GO_0007169 | OmnibusX

	Interactors	Protein name	Directionality	Classification
1	BDNF-NTRK2	BDNF_HUMAN - NTRK2_HUMAN	Ligand-Receptor	Signaling by Brain-derived neurotrophic factor
2	CSF1-CSF1R	CSF1_HUMAN - CSF1R_HUMAN	Ligand-Receptor	Signaling by Colony-Stimulating factor
3	LCK-CD8A+CD8B	LCK_HUMAN -	Receptor-Receptor
4	NGF-NTRK1	NGF_HUMAN - NTRK1_HUMAN	Ligand-Receptor	Signaling by Beta-nerve growth factor
5	NRTN-GFRA2+RET	NRTN_HUMAN -	Ligand-Receptor	Signaling by Neurotrophin
6	NTF3-NTRK1	NTF3_HUMAN - NTRK1_HUMAN	Ligand-Receptor	Signaling by Neurotrophin
7	NTF3-NTRK2	NTF3_HUMAN - NTRK2_HUMAN	Ligand-Receptor	Signaling by Neurotrophin
8	NTF3-NTRK3	NTF3_HUMAN - NTRK3_HUMAN	Ligand-Receptor	Signaling by Neurotrophin
9	NTF4-NTRK2	NTF4_HUMAN - NTRK2_HUMAN	Ligand-Receptor	Signaling by Neurotrophin

Name	cell surface receptor protein tyrosine kinase signaling pathway
ID	GO_0007169
collection_id	Biological process
Exact synonym	transmembrane receptor protein tyrosine kinase signalling pathway
Description	The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.
External URL
Genes	AHI1 CNKSR1 ERBB2 DDR1 ROS1 FYN CSF1R AXL CD8B RET PDGFRA NGF NTRK3 ABI1 TRADD HCK MET FGFR1 TYRO3 NTRK2 BDKRB2 NTRK1 SYK ROR2 LCK PTK6 TIE1 CD4 MTSS1 RYK ERBB3 PTPRT ALKAL1 MERTK IL31RA EGFR FGR NTF4 INSRR POLR1G TRAT1 FRK ERBB4 FGFR4 CD3E KDR DOK5 LCP2 INSR DOK4 SH2B3 PTPRG MUSK NEDD9 ALKAL2 SHC4 SAMD10 DOK1 BLNK FLT4 FLT1 BCAR1 BDNF EPHA2 CSF1 LYN FLT3 ALK YES1 SRMS BLK ZAP70 CASS4 GFRA2 PDGFRB RAPGEF1 DOK2 ANGPTL1 CD8A SHC2 SAMD12 MPZL1 DDR2 SH2B1 DOK3 FGFR3 CLNK SH2D6 PILRB CD7 EFS NRTN DOK6 PIK3CB STAP1 GAB2 ROR1 SHC3 GAB4 TEK NTF3 FGFR2 MST1R LTK

cell surface receptor protein tyrosine kinase signaling pathway