SHC4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006915Biological processapoptotic process
GO_0008284Biological processpositive regulation of cell population proliferation
GO_0010468Biological processregulation of gene expression
GO_0035556Biological processintracellular signal transduction
GO_0048863Biological processstem cell differentiation
GO_0007169Biological processcell surface receptor protein tyrosine kinase signaling pathway
GO_0005886Cellular componentplasma membrane
GO_0045211Cellular componentpostsynaptic membrane
GO_0019904Molecular functionprotein domain specific binding
GO_0005515Molecular functionprotein binding
GO_0030971Molecular functionreceptor tyrosine kinase binding

IV. Literature review

[source]
Gene nameSHC4
Protein nameSHC adaptor protein 4
SHC-transforming protein 4 (Rai-like protein) (RaLP) (SHC-transforming protein D) (hShcD) (Src homology 2 domain-containing-transforming protein C4) (SH2 domain protein C4)
SynonymsUNQ6438/PRO21364
SHCD
DescriptionFUNCTION: Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1. .

AccessionsENST00000537958.5
ENST00000557797.5
H0YLZ2
ENST00000558220.1
H0YLU6
F5H5M1
ENST00000332408.9 [Q6S5L8-1]
ENST00000396535.7 [Q6S5L8-2]
Q6S5L8