ADRB3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ADRB3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ADRB3 at tissue level.

III. Associated gene sets

GO_0050873Biological processbrown fat cell differentiation
GO_0006091Biological processgeneration of precursor metabolites and energy
GO_0007188Biological processadenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO_0071880Biological processadenylate cyclase-activating adrenergic receptor signaling pathway
GO_0006898Biological processreceptor-mediated endocytosis
GO_0005975Biological processcarbohydrate metabolic process
GO_0002024Biological processdiet induced thermogenesis
GO_0043410Biological processpositive regulation of MAPK cascade
GO_0040015Biological processnegative regulation of multicellular organism growth
GO_0002025Biological processnorepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
GO_0045744Biological processnegative regulation of G protein-coupled receptor signaling pathway
GO_0009409Biological processresponse to cold
GO_0042755Biological processeating behavior
GO_0031649Biological processheat generation
GO_0120162Biological processpositive regulation of cold-induced thermogenesis
GO_0007187Biological processG protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO_0006112Biological processenergy reserve metabolic process
GO_0043235Cellular componentreceptor complex
GO_0005886Cellular componentplasma membrane
GO_0042803Molecular functionprotein homodimerization activity
GO_0031699Molecular functionbeta-3 adrenergic receptor binding
GO_0015052Molecular functionbeta3-adrenergic receptor activity
GO_0051380Molecular functionnorepinephrine binding
GO_0004939Molecular functionbeta-adrenergic receptor activity
GO_0051379Molecular functionepinephrine binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameADRB3
Protein nameBeta-3 adrenergic receptor (Beta-3 adrenoreceptor)
Beta-3 adrenergic receptor (Beta-3 adrenoreceptor) (Beta-3 adrenoceptor)
SynonymsB3AR
ADRB3R
hCG_21141
DescriptionFUNCTION: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.

FUNCTION: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis. .

FUNCTION: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis. .

FUNCTION: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis. .

AccessionsB8X6N1
P13945
A8KAG8
ENST00000345060.5
B8X6N0