I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| natural killer cell | 6 studies | 22% ± 2% | |
| CD16-positive, CD56-dim natural killer cell, human | 6 studies | 25% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| natural killer cell | 6 studies | 22% ± 2% | |
| CD16-positive, CD56-dim natural killer cell, human | 6 studies | 25% ± 5% |
Insufficient scRNA-seq data for expression of KIR3DL1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| spleen | 100% | 129.85 | 241 / 241 | 0% | 0 | 0 / 0 |
| lung | 96% | 53.59 | 554 / 578 | 4% | 0.10 | 44 / 1155 |
| peripheral blood | 80% | 450.40 | 747 / 929 | 0% | 0 | 0 / 0 |
| adipose | 59% | 9.64 | 713 / 1204 | 0% | 0 | 0 / 0 |
| liver | 48% | 6.38 | 108 / 226 | 0% | 0.01 | 2 / 406 |
| thymus | 45% | 5.36 | 294 / 653 | 1% | 0.01 | 5 / 605 |
| breast | 41% | 6.22 | 189 / 459 | 3% | 0.05 | 28 / 1118 |
| kidney | 18% | 1.82 | 16 / 89 | 10% | 0.17 | 87 / 901 |
| uterus | 19% | 2.18 | 33 / 170 | 4% | 0.28 | 19 / 459 |
| heart | 23% | 2.45 | 195 / 861 | 0% | 0 | 0 / 0 |
| intestine | 15% | 1.61 | 147 / 966 | 2% | 0.05 | 13 / 527 |
| bladder | 14% | 1.52 | 3 / 21 | 3% | 0.11 | 16 / 504 |
| prostate | 17% | 1.51 | 41 / 245 | 0% | 0 | 0 / 502 |
| blood vessel | 15% | 1.59 | 195 / 1335 | 0% | 0 | 0 / 0 |
| stomach | 10% | 0.96 | 36 / 359 | 5% | 0.08 | 13 / 286 |
| muscle | 13% | 1.02 | 105 / 803 | 0% | 0 | 0 / 0 |
| ovary | 12% | 1.37 | 21 / 180 | 1% | 0.02 | 6 / 430 |
| esophagus | 10% | 0.84 | 142 / 1445 | 3% | 0.04 | 5 / 183 |
| adrenal gland | 9% | 0.77 | 22 / 258 | 0% | 0 | 0 / 230 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 0.28 | 2 / 29 |
| brain | 7% | 0.56 | 177 / 2642 | 0% | 0 | 0 / 705 |
| tonsil | 0% | 0 | 0 / 0 | 7% | 0.14 | 3 / 45 |
| skin | 4% | 0.31 | 66 / 1809 | 3% | 0.04 | 12 / 472 |
| pancreas | 1% | 0.08 | 4 / 328 | 1% | 0.02 | 1 / 178 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006955 | Biological process | immune response |
| GO_0002764 | Biological process | immune response-regulating signaling pathway |
| GO_0042267 | Biological process | natural killer cell mediated cytotoxicity |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0001540 | Molecular function | amyloid-beta binding |
| GO_0030109 | Molecular function | HLA-B specific inhibitory MHC class I receptor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0060090 | Molecular function | molecular adaptor activity |
| Gene name | KIR3DL1 |
| Protein name | Killer cell immunoglobulin-like receptor 3DL1 (CD158 antigen-like family member E) (HLA-BW4-specific inhibitory NK cell receptor) (Natural killer-associated transcript 3) (NKAT-3) (p70 natural killer cell receptor clones CL-2/CL-11) (p70 NK receptor CL-2/CL-11) (CD antigen CD158e) KIR3DL1 (Killer cell immunoglobulin-like receptor 3DL1) (Killer cell immunoglobulin-like receptor three domains long cytoplasmic tail 1) (Natural killer cell inhibitory receptor) KIR3DL1 (Natural killer cell inhibitory receptor) KIR3DL1 (Killer cell immunoglobulin-like receptor) (Killer cell immunoglobulin-like receptor three domains long cytoplasmic tail 1) KIR3DL1 (Killer cell immunoglobulin-like receptor) (Killer cell immunoglobulin-like receptor three domains long cytoplasmic tail 1) (Natural killer cell inhibitory receptor) KIR3DL1 (Killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1) KIR3DL1 (Killer cell immunoglobulin-like receptor 3DL1) (Killer cell immunoglobulin-like receptor three domains long cytoplasmic tail 1) (Killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1) KIR3DL1 (Killer cell immunoglobulin-like receptor 3DL1) (Natural killer cell inhibitory receptor) KIR antigen 3DL1 KIR3DL1 (Killer cell immunoglobulin-like receptor 3DL1) KIR3DL1 KIR3DL1 (Killer cell immunoglobulin-like receptor) Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 (Killer cell immunoglobulin-like receptor 3DL1) Killer cell immunoglobulin-like receptor 3DL1/3DL2V KIR3DL1 protein KIR3DL1 (KIR3DL1/S1) (Killer cell immunoglobulin-like receptor) (Natural killer cell inhibitory receptor) KIR3DL1 (Killer cell immunoglobulin-like receptor) (Natural killer cell inhibitory receptor) Killer cell Ig-like receptor variant (Killer cell immunoglobulin-like receptor 3DL1) Killer cell immunoglobulin-like receptor 3DL1 (Killer cell immunoglobulin-like receptor three domains long cytoplasmic tail 1) Killer cell immunoglobulin receptor KIR3DL1 (KIR3DL1/S1) (Killer cell immunoglobulin-like receptor) Natural killer cell inhibitory receptor Killer cell immunoglobulin-like receptor 3DL1 |
| Synonyms | DL2V NKAT3 KIR3DL13DL1*009_extension_1 CD158E NKB1 KIR3DL13DL1*009_extension_2 KIR3DL13DL1*009_extension_4 KIR3DL13DL1*00402_extension_1 KIR3DL13DL1*019_extension_1 KIR3DL13DL1*009_extension_3 |
| Description | FUNCTION: Receptor on natural killer (NK) cells for HLA Bw4 allele. Inhibits the activity of NK cells thus preventing cell lysis. . |
| Accessions | ENST00000640472.1 ENST00000612571.1 ENST00000620450.2 I6LFJ9 A0A0G2JP89 A0A1D0BZT6 ENST00000610602.4 C4N363 E0X076 ENST00000640508.1 Q6H2G0 Q8N152 Q8NHK7 C4N364 Q8NHK9 B7S714 A0A5J6VN80 A0A1W2PRK8 Q1PSF1 E0X082 ENST00000639019.1 A0A1D0BRL8 Q5UCD8 A0A2I2JL13 ENST00000619211.4 ENST00000619931.4 ENST00000619271.1 ENST00000639170.1 A0A0G2JNM4 A0A376A8S6 C4N359 ENST00000358178.4 [P43629-2] Q8NHK8 A0A1W2PPM9 I6LEL6 ENST00000638344.1 A0A0G2JMK7 ENST00000614464.4 ENST00000640746.1 I6LFJ6 ENST00000611574.4 A0A2R4FYK3 E0X071 ENST00000639462.1 Q5UCD9 ENST00000640581.1 A0A0C4ZLQ8 I6LEK6 A0A1W2PS07 A0A1D0C0E9 C4N365 ENST00000612415.4 ENST00000639263.1 ENST00000638307.1 Q6H2G1 ENST00000621718.4 ENST00000638756.1 Q8N0X6 ENST00000326542.11 ENST00000640111.2 [P43629-2] A0A5J6VMJ0 ENST00000622691.3 ENST00000638528.1 ENST00000617680.4 ENST00000612668.4 [P43629-1] A0A2I2JL19 A0A0G2JPC2 B7S713 Q6H2G2 C4N361 A0A2R4FYK7 ENST00000620568.4 ENST00000640512.2 I6LEK9 A0A0C4ZN31 ENST00000613229.4 ENST00000620703.2 A0A0G2JNU1 ENST00000638533.1 ENST00000619476.4 ENST00000639012.1 A0A0G2JNF3 I6LFJ5 ENST00000639813.1 [P43629-2] ENST00000616188.4 [P43629-1] A0A1W2PP93 A0A1W2PQC9 E0X081 I6LEL9 ENST00000621759.2 ENST00000616424.1 A0A0G2JLX2 W5QJC1 ENST00000620959.4 A8QIT6 Q15702 ENST00000640399.1 Q6QWD6 I6LEL5 A0A2I2JL12 ENST00000391728.8 [P43629-1] A0A1W2PQG9 Q8NHL0 A0A0G2JQ40 ENST00000640788.1 [P43629-1] ENST00000638201.1 ENST00000640606.1 E0X079 ENST00000640659.1 ENST00000611451.4 A0A1D0BNM2 Q646T8 ENST00000620062.4 ENST00000639522.1 C4N362 ENST00000612933.4 ENST00000610515.3 ENST00000611230.4 ENST00000638564.1 E0X083 ENST00000622515.4 A0A1W2PNX4 ENST00000613869.4 A0A0G2JN48 A0A172R164 ENST00000615036.2 ENST00000638610.1 Q5UCE1 A0A0G2JPH7 ENST00000610345.4 A0A376A8V8 ENST00000614221.1 I6LEL4 E0X074 A0A2R4FYL2 A0A1D0C0D6 I6LFK0 Q8N6C9 A0A1D0BPY0 A0A0G2JN47 I6LEK8 A0A0G2JM22 A0A376A8U7 A0A5J6VNK5 C4N360 ENST00000621071.4 Q8N0Z7 A8DR97 P43629 A0A0G2JPV6 E0X084 ENST00000621353.4 [P43629-1] ENST00000611567.3 I6LEL0 A5X6C7 ENST00000619277.4 ENST00000615523.4 ENST00000640855.1 Q5UCE2 A0A2I2JL21 A0A5J6VQJ1 E0X078 ENST00000620834.4 A0A1D0BRL6 Q6H2G3 ENST00000614720.4 A0A5J6VN39 A6XI96 ENST00000639353.2 [P43629-1] A0A0G2JM66 A0A1W2PPW5 E0X073 I6LEM1 |
