ULBP1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ULBP1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ULBP1 at tissue level.

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0006955Biological processimmune response
GO_0030101Biological processnatural killer cell activation
GO_0002476Biological processantigen processing and presentation of endogenous peptide antigen via MHC class Ib
GO_0002486Biological processantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
GO_0001916Biological processpositive regulation of T cell mediated cytotoxicity
GO_0042267Biological processnatural killer cell mediated cytotoxicity
GO_0005615Cellular componentextracellular space
GO_0009897Cellular componentexternal side of plasma membrane
GO_0005783Cellular componentendoplasmic reticulum
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0046703Molecular functionnatural killer cell lectin-like receptor binding
GO_0005515Molecular functionprotein binding
GO_0048018Molecular functionreceptor ligand activity

IV. Literature review

[source]
Gene nameULBP1
Protein nameUL16-binding protein 1 (ALCAN-beta) (NKG2D ligand 1) (N2DL-1) (NKG2DL1) (Retinoic acid early transcript 1I)
SynonymsN2DL1
RAET1I
DescriptionFUNCTION: Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity. .

AccessionsQ9BZM6
ENST00000229708.4