BCAR1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell of lymphatic vessel	16 studies	27% ± 8%	Explore
endothelial cell	15 studies	25% ± 8%	Explore
pericyte	10 studies	25% ± 5%	Explore
epithelial cell	6 studies	25% ± 9%	Explore
oligodendrocyte	5 studies	22% ± 6%	Explore
capillary endothelial cell	4 studies	20% ± 1%	Explore
vein endothelial cell	4 studies	23% ± 5%	Explore
endothelial cell of vascular tree	4 studies	20% ± 5%	Explore
pancreatic A cell	3 studies	19% ± 4%	Explore
neuron	3 studies	26% ± 8%	Explore
endothelial cell of artery	3 studies	17% ± 2%	Explore
ciliated cell	3 studies	17% ± 1%	Explore
oligodendrocyte precursor cell	3 studies	30% ± 8%	Explore
goblet cell	3 studies	19% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
pancreas	3 studies	18% ± 2%	Explore
lung	3 studies	18% ± 2%	Explore
brain	3 studies	32% ± 2%	Explore
intestine	3 studies	19% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
pancreas	100%	4074.98	328 / 328	100%	50.77	178 / 178
kidney	100%	8397.66	89 / 89	100%	44.22	898 / 901
esophagus	100%	3695.48	1445 / 1445	99%	42.57	182 / 183
intestine	100%	5044.06	966 / 966	99%	39.75	524 / 527
uterus	100%	5906.88	170 / 170	99%	36.88	456 / 459
stomach	100%	5766.51	359 / 359	99%	38.80	284 / 286
prostate	100%	5409.27	245 / 245	99%	23.48	498 / 502
adrenal gland	100%	4240.26	258 / 258	99%	34.04	228 / 230
brain	99%	4755.39	2616 / 2642	100%	42.86	703 / 705
lung	100%	6380.59	577 / 578	99%	31.22	1140 / 1155
bladder	100%	4246.81	21 / 21	98%	34.37	496 / 504
ovary	100%	3351.73	180 / 180	98%	22.23	422 / 430
thymus	100%	5335.31	653 / 653	98%	27.33	591 / 605
skin	99%	4126.90	1788 / 1809	99%	37.05	465 / 472
breast	100%	4793.12	459 / 459	97%	23.64	1088 / 1118
liver	100%	3945.79	226 / 226	96%	21.01	391 / 406
muscle	100%	8007.26	803 / 803	0%	0	0 / 0
spleen	100%	7220.63	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	26.86	45 / 45
ureter	0%	0	0 / 0	100%	54.57	1 / 1
adipose	100%	5313.68	1203 / 1204	0%	0	0 / 0
blood vessel	100%	8237.79	1333 / 1335	0%	0	0 / 0
heart	99%	5182.32	854 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	98%	21.52	78 / 80
lymph node	0%	0	0 / 0	41%	4.24	12 / 29
peripheral blood	13%	271.04	118 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0050851	Biological process	antigen receptor-mediated signaling pathway
GO_0007169	Biological process	cell surface receptor protein tyrosine kinase signaling pathway
GO_0001558	Biological process	regulation of cell growth
GO_0048011	Biological process	neurotrophin TRK receptor signaling pathway
GO_0035729	Biological process	cellular response to hepatocyte growth factor stimulus
GO_0010595	Biological process	positive regulation of endothelial cell migration
GO_0050853	Biological process	B cell receptor signaling pathway
GO_0051301	Biological process	cell division
GO_0007155	Biological process	cell adhesion
GO_0050852	Biological process	T cell receptor signaling pathway
GO_0048008	Biological process	platelet-derived growth factor receptor signaling pathway
GO_0007186	Biological process	G protein-coupled receptor signaling pathway
GO_0008286	Biological process	insulin receptor signaling pathway
GO_0007229	Biological process	integrin-mediated signaling pathway
GO_0042981	Biological process	regulation of apoptotic process
GO_0030335	Biological process	positive regulation of cell migration
GO_0007015	Biological process	actin filament organization
GO_0007173	Biological process	epidermal growth factor receptor signaling pathway
GO_0048012	Biological process	hepatocyte growth factor receptor signaling pathway
GO_0048010	Biological process	vascular endothelial growth factor receptor signaling pathway
GO_0086100	Biological process	endothelin receptor signaling pathway
GO_0016477	Biological process	cell migration
GO_0060326	Biological process	cell chemotaxis
GO_0001726	Cellular component	ruffle
GO_0005886	Cellular component	plasma membrane
GO_0005925	Cellular component	focal adhesion
GO_0015629	Cellular component	actin cytoskeleton
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0030424	Cellular component	axon
GO_0030027	Cellular component	lamellipodium
GO_0019901	Molecular function	protein kinase binding
GO_0005515	Molecular function	protein binding
GO_0017124	Molecular function	SH3 domain binding

IV. Literature review

[source]

Gene name	BCAR1
Protein name	Breast cancer anti-estrogen resistance 1, isoform CRA_b (cDNA FLJ42535 fis, clone BRACE3003595, highly similar to Breast cancer anti-estrogen resistance protein 1) Breast cancer anti-estrogen resistance 1 Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas) BCAR1 scaffold protein, Cas family member
Synonyms	CAS hCG_20581 CASS1 CRKAS
Description	FUNCTION: Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion . Implicated in induction of cell migration and cell branching . Involved in the BCAR3-mediated inhibition of TGFB signaling (By similarity). .
Accessions	ENST00000393420.10 [P56945-3] H3BN62 H3BSB2 Q6P5Z4 H3BU42 ENST00000542031.6 [P56945-5] ENST00000538440.6 [P56945-8] ENST00000563323.1 H3BVF0 ENST00000567215.1 P56945 B3KW85 ENST00000420641.7 [P56945-2] ENST00000162330.10 [P56945-1] F5H855 H3BSY4 H3BTB0 ENST00000546196.2 ENST00000564028.1 ENST00000568864.1 ENST00000569006.1 H3BTL5 ENST00000418647.7 [P56945-6] ENST00000561970.1 ENST00000569340.1 ENST00000566465.1 ENST00000393422.6 [P56945-7] ENST00000562556.5 ENST00000535626.6 [P56945-4] H3BQJ7

BCAR1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review