Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 20 studies | 47% ± 22% | |
astrocyte | 19 studies | 75% ± 21% | |
fibroblast | 16 studies | 49% ± 17% | |
oligodendrocyte | 15 studies | 92% ± 8% | |
oligodendrocyte precursor cell | 14 studies | 79% ± 17% | |
glutamatergic neuron | 12 studies | 88% ± 11% | |
smooth muscle cell | 12 studies | 47% ± 18% | |
GABAergic neuron | 11 studies | 82% ± 17% | |
pericyte | 11 studies | 37% ± 16% | |
microglial cell | 10 studies | 48% ± 22% | |
adipocyte | 10 studies | 66% ± 18% | |
mesothelial cell | 9 studies | 57% ± 16% | |
mast cell | 7 studies | 28% ± 8% | |
endothelial cell of lymphatic vessel | 7 studies | 31% ± 10% | |
neuron | 6 studies | 62% ± 19% | |
epithelial cell | 6 studies | 37% ± 22% | |
interneuron | 6 studies | 84% ± 15% | |
amacrine cell | 6 studies | 71% ± 37% | |
retina horizontal cell | 6 studies | 74% ± 34% | |
cardiac muscle cell | 6 studies | 53% ± 19% | |
podocyte | 5 studies | 65% ± 29% | |
type I pneumocyte | 5 studies | 45% ± 5% | |
type II pneumocyte | 5 studies | 33% ± 3% | |
hepatocyte | 4 studies | 45% ± 19% | |
granule cell | 4 studies | 78% ± 16% | |
Mueller cell | 4 studies | 84% ± 12% | |
ON-bipolar cell | 4 studies | 70% ± 31% | |
retinal cone cell | 4 studies | 81% ± 15% | |
retinal ganglion cell | 4 studies | 95% ± 3% | |
retinal rod cell | 4 studies | 65% ± 11% | |
ciliated cell | 4 studies | 33% ± 10% | |
hepatic stellate cell | 3 studies | 47% ± 7% | |
differentiation-committed oligodendrocyte precursor | 3 studies | 84% ± 1% | |
GABAergic interneuron | 3 studies | 91% ± 8% | |
glial cell | 3 studies | 59% ± 19% | |
macrophage | 3 studies | 42% ± 16% | |
progenitor cell | 3 studies | 52% ± 17% | |
GABAergic amacrine cell | 3 studies | 93% ± 6% | |
OFF-bipolar cell | 3 studies | 78% ± 4% | |
glycinergic amacrine cell | 3 studies | 86% ± 9% | |
rod bipolar cell | 3 studies | 60% ± 30% | |
endothelial cell of vascular tree | 3 studies | 28% ± 8% | |
retinal pigment epithelial cell | 3 studies | 65% ± 21% | |
connective tissue cell | 3 studies | 52% ± 25% | |
ependymal cell | 3 studies | 85% ± 2% | |
capillary endothelial cell | 3 studies | 25% ± 1% | |
club cell | 3 studies | 36% ± 10% | |
myofibroblast cell | 3 studies | 42% ± 18% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 3981.55 | 2642 / 2642 | 99% | 9.11 | 701 / 705 |
adrenal gland | 99% | 961.86 | 256 / 258 | 85% | 3.02 | 196 / 230 |
prostate | 98% | 1496.93 | 240 / 245 | 72% | 1.29 | 360 / 502 |
thymus | 100% | 1386.62 | 650 / 653 | 67% | 1.22 | 405 / 605 |
kidney | 99% | 1075.34 | 88 / 89 | 40% | 0.72 | 361 / 901 |
breast | 98% | 962.48 | 451 / 459 | 40% | 1.24 | 444 / 1118 |
ovary | 100% | 1427.01 | 180 / 180 | 21% | 0.33 | 89 / 430 |
uterus | 98% | 1143.19 | 167 / 170 | 12% | 0.22 | 57 / 459 |
lung | 88% | 639.14 | 511 / 578 | 20% | 0.35 | 227 / 1155 |
bladder | 100% | 1178.57 | 21 / 21 | 8% | 0.13 | 40 / 504 |
blood vessel | 100% | 2794.09 | 1333 / 1335 | 0% | 0 | 0 / 0 |
adipose | 99% | 1028.75 | 1191 / 1204 | 0% | 0 | 0 / 0 |
skin | 45% | 289.79 | 812 / 1809 | 51% | 1.04 | 241 / 472 |
intestine | 83% | 773.20 | 804 / 966 | 5% | 0.08 | 24 / 527 |
esophagus | 68% | 832.00 | 979 / 1445 | 14% | 0.21 | 25 / 183 |
spleen | 65% | 395.39 | 157 / 241 | 0% | 0 | 0 / 0 |
stomach | 47% | 408.67 | 168 / 359 | 6% | 0.12 | 17 / 286 |
heart | 49% | 282.86 | 420 / 861 | 0% | 0 | 0 / 0 |
pancreas | 12% | 63.29 | 40 / 328 | 31% | 0.60 | 56 / 178 |
eye | 0% | 0 | 0 / 0 | 34% | 0.51 | 27 / 80 |
muscle | 12% | 59.72 | 93 / 803 | 0% | 0 | 0 / 0 |
liver | 2% | 7.70 | 4 / 226 | 1% | 0.03 | 6 / 406 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0008285 | Biological process | negative regulation of cell population proliferation |
GO_0010976 | Biological process | positive regulation of neuron projection development |
GO_0003402 | Biological process | planar cell polarity pathway involved in axis elongation |
GO_0007165 | Biological process | signal transduction |
GO_0038180 | Biological process | nerve growth factor signaling pathway |
GO_0032926 | Biological process | negative regulation of activin receptor signaling pathway |
GO_0002092 | Biological process | positive regulation of receptor internalization |
GO_0043113 | Biological process | receptor clustering |
GO_0051898 | Biological process | negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
GO_0060395 | Biological process | SMAD protein signal transduction |
GO_1990090 | Biological process | cellular response to nerve growth factor stimulus |
GO_0072015 | Biological process | podocyte development |
GO_0030336 | Biological process | negative regulation of cell migration |
GO_0072583 | Biological process | clathrin-dependent endocytosis |
GO_0032516 | Biological process | positive regulation of phosphoprotein phosphatase activity |
GO_0007399 | Biological process | nervous system development |
GO_0036057 | Cellular component | slit diaphragm |
GO_0005886 | Cellular component | plasma membrane |
GO_0001750 | Cellular component | photoreceptor outer segment |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0005813 | Cellular component | centrosome |
GO_0032991 | Cellular component | protein-containing complex |
GO_0001917 | Cellular component | photoreceptor inner segment |
GO_0030425 | Cellular component | dendrite |
GO_0005814 | Cellular component | centriole |
GO_0005911 | Cellular component | cell-cell junction |
GO_0045202 | Cellular component | synapse |
GO_0014069 | Cellular component | postsynaptic density |
GO_0005770 | Cellular component | late endosome |
GO_0005737 | Cellular component | cytoplasm |
GO_0097546 | Cellular component | ciliary base |
GO_0005923 | Cellular component | bicellular tight junction |
GO_0005634 | Cellular component | nucleus |
GO_0070699 | Molecular function | type II activin receptor binding |
GO_0046332 | Molecular function | SMAD binding |
GO_0019902 | Molecular function | phosphatase binding |
GO_0031697 | Molecular function | beta-1 adrenergic receptor binding |
GO_0030159 | Molecular function | signaling receptor complex adaptor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | MAGI2 |
Protein name | Membrane associated guanylate kinase, WW and PDZ domain containing 2 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Atrophin-1-interacting protein 1) (AIP-1) (Atrophin-1-interacting protein A) (Membrane-associated guanylate kinase inverted 2) (MAGI-2) |
Synonyms | hCG_40263 AIP1 KIAA0705 ACVRINP1 |
Description | FUNCTION: Seems to act as a scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins (By similarity). Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth (By similarity). May play a role in regulating activin-mediated signaling in neuronal cells (By similarity). Enhances the ability of PTEN to suppress AKT1 activation . Plays a role in receptor-mediated clathrin-dependent endocytosis which is required for ciliogenesis (By similarity). . |
Accessions | ENST00000628361.1 A0A0D9SGF8 A0A0D9SF86 A0A0D9SFY9 ENST00000419488.5 [Q86UL8-2] ENST00000519748.5 A0A1B0GVS6 ENST00000524268.1 ENST00000522342.3 ENST00000637585.1 ENST00000637282.1 A0A1B0GVS0 ENST00000522391.3 A0A0D9SEY4 ENST00000636178.1 A0A1B0GUF0 ENST00000636717.1 ENST00000637441.1 ENST00000629359.2 A0A0D9SFP3 A0A0U1RRH4 ENST00000634996.1 Q86UL8 A0A1B0GTH8 A0A1B0GUI9 A0A0D9SGF2 A0A0D9SET0 E7EWI0 ENST00000630991.2 ENST00000628781.1 A0A1B0GTC0 ENST00000637486.1 ENST00000354212.9 [Q86UL8-1] ENST00000636039.1 ENST00000626691.2 A0A0D9SEZ7 A0A1B0GUV4 |