Biological process

down regulation of G-protein coupled receptor protein signaling pathway, down-regulation of G-protein coupled receptor protein signaling pathway, downregulation of G-protein coupled receptor protein signaling pathway, negative regulation of G protein coupled receptor protein signaling pathway, negative regulation of G protein coupled receptor protein signalling pathway, negative regulation of G-protein coupled receptor protein signaling pathway, negative regulation of G-protein coupled receptor protein signalling pathway, negative regulation of G-protein-coupled receptor protein signalling pathway, negative regulation of GPCR protein signaling pathway, negative regulation of GPCR protein signalling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway.