RAET1E report

I. Expression across cell types

Insufficient scRNA-seq data for expression of RAET1E at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of RAET1E at tissue level.

III. Associated gene sets

GO_0006955Biological processimmune response
GO_0045954Biological processpositive regulation of natural killer cell mediated cytotoxicity
GO_0002476Biological processantigen processing and presentation of endogenous peptide antigen via MHC class Ib
GO_0002486Biological processantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
GO_0001916Biological processpositive regulation of T cell mediated cytotoxicity
GO_0042267Biological processnatural killer cell mediated cytotoxicity
GO_0005615Cellular componentextracellular space
GO_0009897Cellular componentexternal side of plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0005515Molecular functionprotein binding
GO_0046703Molecular functionnatural killer cell lectin-like receptor binding

IV. Literature review

[source]
Gene nameRAET1E
Protein nameRetinoic acid early transcript 1E
Retinoic acid early transcript 1E (Lymphocyte effector toxicity activation ligand) (NKG2D ligand 4) (N2DL-4) (NKG2DL4) (RAE-1-like transcript 4) (UL16-binding protein 4)
RAET1E
RAET1E (ULBP4)
NKG2D ligand (RAET1E)
RAET1E protein (Retinoic acid early transcript 1E)
SynonymsLETAL
ULBP4
N2DL4
RAET-1E
UNQ1867/PRO4303
DescriptionFUNCTION: Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity. .

AccessionsENST00000357183.9 [Q8TD07-1]
Q3T1D4
I2GUA3
Q3ZAR2
ENST00000532335.5 [Q8TD07-3]
A0A0G3VUT9
ENST00000529948.1 [Q8TD07-4]
I2GUA6
I2GUA5
A0A060ILJ5
A0A0G3VRR7
I2GUA2
A0A0G3VTM3
I2GUA4
A0A0G3VTN0
A0A0G3VTF2
A0A0G3VTF8
A0A0G3VSE5
I7EC85
ENST00000392270.3
Q8TD07
ENST00000367363.3 [Q8TD07-2]
A0A0G3VTF5
I7FHP4