I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| smooth muscle cell | 4 studies | 24% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| smooth muscle cell | 4 studies | 24% ± 4% |
Insufficient scRNA-seq data for expression of NTF3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 100% | 543.77 | 180 / 180 | 65% | 6.61 | 281 / 430 |
| prostate | 98% | 239.20 | 239 / 245 | 62% | 1.30 | 310 / 502 |
| kidney | 83% | 153.58 | 74 / 89 | 44% | 1.27 | 397 / 901 |
| uterus | 87% | 207.18 | 148 / 170 | 26% | 2.02 | 121 / 459 |
| bladder | 90% | 321.19 | 19 / 21 | 20% | 0.64 | 102 / 504 |
| liver | 95% | 237.78 | 215 / 226 | 16% | 0.33 | 63 / 406 |
| lung | 70% | 93.72 | 406 / 578 | 35% | 1.39 | 406 / 1155 |
| breast | 82% | 174.70 | 378 / 459 | 22% | 1.27 | 244 / 1118 |
| stomach | 75% | 121.68 | 269 / 359 | 28% | 0.75 | 80 / 286 |
| blood vessel | 100% | 1351.20 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| intestine | 75% | 98.11 | 725 / 966 | 21% | 0.43 | 109 / 527 |
| spleen | 95% | 200.02 | 228 / 241 | 0% | 0 | 0 / 0 |
| adipose | 83% | 219.35 | 996 / 1204 | 0% | 0 | 0 / 0 |
| skin | 66% | 113.42 | 1187 / 1809 | 11% | 0.47 | 51 / 472 |
| esophagus | 54% | 78.40 | 779 / 1445 | 18% | 0.63 | 33 / 183 |
| heart | 64% | 89.11 | 550 / 861 | 0% | 0 | 0 / 0 |
| thymus | 42% | 47.64 | 277 / 653 | 21% | 1.43 | 127 / 605 |
| adrenal gland | 16% | 17.13 | 42 / 258 | 25% | 0.72 | 57 / 230 |
| tonsil | 0% | 0 | 0 / 0 | 40% | 1.28 | 18 / 45 |
| muscle | 39% | 42.46 | 311 / 803 | 0% | 0 | 0 / 0 |
| pancreas | 1% | 0.69 | 3 / 328 | 30% | 0.49 | 54 / 178 |
| brain | 20% | 70.79 | 527 / 2642 | 2% | 0.13 | 13 / 705 |
| eye | 0% | 0 | 0 / 0 | 9% | 0.23 | 7 / 80 |
| peripheral blood | 0% | 0.07 | 1 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0032148 | Biological process | activation of protein kinase B activity |
| GO_0050804 | Biological process | modulation of chemical synaptic transmission |
| GO_0007169 | Biological process | cell surface receptor protein tyrosine kinase signaling pathway |
| GO_0021675 | Biological process | nerve development |
| GO_0090630 | Biological process | activation of GTPase activity |
| GO_0050918 | Biological process | positive chemotaxis |
| GO_0007165 | Biological process | signal transduction |
| GO_0033138 | Biological process | positive regulation of peptidyl-serine phosphorylation |
| GO_0038180 | Biological process | nerve growth factor signaling pathway |
| GO_0002092 | Biological process | positive regulation of receptor internalization |
| GO_0007267 | Biological process | cell-cell signaling |
| GO_0048812 | Biological process | neuron projection morphogenesis |
| GO_0050732 | Biological process | negative regulation of peptidyl-tyrosine phosphorylation |
| GO_0043406 | Biological process | positive regulation of MAP kinase activity |
| GO_0042981 | Biological process | regulation of apoptotic process |
| GO_0050731 | Biological process | positive regulation of peptidyl-tyrosine phosphorylation |
| GO_0030335 | Biological process | positive regulation of cell migration |
| GO_0008284 | Biological process | positive regulation of cell population proliferation |
| GO_0050930 | Biological process | induction of positive chemotaxis |
| GO_0043524 | Biological process | negative regulation of neuron apoptotic process |
| GO_0007399 | Biological process | nervous system development |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0030425 | Cellular component | dendrite |
| GO_0008021 | Cellular component | synaptic vesicle |
| GO_0030424 | Cellular component | axon |
| GO_0005163 | Molecular function | nerve growth factor receptor binding |
| GO_0005102 | Molecular function | signaling receptor binding |
| GO_0008083 | Molecular function | growth factor activity |
| GO_0042056 | Molecular function | chemoattractant activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | NTF3 |
| Protein name | Neurotrophin-3 (NT-3) (HDNF) (Nerve growth factor 2) (NGF-2) (Neurotrophic factor) |
| Synonyms | |
| Description | FUNCTION: Seems to promote the survival of visceral and proprioceptive sensory neurons. |
| Accessions | ENST00000331010.7 [P20783-1] ENST00000423158.4 [P20783-2] P20783 |
