Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 27 studies | 31% ± 14% | |
fibroblast | 23 studies | 24% ± 9% | |
astrocyte | 20 studies | 38% ± 18% | |
pericyte | 19 studies | 24% ± 12% | |
oligodendrocyte | 15 studies | 49% ± 18% | |
oligodendrocyte precursor cell | 14 studies | 42% ± 19% | |
mast cell | 13 studies | 25% ± 9% | |
smooth muscle cell | 13 studies | 24% ± 7% | |
glutamatergic neuron | 12 studies | 53% ± 22% | |
macrophage | 12 studies | 30% ± 14% | |
microglial cell | 12 studies | 33% ± 12% | |
GABAergic neuron | 11 studies | 54% ± 24% | |
neuron | 10 studies | 52% ± 19% | |
epithelial cell | 9 studies | 33% ± 12% | |
endothelial cell of lymphatic vessel | 8 studies | 25% ± 8% | |
type II pneumocyte | 8 studies | 32% ± 9% | |
amacrine cell | 8 studies | 33% ± 11% | |
adipocyte | 8 studies | 30% ± 7% | |
type I pneumocyte | 7 studies | 23% ± 6% | |
interneuron | 6 studies | 70% ± 17% | |
retinal ganglion cell | 6 studies | 48% ± 16% | |
myeloid cell | 6 studies | 26% ± 6% | |
basal cell | 6 studies | 27% ± 13% | |
club cell | 6 studies | 25% ± 8% | |
retina horizontal cell | 6 studies | 42% ± 16% | |
Mueller cell | 6 studies | 25% ± 10% | |
monocyte | 6 studies | 24% ± 6% | |
natural killer cell | 5 studies | 20% ± 3% | |
classical monocyte | 5 studies | 24% ± 9% | |
non-classical monocyte | 5 studies | 25% ± 9% | |
capillary endothelial cell | 5 studies | 20% ± 4% | |
myofibroblast cell | 5 studies | 22% ± 9% | |
cardiac muscle cell | 5 studies | 38% ± 10% | |
dendritic cell | 5 studies | 25% ± 10% | |
lymphocyte | 5 studies | 24% ± 8% | |
connective tissue cell | 5 studies | 23% ± 2% | |
CD16-positive, CD56-dim natural killer cell, human | 4 studies | 17% ± 1% | |
effector memory CD8-positive, alpha-beta T cell | 4 studies | 16% ± 0% | |
abnormal cell | 4 studies | 25% ± 11% | |
retinal bipolar neuron | 4 studies | 25% ± 4% | |
granule cell | 4 studies | 39% ± 8% | |
retinal cone cell | 4 studies | 26% ± 6% | |
ciliated cell | 4 studies | 23% ± 7% | |
endothelial cell of vascular tree | 4 studies | 26% ± 12% | |
goblet cell | 4 studies | 31% ± 18% | |
CD4-positive, alpha-beta T cell | 3 studies | 16% ± 0% | |
conventional dendritic cell | 3 studies | 27% ± 9% | |
glomerular endothelial cell | 3 studies | 22% ± 2% | |
GABAergic interneuron | 3 studies | 61% ± 9% | |
glial cell | 3 studies | 35% ± 7% | |
progenitor cell | 3 studies | 36% ± 4% | |
brush cell | 3 studies | 26% ± 10% | |
endothelial cell of artery | 3 studies | 17% ± 1% | |
GABAergic amacrine cell | 3 studies | 46% ± 13% | |
OFF-bipolar cell | 3 studies | 27% ± 3% | |
ON-bipolar cell | 3 studies | 31% ± 3% | |
glycinergic amacrine cell | 3 studies | 36% ± 10% | |
rod bipolar cell | 3 studies | 33% ± 9% | |
secretory cell | 3 studies | 18% ± 1% | |
CD8-positive, alpha-beta memory T cell | 3 studies | 16% ± 1% | |
hepatocyte | 3 studies | 30% ± 13% | |
CD8-positive, alpha-beta T cell | 3 studies | 19% ± 3% | |
ependymal cell | 3 studies | 38% ± 21% | |
enteroendocrine cell | 3 studies | 26% ± 8% | |
adventitial cell | 3 studies | 20% ± 4% | |
T cell | 3 studies | 21% ± 1% | |
alveolar macrophage | 3 studies | 27% ± 9% | |
renal alpha-intercalated cell | 3 studies | 19% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 6221.11 | 1445 / 1445 | 100% | 23.56 | 183 / 183 |
brain | 100% | 9448.20 | 2641 / 2642 | 100% | 46.58 | 702 / 705 |
lung | 100% | 6801.41 | 578 / 578 | 99% | 21.51 | 1145 / 1155 |
breast | 100% | 6466.60 | 459 / 459 | 99% | 24.81 | 1103 / 1118 |
stomach | 100% | 4649.74 | 359 / 359 | 98% | 15.82 | 281 / 286 |
intestine | 100% | 6954.31 | 966 / 966 | 98% | 13.81 | 517 / 527 |
prostate | 100% | 5194.80 | 245 / 245 | 98% | 20.70 | 491 / 502 |
thymus | 100% | 6639.64 | 653 / 653 | 98% | 23.76 | 591 / 605 |
ovary | 100% | 9907.77 | 180 / 180 | 98% | 13.98 | 420 / 430 |
bladder | 100% | 6974.81 | 21 / 21 | 97% | 15.82 | 489 / 504 |
kidney | 100% | 4134.96 | 89 / 89 | 97% | 19.93 | 873 / 901 |
skin | 100% | 5578.51 | 1806 / 1809 | 97% | 22.33 | 458 / 472 |
pancreas | 98% | 2901.24 | 323 / 328 | 98% | 16.93 | 174 / 178 |
adrenal gland | 100% | 6201.88 | 258 / 258 | 96% | 30.44 | 221 / 230 |
uterus | 100% | 9065.46 | 170 / 170 | 95% | 16.94 | 437 / 459 |
liver | 98% | 2244.09 | 221 / 226 | 77% | 7.46 | 311 / 406 |
adipose | 100% | 6786.19 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 8259.48 | 1335 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 5251.54 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 4205.42 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 4.76 | 1 / 1 |
eye | 0% | 0 | 0 / 0 | 98% | 18.92 | 78 / 80 |
heart | 97% | 4863.81 | 839 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 93% | 14.60 | 42 / 45 |
peripheral blood | 77% | 2429.44 | 719 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 66% | 7.55 | 19 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0038180 | Biological process | nerve growth factor signaling pathway |
GO_0001701 | Biological process | in utero embryonic development |
GO_0010976 | Biological process | positive regulation of neuron projection development |
GO_1990090 | Biological process | cellular response to nerve growth factor stimulus |
GO_0048813 | Biological process | dendrite morphogenesis |
GO_0032991 | Cellular component | protein-containing complex |
GO_0005829 | Cellular component | cytosol |
GO_0005770 | Cellular component | late endosome |
GO_0016020 | Cellular component | membrane |
GO_0030165 | Molecular function | PDZ domain binding |
GO_0019887 | Molecular function | protein kinase regulator activity |
Gene name | KIDINS220 |
Protein name | Kinase D interacting substrate 220 Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein) Truncated KIDINS220 isoform h2 Truncated KIDINS220 isoform h3 Kinase D-interacting substrate of 220 kDa Truncated KIDINS220 isoform h1 |
Synonyms | KIAA1250 ARMS |
Description | FUNCTION: Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway. . |
Accessions | ENST00000689369.1 A0A8I5KTL1 ENST00000687894.1 ENST00000687912.1 ENST00000473731.5 [Q9ULH0-4] ENST00000488729.5 ENST00000692419.1 A0A8I5KT58 ENST00000691030.1 A0A8I5QL22 ENST00000686906.1 Q9ULH0 A0A076N408 A0A8I5QJC0 ENST00000638224.1 ENST00000689531.1 A0A8I5KX08 A0A1W2PPY4 A0A1W2PPB7 ENST00000569008.2 A0A8I5KQK7 A0A076NBC8 ENST00000319688.5 [Q9ULH0-3] A0A8I5KPM9 G1UI41 ENST00000689852.1 F8WAY8 ENST00000496383.5 ENST00000459813.2 H0Y8E4 ENST00000489024.5 A0A076N8A7 E9PH70 ENST00000693432.1 ENST00000685097.1 [Q9ULH0-2] A0A8I5KTG3 ENST00000256707.8 [Q9ULH0-1] A0A8I5KZ42 H7C584 ENST00000693394.1 |