TUBB4B | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	33 studies	41% ± 16%	Explore
fibroblast	31 studies	41% ± 18%	Explore
natural killer cell	29 studies	33% ± 13%	Explore
B cell	27 studies	30% ± 13%	Explore
pericyte	27 studies	43% ± 19%	Explore
macrophage	25 studies	33% ± 13%	Explore
smooth muscle cell	24 studies	43% ± 16%	Explore
CD8-positive, alpha-beta T cell	24 studies	35% ± 18%	Explore
T cell	23 studies	37% ± 16%	Explore
conventional dendritic cell	21 studies	35% ± 16%	Explore
basal cell	21 studies	55% ± 17%	Explore
epithelial cell	21 studies	57% ± 19%	Explore
ciliated cell	20 studies	81% ± 22%	Explore
regulatory T cell	20 studies	31% ± 14%	Explore
classical monocyte	19 studies	32% ± 13%	Explore
CD4-positive, alpha-beta T cell	19 studies	38% ± 20%	Explore
endothelial cell of lymphatic vessel	17 studies	50% ± 16%	Explore
non-classical monocyte	17 studies	36% ± 16%	Explore
mast cell	16 studies	29% ± 11%	Explore
monocyte	15 studies	26% ± 12%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	26% ± 9%	Explore
connective tissue cell	15 studies	40% ± 12%	Explore
dendritic cell	14 studies	35% ± 15%	Explore
gamma-delta T cell	14 studies	33% ± 13%	Explore
myofibroblast cell	13 studies	38% ± 17%	Explore
memory B cell	13 studies	30% ± 12%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	28% ± 11%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	30% ± 14%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	32% ± 11%	Explore
secretory cell	11 studies	46% ± 15%	Explore
mature NK T cell	11 studies	31% ± 11%	Explore
abnormal cell	11 studies	37% ± 15%	Explore
endothelial cell of vascular tree	11 studies	49% ± 18%	Explore
myeloid cell	11 studies	42% ± 16%	Explore
plasma cell	11 studies	39% ± 16%	Explore
capillary endothelial cell	10 studies	35% ± 12%	Explore
endothelial cell of artery	10 studies	37% ± 12%	Explore
vein endothelial cell	10 studies	38% ± 14%	Explore
type I pneumocyte	9 studies	52% ± 18%	Explore
type II pneumocyte	9 studies	43% ± 18%	Explore
goblet cell	9 studies	47% ± 15%	Explore
retinal rod cell	9 studies	57% ± 20%	Explore
plasmacytoid dendritic cell	9 studies	31% ± 12%	Explore
plasmablast	8 studies	49% ± 22%	Explore
leukocyte	8 studies	36% ± 12%	Explore
platelet	8 studies	35% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	31% ± 10%	Explore
progenitor cell	8 studies	41% ± 8%	Explore
neuron	8 studies	31% ± 10%	Explore
mesothelial cell	8 studies	38% ± 20%	Explore
mucosal invariant T cell	8 studies	29% ± 10%	Explore
club cell	7 studies	42% ± 19%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	42% ± 15%	Explore
naive B cell	7 studies	27% ± 7%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	7 studies	24% ± 9%	Explore
epithelial cell of proximal tubule	7 studies	39% ± 16%	Explore
transit amplifying cell	7 studies	48% ± 23%	Explore
retinal cone cell	7 studies	59% ± 26%	Explore
precursor B cell	7 studies	43% ± 19%	Explore
innate lymphoid cell	7 studies	36% ± 12%	Explore
erythrocyte	7 studies	46% ± 24%	Explore
alveolar macrophage	6 studies	21% ± 5%	Explore
ionocyte	6 studies	43% ± 8%	Explore
respiratory goblet cell	6 studies	39% ± 19%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	40% ± 9%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	22% ± 3%	Explore
renal alpha-intercalated cell	6 studies	43% ± 4%	Explore
enterocyte	6 studies	51% ± 6%	Explore
erythroblast	6 studies	51% ± 23%	Explore
retinal ganglion cell	6 studies	68% ± 25%	Explore
hematopoietic stem cell	6 studies	33% ± 10%	Explore
hematopoietic precursor cell	5 studies	40% ± 14%	Explore
kidney loop of Henle epithelial cell	5 studies	29% ± 8%	Explore
pro-B cell	5 studies	37% ± 7%	Explore
T follicular helper cell	5 studies	28% ± 10%	Explore
glutamatergic neuron	5 studies	32% ± 15%	Explore
deuterosomal cell	4 studies	74% ± 13%	Explore
squamous epithelial cell	4 studies	52% ± 19%	Explore
pancreatic A cell	4 studies	44% ± 21%	Explore
mononuclear phagocyte	4 studies	28% ± 15%	Explore
exhausted T cell	4 studies	24% ± 7%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	38% ± 9%	Explore
enteroendocrine cell	4 studies	46% ± 4%	Explore
amacrine cell	4 studies	34% ± 13%	Explore
retinal bipolar neuron	4 studies	58% ± 22%	Explore
OFF-bipolar cell	4 studies	58% ± 18%	Explore
ON-bipolar cell	4 studies	52% ± 19%	Explore
brush cell	4 studies	35% ± 18%	Explore
immature B cell	4 studies	27% ± 11%	Explore
astrocyte	4 studies	36% ± 14%	Explore
retina horizontal cell	4 studies	44% ± 14%	Explore
adventitial cell	4 studies	40% ± 15%	Explore
mucus secreting cell	4 studies	23% ± 1%	Explore
Mueller cell	4 studies	39% ± 9%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	50% ± 17%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	61% ± 9%	Explore
GABAergic neuron	4 studies	28% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	20% ± 1%	Explore
CD4-positive, alpha-beta cytotoxic T cell	4 studies	28% ± 16%	Explore
duct epithelial cell	3 studies	40% ± 1%	Explore
precursor cell	3 studies	44% ± 18%	Explore
type B pancreatic cell	3 studies	37% ± 21%	Explore
monocyte-derived dendritic cell	3 studies	47% ± 24%	Explore
glomerular endothelial cell	3 studies	34% ± 14%	Explore
intestinal crypt stem cell	3 studies	46% ± 8%	Explore
neural crest cell	3 studies	39% ± 15%	Explore
renal principal cell	3 studies	46% ± 7%	Explore
extravillous trophoblast	3 studies	60% ± 7%	Explore
placental villous trophoblast	3 studies	58% ± 5%	Explore
lymphocyte	3 studies	60% ± 5%	Explore
megakaryocyte	3 studies	39% ± 21%	Explore
neuroendocrine cell	3 studies	45% ± 17%	Explore
retinal pigment epithelial cell	3 studies	65% ± 22%	Explore
microglial cell	3 studies	46% ± 17%	Explore
intraepithelial lymphocyte	3 studies	28% ± 9%	Explore
rod bipolar cell	3 studies	51% ± 11%	Explore
intermediate monocyte	3 studies	43% ± 11%	Explore
CD4-positive helper T cell	3 studies	39% ± 15%	Explore
granulocyte	3 studies	42% ± 22%	Explore
luminal cell of prostate epithelium	3 studies	35% ± 3%	Explore
pancreatic ductal cell	3 studies	71% ± 9%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	50% ± 18%	Explore
glial cell	3 studies	25% ± 7%	Explore
group 3 innate lymphoid cell	3 studies	39% ± 14%	Explore
T-helper 1 cell	3 studies	42% ± 8%	Explore
double negative thymocyte	3 studies	34% ± 16%	Explore
progenitor cell of mammary luminal epithelium	3 studies	65% ± 7%	Explore
hepatocyte	3 studies	27% ± 10%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	17 studies	39% ± 11%	Explore
intestine	12 studies	34% ± 13%	Explore
peripheral blood	11 studies	32% ± 11%	Explore
eye	10 studies	51% ± 20%	Explore
kidney	8 studies	31% ± 8%	Explore
brain	6 studies	25% ± 9%	Explore
uterus	6 studies	49% ± 20%	Explore
liver	6 studies	35% ± 19%	Explore
lymph node	6 studies	31% ± 17%	Explore
bone marrow	5 studies	26% ± 8%	Explore
pancreas	4 studies	44% ± 17%	Explore
prostate	4 studies	55% ± 19%	Explore
breast	4 studies	57% ± 9%	Explore
placenta	3 studies	50% ± 10%	Explore
ovary	3 studies	35% ± 6%	Explore
esophagus	3 studies	43% ± 13%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	15157.73	1442 / 1445	100%	576.53	183 / 183
intestine	100%	11387.44	964 / 966	100%	776.42	525 / 527
prostate	100%	8167.16	244 / 245	99%	697.61	499 / 502
bladder	100%	7601.00	21 / 21	99%	703.58	498 / 504
skin	100%	18275.52	1808 / 1809	98%	374.59	464 / 472
stomach	99%	9081.87	354 / 359	99%	636.09	284 / 286
brain	98%	8816.82	2584 / 2642	100%	309.15	703 / 705
lung	98%	10203.42	565 / 578	99%	514.82	1140 / 1155
thymus	97%	8786.15	633 / 653	100%	498.90	602 / 605
kidney	100%	7838.63	89 / 89	95%	298.96	858 / 901
breast	94%	6685.47	432 / 459	98%	477.99	1096 / 1118
uterus	92%	6727.29	157 / 170	99%	790.44	456 / 459
adrenal gland	100%	7336.79	258 / 258	91%	250.88	210 / 230
pancreas	88%	3744.00	287 / 328	98%	408.24	175 / 178
ovary	82%	4671.74	147 / 180	100%	518.68	430 / 430
liver	88%	5158.69	199 / 226	92%	233.95	372 / 406
lymph node	0%	0	0 / 0	100%	547.09	29 / 29
tonsil	0%	0	0 / 0	100%	880.22	45 / 45
ureter	0%	0	0 / 0	100%	1153.75	1 / 1
eye	0%	0	0 / 0	99%	330.09	79 / 80
spleen	98%	6197.86	236 / 241	0%	0	0 / 0
heart	98%	16075.22	841 / 861	0%	0	0 / 0
muscle	97%	8078.21	779 / 803	0%	0	0 / 0
adipose	96%	7649.97	1158 / 1204	0%	0	0 / 0
blood vessel	95%	6528.91	1270 / 1335	0%	0	0 / 0
peripheral blood	92%	6654.39	856 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0000278	Biological process	mitotic cell cycle
GO_0042267	Biological process	natural killer cell mediated cytotoxicity
GO_0000226	Biological process	microtubule cytoskeleton organization
GO_0035578	Cellular component	azurophil granule lumen
GO_0005856	Cellular component	cytoskeleton
GO_0005576	Cellular component	extracellular region
GO_0005874	Cellular component	microtubule
GO_0072686	Cellular component	mitotic spindle
GO_0070062	Cellular component	extracellular exosome
GO_1903561	Cellular component	extracellular vesicle
GO_0045171	Cellular component	intercellular bridge
GO_0005879	Cellular component	axonemal microtubule
GO_0005829	Cellular component	cytosol
GO_0015630	Cellular component	microtubule cytoskeleton
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0005200	Molecular function	structural constituent of cytoskeleton
GO_0051082	Molecular function	unfolded protein binding
GO_0005525	Molecular function	GTP binding
GO_0042288	Molecular function	MHC class I protein binding
GO_0046872	Molecular function	metal ion binding
GO_0005515	Molecular function	protein binding
GO_0003725	Molecular function	double-stranded RNA binding
GO_0003924	Molecular function	GTPase activity

Gene name	TUBB4B
Protein name	Tubulin beta-4B chain (Tubulin beta-2 chain) (Tubulin beta-2C chain)
Synonyms	TUBB2C
Description	FUNCTION: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
Accessions	ENST00000340384.5 P68371

TUBB4B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review