ULBP3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ULBP3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ULBP3 at tissue level.

III. Associated gene sets

GO_0006955Biological processimmune response
GO_0030101Biological processnatural killer cell activation
GO_0002476Biological processantigen processing and presentation of endogenous peptide antigen via MHC class Ib
GO_0002486Biological processantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
GO_0001916Biological processpositive regulation of T cell mediated cytotoxicity
GO_0042267Biological processnatural killer cell mediated cytotoxicity
GO_0005615Cellular componentextracellular space
GO_0009897Cellular componentexternal side of plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0046703Molecular functionnatural killer cell lectin-like receptor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameULBP3
Protein nameUL16-binding protein 3 (ALCAN-gamma) (NKG2D ligand 3) (N2DL-3) (NKG2DL3) (Retinoic acid early transcript 1N)
SynonymsRAET1N
N2DL3
DescriptionFUNCTION: Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity. .

AccessionsENST00000367339.7
ENST00000438272.2
Q9BZM4