Interactors | Protein name | Directionality | Classification | |
|---|---|---|---|---|
| 1 | BDNF-SORT1 | BDNF_HUMAN - SORT_HUMAN | Ligand-Receptor | Signaling by Brain-derived neurotrophic factor |
| 2 | NGF-NTRK1 | NGF_HUMAN - NTRK1_HUMAN | Ligand-Receptor | Signaling by Beta-nerve growth factor |
| 3 | NGF-SORT1 | NGF_HUMAN - SORT_HUMAN | Ligand-Receptor | Signaling by Beta-nerve growth factor |
| 4 | NTF3-NTRK1 | NTF3_HUMAN - NTRK1_HUMAN | Ligand-Receptor | Signaling by Neurotrophin |
| Name | nerve growth factor signaling pathway |
| ID | GO_0038180 |
| collection_id | Biological process |
| Exact synonym | NGF signaling pathway, nerve growth factor signalling pathway |
| Description | The series of molecular signals initiated by nerve growth factor (NGF) binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. |
| Comment | Nerve growth factor (NGF) binds at least two classes of receptors: the p75 LNGFR (low-affinity nerve growth factor receptor) and TrkA, a transmembrane tyrosine kinase. |
| External URL | |
| Genes |