Name | Number of supported studies | Average coverage | |
---|---|---|---|
conventional dendritic cell | 6 studies | 31% ± 16% | |
epithelial cell | 6 studies | 32% ± 13% | |
hematopoietic precursor cell | 5 studies | 26% ± 7% | |
microglial cell | 5 studies | 25% ± 8% | |
basal cell | 5 studies | 27% ± 8% | |
macrophage | 5 studies | 25% ± 5% | |
endothelial cell | 4 studies | 23% ± 6% | |
ciliated cell | 3 studies | 24% ± 5% | |
dendritic cell | 3 studies | 44% ± 20% | |
transit amplifying cell | 3 studies | 29% ± 14% | |
neuron | 3 studies | 20% ± 4% | |
glutamatergic neuron | 3 studies | 22% ± 9% | |
oligodendrocyte precursor cell | 3 studies | 29% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 3561.20 | 180 / 180 | 100% | 168.21 | 430 / 430 |
esophagus | 100% | 4634.47 | 1444 / 1445 | 100% | 191.57 | 183 / 183 |
breast | 100% | 3990.00 | 459 / 459 | 100% | 164.21 | 1116 / 1118 |
intestine | 100% | 3647.35 | 966 / 966 | 100% | 142.69 | 525 / 527 |
bladder | 100% | 3273.81 | 21 / 21 | 100% | 157.43 | 502 / 504 |
skin | 100% | 7633.06 | 1809 / 1809 | 100% | 206.80 | 470 / 472 |
lung | 100% | 4137.18 | 578 / 578 | 100% | 152.33 | 1150 / 1155 |
uterus | 100% | 3129.05 | 170 / 170 | 99% | 209.50 | 455 / 459 |
stomach | 100% | 2398.47 | 358 / 359 | 99% | 139.58 | 284 / 286 |
prostate | 100% | 3725.06 | 245 / 245 | 96% | 80.87 | 481 / 502 |
thymus | 100% | 3377.38 | 653 / 653 | 96% | 81.08 | 579 / 605 |
brain | 97% | 2061.48 | 2569 / 2642 | 97% | 82.11 | 685 / 705 |
pancreas | 98% | 2043.58 | 322 / 328 | 96% | 103.59 | 170 / 178 |
kidney | 99% | 2603.97 | 88 / 89 | 85% | 53.01 | 770 / 901 |
adrenal gland | 100% | 2833.88 | 258 / 258 | 45% | 19.58 | 103 / 230 |
liver | 91% | 1302.21 | 206 / 226 | 37% | 22.94 | 151 / 406 |
adipose | 100% | 3048.53 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 160.38 | 29 / 29 |
spleen | 100% | 6253.67 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 252.59 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 110.29 | 1 / 1 |
eye | 0% | 0 | 0 / 0 | 98% | 104.12 | 78 / 80 |
blood vessel | 95% | 1701.39 | 1265 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 91% | 4100.44 | 843 / 929 | 0% | 0 | 0 / 0 |
heart | 85% | 1197.68 | 736 / 861 | 0% | 0 | 0 / 0 |
muscle | 50% | 585.71 | 404 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0034260 | Biological process | negative regulation of GTPase activity |
GO_0010971 | Biological process | positive regulation of G2/M transition of mitotic cell cycle |
GO_0045184 | Biological process | establishment of protein localization |
GO_0051895 | Biological process | negative regulation of focal adhesion assembly |
GO_0051301 | Biological process | cell division |
GO_0051987 | Biological process | positive regulation of attachment of spindle microtubules to kinetochore |
GO_0072356 | Biological process | chromosome passenger complex localization to kinetochore |
GO_0007229 | Biological process | integrin-mediated signaling pathway |
GO_0030334 | Biological process | regulation of cell migration |
GO_0048041 | Biological process | focal adhesion assembly |
GO_1900025 | Biological process | negative regulation of substrate adhesion-dependent cell spreading |
GO_0010762 | Biological process | regulation of fibroblast migration |
GO_1900027 | Biological process | regulation of ruffle assembly |
GO_0005730 | Cellular component | nucleolus |
GO_0030496 | Cellular component | midbody |
GO_0005886 | Cellular component | plasma membrane |
GO_0005874 | Cellular component | microtubule |
GO_0016020 | Cellular component | membrane |
GO_0031901 | Cellular component | early endosome membrane |
GO_1990023 | Cellular component | mitotic spindle midzone |
GO_0034506 | Cellular component | chromosome, centromeric core domain |
GO_0005829 | Cellular component | cytosol |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0019904 | Molecular function | protein domain specific binding |
GO_0019901 | Molecular function | protein kinase binding |
GO_0031267 | Molecular function | small GTPase binding |
GO_0008017 | Molecular function | microtubule binding |
GO_0003723 | Molecular function | RNA binding |
GO_0005515 | Molecular function | protein binding |
Gene name | RCC2 |
Protein name | Protein RCC2 (RCC1-like protein TD-60) (Telophase disk protein of 60 kDa) RCC2 protein Epididymis secretory sperm binding protein (Regulator of chromosome condensation 2, isoform CRA_a) |
Synonyms | KIAA1470 TD60 hCG_25129 |
Description | FUNCTION: Multifunctional protein that may affect its functions by regulating the activity of small GTPases, such as RAC1 and RALA . Required for normal progress through the cell cycle, both during interphase and during mitosis . Required for the presence of normal levels of MAD2L1, AURKB and BIRC5 on inner centromeres during mitosis, and for normal attachment of kinetochores to mitotic spindles . Required for normal organization of the microtubule cytoskeleton in interphase cells . Functions as guanine nucleotide exchange factor (GEF) for RALA . Interferes with the activation of RAC1 by guanine nucleotide exchange factors . Prevents accumulation of active, GTP-bound RAC1, and suppresses RAC1-mediated reorganization of the actin cytoskeleton and formation of membrane protrusions . Required for normal cellular responses to contacts with the extracellular matrix of adjacent cells, and for directional cell migration in response to a fibronectin gradient (in vitro) . . |
Accessions | ENST00000375433.3 A0A024RAC5 ENST00000375436.9 A5PLK7 ENST00000628984.1 Q9P258 ENST00000631021.3 |