Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| B cell | 17 studies | 20% ± 3% | |
| naive B cell | 16 studies | 23% ± 5% | |
| memory B cell | 7 studies | 19% ± 3% | |
| ionocyte | 5 studies | 63% ± 20% | |
| mast cell | 5 studies | 27% ± 16% | |
| renal alpha-intercalated cell | 4 studies | 33% ± 7% | |
| germinal center B cell | 3 studies | 25% ± 5% |
Insufficient scRNA-seq data for expression of STAP1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 98% | 70.82 | 568 / 578 | 69% | 2.61 | 793 / 1155 |
| prostate | 88% | 46.20 | 215 / 245 | 55% | 5.05 | 275 / 502 |
| kidney | 100% | 489.29 | 89 / 89 | 34% | 29.34 | 303 / 901 |
| breast | 58% | 16.58 | 264 / 459 | 60% | 2.22 | 675 / 1118 |
| stomach | 84% | 39.09 | 301 / 359 | 30% | 1.83 | 87 / 286 |
| bladder | 81% | 36.10 | 17 / 21 | 28% | 1.80 | 142 / 504 |
| esophagus | 76% | 30.56 | 1098 / 1445 | 32% | 1.15 | 58 / 183 |
| intestine | 74% | 174.53 | 714 / 966 | 27% | 1.73 | 144 / 527 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 95.47 | 29 / 29 |
| spleen | 100% | 1178.42 | 241 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 99% | 763.03 | 921 / 929 | 0% | 0 | 0 / 0 |
| uterus | 59% | 14.09 | 100 / 170 | 36% | 0.88 | 164 / 459 |
| pancreas | 35% | 8.40 | 116 / 328 | 49% | 3.45 | 88 / 178 |
| adipose | 73% | 24.28 | 883 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 67% | 3.70 | 30 / 45 |
| skin | 28% | 6.49 | 513 / 1809 | 36% | 2.79 | 171 / 472 |
| thymus | 26% | 35.19 | 172 / 653 | 34% | 1.89 | 206 / 605 |
| liver | 31% | 5.95 | 71 / 226 | 8% | 0.56 | 33 / 406 |
| blood vessel | 29% | 12.55 | 386 / 1335 | 0% | 0 | 0 / 0 |
| ovary | 8% | 1.44 | 15 / 180 | 19% | 0.32 | 83 / 430 |
| brain | 6% | 3.59 | 156 / 2642 | 6% | 0.34 | 45 / 705 |
| adrenal gland | 5% | 0.84 | 13 / 258 | 4% | 0.08 | 9 / 230 |
| heart | 7% | 1.79 | 61 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 4% | 0.08 | 3 / 80 |
| muscle | 3% | 0.73 | 28 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_1903980 | Biological process | positive regulation of microglial cell activation |
| GO_0007169 | Biological process | cell surface receptor protein tyrosine kinase signaling pathway |
| GO_0010628 | Biological process | positive regulation of gene expression |
| GO_0050861 | Biological process | positive regulation of B cell receptor signaling pathway |
| GO_0042326 | Biological process | negative regulation of phosphorylation |
| GO_0010760 | Biological process | negative regulation of macrophage chemotaxis |
| GO_0071222 | Biological process | cellular response to lipopolysaccharide |
| GO_1902227 | Biological process | negative regulation of macrophage colony-stimulating factor signaling pathway |
| GO_1904140 | Biological process | negative regulation of microglial cell migration |
| GO_1900028 | Biological process | negative regulation of ruffle assembly |
| GO_0060100 | Biological process | positive regulation of phagocytosis, engulfment |
| GO_1904151 | Biological process | positive regulation of microglial cell mediated cytotoxicity |
| GO_0034451 | Cellular component | centriolar satellite |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0032991 | Cellular component | protein-containing complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0005157 | Molecular function | macrophage colony-stimulating factor receptor binding |
| GO_0005543 | Molecular function | phospholipid binding |
| GO_0019901 | Molecular function | protein kinase binding |
| GO_0005068 | Molecular function | transmembrane receptor protein tyrosine kinase adaptor activity |
| GO_0030296 | Molecular function | protein tyrosine kinase activator activity |
| GO_0035591 | Molecular function | signaling adaptor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0001784 | Molecular function | phosphotyrosine residue binding |
| Gene name | STAP1 |
| Protein name | Signal-transducing adaptor protein 1 (STAP-1) (BCR downstream-signaling protein 1) (Docking protein BRDG1) (Stem cell adaptor protein 1) |
| Synonyms | BRDG1 |
| Description | FUNCTION: In BCR signaling, appears to function as a docking protein acting downstream of TEC and participates in a positive feedback loop by increasing the activity of TEC. . |
| Accessions | ENST00000265404.7 Q9ULZ2 ENST00000396225.1 |
