Interactors | Protein name | Directionality | Classification | |
|---|---|---|---|---|
| 1 | MICA-HCST+KLRK1 | MICA_HUMAN - | Ligand-Receptor | |
| 2 | RAET1E-HCST+KLRK1 | N2DL4_HUMAN - | Ligand-Receptor | Signaling by Killer Cell Lectin Like Receptor K1 |
| 3 | RAET1G-HCST+KLRK1 | RET1G_HUMAN - | Ligand-Receptor | Signaling by Killer Cell Lectin Like Receptor K1 |
| 4 | ULBP1-HCST+KLRK1 | N2DL1_HUMAN - | Ligand-Receptor | Signaling by Killer Cell Lectin Like Receptor K1 |
| 5 | ULBP2-HCST+KLRK1 | N2DL2_HUMAN - | Ligand-Receptor | Signaling by Killer Cell Lectin Like Receptor K1 |
| 6 | ULBP3-HCST+KLRK1 | N2DL3_HUMAN - | Ligand-Receptor | Signaling by Killer Cell Lectin Like Receptor K1 |
| Name | natural killer cell mediated cytotoxicity |
| ID | GO_0042267 |
| collection_id | Biological process |
| Exact synonym | NK cell mediated cell death, NK cell mediated cell killing, NK cell mediated cytotoxicity, natural killer cell mediated cell death, natural killer cell mediated cell killing |
| Description | The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. |
| Related synonym | NK cell mediated cytolysis, killer activity, natural killer cell mediated cytolysis, natural killer-cell mediated cytolysis |
| Comment | Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in induction of apoptosis in the target cell. |
| External URL | |
| Genes |