ULBP2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ULBP2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ULBP2 at tissue level.

III. Associated gene sets

GO_0006955Biological processimmune response
GO_0030101Biological processnatural killer cell activation
GO_0002476Biological processantigen processing and presentation of endogenous peptide antigen via MHC class Ib
GO_0002486Biological processantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
GO_0001916Biological processpositive regulation of T cell mediated cytotoxicity
GO_0042267Biological processnatural killer cell mediated cytotoxicity
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0005615Cellular componentextracellular space
GO_0009986Cellular componentcell surface
GO_0009897Cellular componentexternal side of plasma membrane
GO_0005783Cellular componentendoplasmic reticulum
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0046703Molecular functionnatural killer cell lectin-like receptor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameULBP2
Protein nameUL16-binding protein 2 (ALCAN-alpha) (NKG2D ligand 2) (N2DL-2) (NKG2DL2) (Retinoic acid early transcript 1H)
SynonymsRAET1H
UNQ463/PRO791
N2DL2
DescriptionFUNCTION: Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity. .

AccessionsQ9BZM5
ENST00000367351.4