ADAMTS13 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ADAMTS13 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ADAMTS13 at tissue level.

III. Associated gene sets

GO_0014075Biological processresponse to amine
GO_0035864Biological processresponse to potassium ion
GO_0007160Biological processcell-matrix adhesion
GO_0030198Biological processextracellular matrix organization
GO_0016485Biological processprotein processing
GO_0007596Biological processblood coagulation
GO_0071353Biological processcellular response to interleukin-4
GO_0030168Biological processplatelet activation
GO_0071356Biological processcellular response to tumor necrosis factor
GO_0007229Biological processintegrin-mediated signaling pathway
GO_0009100Biological processglycoprotein metabolic process
GO_0006508Biological processproteolysis
GO_0030163Biological processprotein catabolic process
GO_0071222Biological processcellular response to lipopolysaccharide
GO_0009636Biological processresponse to toxic substance
GO_0043171Biological processpeptide catabolic process
GO_0071346Biological processcellular response to type II interferon
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0031012Cellular componentextracellular matrix
GO_0009986Cellular componentcell surface
GO_0005788Cellular componentendoplasmic reticulum lumen
GO_0008237Molecular functionmetallopeptidase activity
GO_0005178Molecular functionintegrin binding
GO_0008270Molecular functionzinc ion binding
GO_0004222Molecular functionmetalloendopeptidase activity
GO_0005509Molecular functioncalcium ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameADAMTS13
Protein nameADAMTS13
von Willebrand factor-cleaving protease
ADAM metallopeptidase with thrombospondin type 1 motif 13 (EC 3.4.24.-)
ADAM metallopeptidase with thrombospondin type 1 motif 13
A disintegrin and metalloproteinase with thrombospondin motifs 13 (ADAM-TS 13) (ADAM-TS13) (ADAMTS-13) (EC 3.4.24.87) (von Willebrand factor-cleaving protease) (vWF-CP) (vWF-cleaving protease)
SynonymsC9orf8
UNQ6102/PRO20085
DescriptionFUNCTION: Cleaves the vWF multimers in plasma into smaller forms thereby controlling vWF-mediated platelet thrombus formation. .

AccessionsENST00000626597.2 [Q76LX8-1]
A0A0B4J229
ENST00000371916.5
F6V803
ENST00000371911.7
ENST00000356589.6 [Q76LX8-3]
Q6QNA7
ENST00000371929.7 [Q76LX8-1]
Q6QNA6
A0A2D0ZBS7
ENST00000355699.7 [Q76LX8-2]
Q6QNA4
ENST00000630465.2 [Q76LX8-3]
ENST00000371910.1
Q76LX8
E7EV88
Q6QNA5
ENST00000626744.2 [Q76LX8-2]
Q96P40
ENST00000474918.1
ENST00000495234.5
A0A0C4DFV8
D5KRM8