NRTN report

I. Expression across cell types

Insufficient scRNA-seq data for expression of NRTN at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of NRTN at tissue level.

III. Associated gene sets

GO_0021675Biological processnerve development
GO_0007399Biological processnervous system development
GO_0035860Biological processglial cell-derived neurotrophic factor receptor signaling pathway
GO_0007169Biological processcell surface receptor protein tyrosine kinase signaling pathway
GO_0001755Biological processneural crest cell migration
GO_0000165Biological processMAPK cascade
GO_0031175Biological processneuron projection development
GO_0005615Cellular componentextracellular space
GO_0030424Cellular componentaxon
GO_0005576Cellular componentextracellular region
GO_0030116Molecular functionglial cell-derived neurotrophic factor receptor binding
GO_1904399Molecular functionheparan sulfate binding
GO_0005102Molecular functionsignaling receptor binding
GO_0030971Molecular functionreceptor tyrosine kinase binding
GO_0008083Molecular functiongrowth factor activity

IV. Literature review

[source]
Gene nameNRTN
Protein nameNeurturin
Synonyms
DescriptionFUNCTION: Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells.

AccessionsQ99748
ENST00000303212.3