SRMS report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SRMS at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SRMS at tissue level.

III. Associated gene sets

GO_0038083Biological processpeptidyl-tyrosine autophosphorylation
GO_0018108Biological processpeptidyl-tyrosine phosphorylation
GO_0006468Biological processprotein phosphorylation
GO_1904263Biological processpositive regulation of TORC1 signaling
GO_0030154Biological processcell differentiation
GO_0007169Biological processcell surface receptor protein tyrosine kinase signaling pathway
GO_0009968Biological processnegative regulation of signal transduction
GO_0045087Biological processinnate immune response
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0004713Molecular functionprotein tyrosine kinase activity
GO_0004715Molecular functionnon-membrane spanning protein tyrosine kinase activity
GO_0005524Molecular functionATP binding
GO_0005102Molecular functionsignaling receptor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSRMS
Protein nameTyrosine-protein kinase Srms (EC 2.7.10.2)
SynonymsC20orf148
DescriptionFUNCTION: Non-receptor tyrosine-protein kinase which phosphorylates DOK1 on tyrosine residues . Also phosphorylates KHDRBS1/SAM68 and VIM on tyrosine residues . Phosphorylation of KHDRBS1 is EGF-dependent . Phosphorylates OTUB1, promoting deubiquitination of RPTOR . .

AccessionsQ9H3Y6
ENST00000217188.2