Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 3950.35 | 578 / 578 | 94% | 39.05 | 1085 / 1155 |
breast | 87% | 976.95 | 400 / 459 | 93% | 33.27 | 1044 / 1118 |
bladder | 95% | 836.76 | 20 / 21 | 64% | 21.08 | 324 / 504 |
intestine | 82% | 944.35 | 793 / 966 | 71% | 19.75 | 373 / 527 |
thymus | 59% | 513.94 | 383 / 653 | 74% | 18.26 | 450 / 605 |
stomach | 49% | 423.92 | 177 / 359 | 78% | 28.44 | 223 / 286 |
kidney | 42% | 371.46 | 37 / 89 | 84% | 30.39 | 758 / 901 |
brain | 40% | 394.80 | 1069 / 2642 | 83% | 22.46 | 583 / 705 |
esophagus | 51% | 417.53 | 743 / 1445 | 70% | 13.76 | 129 / 183 |
uterus | 39% | 241.54 | 66 / 170 | 75% | 19.34 | 342 / 459 |
adrenal gland | 75% | 646.46 | 194 / 258 | 30% | 4.24 | 70 / 230 |
liver | 56% | 409.35 | 126 / 226 | 49% | 10.39 | 199 / 406 |
skin | 20% | 109.93 | 357 / 1809 | 83% | 36.29 | 390 / 472 |
lymph node | 0% | 0 | 0 / 0 | 100% | 362.07 | 29 / 29 |
peripheral blood | 100% | 27673.58 | 929 / 929 | 0% | 0 | 0 / 0 |
spleen | 100% | 9459.80 | 241 / 241 | 0% | 0 | 0 / 0 |
ovary | 21% | 132.18 | 38 / 180 | 77% | 16.66 | 333 / 430 |
prostate | 46% | 335.76 | 113 / 245 | 52% | 7.47 | 262 / 502 |
adipose | 97% | 2000.80 | 1170 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 91% | 53.39 | 41 / 45 |
pancreas | 10% | 59.61 | 33 / 328 | 79% | 19.80 | 140 / 178 |
blood vessel | 57% | 675.60 | 759 / 1335 | 0% | 0 | 0 / 0 |
heart | 37% | 243.25 | 317 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 21% | 3.77 | 17 / 80 |
muscle | 7% | 32.64 | 53 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0002244 | Biological process | hematopoietic progenitor cell differentiation |
GO_0046488 | Biological process | phosphatidylinositol metabolic process |
GO_0031529 | Biological process | ruffle organization |
GO_0010925 | Biological process | positive regulation of inositol-polyphosphate 5-phosphatase activity |
GO_0010920 | Biological process | negative regulation of inositol phosphate biosynthetic process |
GO_0070527 | Biological process | platelet aggregation |
GO_0070560 | Biological process | protein secretion by platelet |
GO_0032233 | Biological process | positive regulation of actin filament bundle assembly |
GO_0002576 | Biological process | platelet degranulation |
GO_0030845 | Biological process | phospholipase C-inhibiting G protein-coupled receptor signaling pathway |
GO_0070493 | Biological process | thrombin-activated receptor signaling pathway |
GO_0030030 | Biological process | cell projection organization |
GO_0060305 | Biological process | regulation of cell diameter |
GO_0045744 | Biological process | negative regulation of G protein-coupled receptor signaling pathway |
GO_0030036 | Biological process | actin cytoskeleton organization |
GO_0006904 | Biological process | vesicle docking involved in exocytosis |
GO_0007229 | Biological process | integrin-mediated signaling pathway |
GO_0050849 | Biological process | negative regulation of calcium-mediated signaling |
GO_0070528 | Biological process | protein kinase C signaling |
GO_0030836 | Biological process | positive regulation of actin filament depolymerization |
GO_0010572 | Biological process | positive regulation of platelet activation |
GO_0033625 | Biological process | positive regulation of integrin activation |
GO_0030866 | Biological process | cortical actin cytoskeleton organization |
GO_0032587 | Cellular component | ruffle membrane |
GO_0005576 | Cellular component | extracellular region |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0005080 | Molecular function | protein kinase C binding |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0005515 | Molecular function | protein binding |
GO_0043325 | Molecular function | phosphatidylinositol-3,4-bisphosphate binding |
Gene name | PLEK |
Protein name | Pleckstrin (Platelet 47 kDa protein) (p47) |
Synonyms | P47 |
Description | FUNCTION: Major protein kinase C substrate of platelets. |
Accessions | ENST00000234313.8 P08567 |