO_0005178 | Molecular function | integrin binding |
GO_0046872 | Molecular function | metal ion binding |
Gene name | ITGA8 |
Protein name | Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain] |
Synonyms | |
Description | FUNCTION: Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons. . |
Accessions | P53708 ENST00000378076.4 |