Name | Number of supported studies | Average coverage | |
---|---|---|---|
microglial cell | 10 studies | 32% ± 13% | |
macrophage | 10 studies | 32% ± 14% | |
non-classical monocyte | 8 studies | 24% ± 10% | |
mast cell | 7 studies | 29% ± 11% | |
myeloid cell | 5 studies | 27% ± 6% | |
dendritic cell | 5 studies | 20% ± 5% | |
T cell | 4 studies | 19% ± 3% | |
monocyte | 4 studies | 25% ± 9% | |
classical monocyte | 3 studies | 27% ± 5% | |
B cell | 3 studies | 20% ± 0% | |
lymphocyte | 3 studies | 30% ± 9% | |
brush cell | 3 studies | 41% ± 17% | |
plasmacytoid dendritic cell | 3 studies | 23% ± 5% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
peripheral blood | 3 studies | 18% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 1515.82 | 578 / 578 | 92% | 14.97 | 1060 / 1155 |
breast | 90% | 353.38 | 413 / 459 | 89% | 10.19 | 997 / 1118 |
stomach | 83% | 282.77 | 297 / 359 | 82% | 8.94 | 235 / 286 |
bladder | 90% | 423.29 | 19 / 21 | 70% | 7.92 | 355 / 504 |
intestine | 87% | 753.54 | 844 / 966 | 73% | 6.90 | 383 / 527 |
prostate | 93% | 393.12 | 228 / 245 | 55% | 3.35 | 275 / 502 |
brain | 58% | 213.07 | 1541 / 2642 | 86% | 10.01 | 606 / 705 |
esophagus | 80% | 262.99 | 1150 / 1445 | 63% | 4.94 | 116 / 183 |
kidney | 57% | 246.70 | 51 / 89 | 81% | 9.08 | 734 / 901 |
thymus | 73% | 290.96 | 476 / 653 | 64% | 15.03 | 388 / 605 |
uterus | 56% | 147.59 | 96 / 170 | 77% | 7.81 | 352 / 459 |
adrenal gland | 92% | 413.71 | 238 / 258 | 26% | 1.73 | 60 / 230 |
skin | 38% | 90.19 | 686 / 1809 | 70% | 10.42 | 331 / 472 |
pancreas | 22% | 59.70 | 72 / 328 | 86% | 14.18 | 153 / 178 |
ovary | 24% | 61.18 | 43 / 180 | 77% | 7.68 | 330 / 430 |
lymph node | 0% | 0 | 0 / 0 | 100% | 108.18 | 29 / 29 |
peripheral blood | 100% | 10154.98 | 929 / 929 | 0% | 0 | 0 / 0 |
spleen | 100% | 5989.43 | 241 / 241 | 0% | 0 | 0 / 0 |
liver | 62% | 177.50 | 139 / 226 | 38% | 3.28 | 153 / 406 |
adipose | 98% | 635.16 | 1175 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 91% | 13.97 | 41 / 45 |
blood vessel | 62% | 294.97 | 822 / 1335 | 0% | 0 | 0 / 0 |
heart | 33% | 85.48 | 285 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 23% | 1.59 | 18 / 80 |
muscle | 4% | 6.71 | 29 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0071466 | Biological process | cellular response to xenobiotic stimulus |
GO_0045954 | Biological process | positive regulation of natural killer cell mediated cytotoxicity |
GO_0031295 | Biological process | T cell costimulation |
GO_0051056 | Biological process | regulation of small GTPase mediated signal transduction |
GO_0030593 | Biological process | neutrophil chemotaxis |
GO_0038095 | Biological process | Fc-epsilon receptor signaling pathway |
GO_0030168 | Biological process | platelet activation |
GO_0072593 | Biological process | reactive oxygen species metabolic process |
GO_0042267 | Biological process | natural killer cell mediated cytotoxicity |
GO_0030217 | Biological process | T cell differentiation |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0007229 | Biological process | integrin-mediated signaling pathway |
GO_0035556 | Biological process | intracellular signal transduction |
GO_0043087 | Biological process | regulation of GTPase activity |
GO_0048010 | Biological process | vascular endothelial growth factor receptor signaling pathway |
GO_0008361 | Biological process | regulation of cell size |
GO_0016477 | Biological process | cell migration |
GO_0038096 | Biological process | Fc-gamma receptor signaling pathway involved in phagocytosis |
GO_0005886 | Cellular component | plasma membrane |
GO_0005911 | Cellular component | cell-cell junction |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0140031 | Molecular function | phosphorylation-dependent protein binding |
GO_0005515 | Molecular function | protein binding |
GO_0001784 | Molecular function | phosphotyrosine residue binding |
Gene name | VAV1 |
Protein name | Alternative protein VAV1 Vav guanine nucleotide exchange factor 1 VAV1 VAV1 protein (Vav guanine nucleotide exchange factor 1) Proto-oncogene vav |
Synonyms | VAV |
Description | FUNCTION: Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation. |
Accessions | P15498 L0R6S8 A0A2X0SZ57 ENST00000596764.5 [P15498-2] F5H5P4 Q96D37 ENST00000599806.5 ENST00000539284.2 ENST00000602142.6 [P15498-1] A0A0A0MR07 ENST00000304076.6 |