ITGAE report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
B cell	21 studies	27% ± 10%	Explore
natural killer cell	19 studies	21% ± 6%	Explore
plasmacytoid dendritic cell	16 studies	29% ± 10%	Explore
CD8-positive, alpha-beta T cell	14 studies	23% ± 7%	Explore
memory B cell	12 studies	19% ± 2%	Explore
naive B cell	12 studies	19% ± 3%	Explore
T cell	10 studies	29% ± 6%	Explore
CD4-positive, alpha-beta T cell	9 studies	24% ± 6%	Explore
gamma-delta T cell	8 studies	35% ± 17%	Explore
CD8-positive, alpha-beta memory T cell	7 studies	27% ± 10%	Explore
classical monocyte	7 studies	26% ± 11%	Explore
fibroblast	7 studies	23% ± 8%	Explore
plasmablast	6 studies	40% ± 22%	Explore
regulatory T cell	6 studies	24% ± 4%	Explore
hematopoietic precursor cell	5 studies	30% ± 14%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	18% ± 1%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	19% ± 3%	Explore
CD16-positive, CD56-dim natural killer cell, human	5 studies	20% ± 3%	Explore
mature NK T cell	5 studies	24% ± 9%	Explore
precursor B cell	5 studies	38% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	24% ± 7%	Explore
immature B cell	5 studies	32% ± 16%	Explore
plasma cell	4 studies	30% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	21% ± 4%	Explore
exhausted T cell	4 studies	27% ± 7%	Explore
epithelial cell	4 studies	42% ± 14%	Explore
endothelial cell	4 studies	24% ± 8%	Explore
ciliated cell	4 studies	33% ± 7%	Explore
dendritic cell	4 studies	31% ± 19%	Explore
abnormal cell	4 studies	20% ± 2%	Explore
leukocyte	3 studies	24% ± 8%	Explore
conventional dendritic cell	3 studies	43% ± 16%	Explore
monocyte	3 studies	19% ± 5%	Explore
smooth muscle cell	3 studies	32% ± 8%	Explore
lymphocyte	3 studies	29% ± 8%	Explore
myeloid cell	3 studies	27% ± 6%	Explore
pro-B cell	3 studies	22% ± 3%	Explore
intraepithelial lymphocyte	3 studies	33% ± 10%	Explore
T follicular helper cell	3 studies	18% ± 2%	Explore
germinal center B cell	3 studies	34% ± 5%	Explore
GABAergic neuron	3 studies	21% ± 6%	Explore
glutamatergic neuron	3 studies	28% ± 6%	Explore
T-helper 17 cell	3 studies	23% ± 6%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	22% ± 4%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	6 studies	25% ± 12%	Explore
lung	5 studies	24% ± 8%	Explore
brain	4 studies	19% ± 3%	Explore
lymph node	3 studies	16% ± 1%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	837.33	2641 / 2642	100%	9.84	705 / 705
lung	100%	1068.06	578 / 578	100%	9.81	1154 / 1155
intestine	100%	935.75	966 / 966	100%	7.82	526 / 527
stomach	100%	681.11	359 / 359	100%	8.02	285 / 286
uterus	100%	752.95	170 / 170	100%	10.65	457 / 459
esophagus	100%	816.59	1445 / 1445	99%	8.33	182 / 183
prostate	100%	892.20	245 / 245	99%	6.79	499 / 502
breast	100%	845.54	459 / 459	99%	7.58	1111 / 1118
bladder	100%	856.33	21 / 21	99%	8.60	500 / 504
thymus	100%	715.49	653 / 653	99%	7.29	598 / 605
skin	100%	678.89	1806 / 1809	98%	7.48	462 / 472
ovary	100%	700.33	180 / 180	97%	5.09	418 / 430
pancreas	97%	296.80	317 / 328	99%	7.05	177 / 178
adrenal gland	100%	920.21	258 / 258	93%	4.68	215 / 230
kidney	100%	721.57	89 / 89	93%	5.18	836 / 901
liver	98%	278.50	221 / 226	66%	3.53	266 / 406
adipose	100%	927.38	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	17.66	29 / 29
spleen	100%	1290.59	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	15.12	45 / 45
ureter	0%	0	0 / 0	100%	2.88	1 / 1
muscle	100%	752.96	799 / 803	0%	0	0 / 0
blood vessel	99%	592.10	1328 / 1335	0%	0	0 / 0
heart	98%	522.11	840 / 861	0%	0	0 / 0
peripheral blood	94%	437.26	873 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	79%	3.92	63 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0