SHC3 | OmnibusX

Name	Number of supported studies	Average coverage
oligodendrocyte precursor cell	14 studies	54% ± 21%	Explore
glutamatergic neuron	9 studies	51% ± 24%	Explore
GABAergic neuron	8 studies	44% ± 27%	Explore
astrocyte	6 studies	25% ± 13%	Explore
interneuron	6 studies	41% ± 24%	Explore
type II pneumocyte	5 studies	30% ± 9%	Explore
neuron	4 studies	25% ± 6%	Explore

Name	Number of supported studies	Average coverage
brain	11 studies	35% ± 24%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	99%	7162.34	2613 / 2642	100%	44.60	703 / 705
adrenal gland	100%	4020.68	258 / 258	90%	8.37	206 / 230
lung	83%	1264.68	482 / 578	57%	2.06	664 / 1155
bladder	71%	465.62	15 / 21	55%	1.95	276 / 504
pancreas	77%	825.32	254 / 328	41%	0.97	73 / 178
skin	85%	1148.23	1529 / 1809	25%	1.83	118 / 472
esophagus	65%	440.20	933 / 1445	39%	1.08	72 / 183
breast	68%	791.88	314 / 459	34%	0.77	378 / 1118
ureter	0%	0	0 / 0	100%	5.07	1 / 1
thymus	22%	115.41	142 / 653	75%	3.28	455 / 605
intestine	62%	506.46	599 / 966	34%	1.05	179 / 527
uterus	51%	539.83	87 / 170	41%	1.92	188 / 459
stomach	30%	232.71	109 / 359	37%	1.37	107 / 286
prostate	56%	383.56	138 / 245	7%	0.12	35 / 502
kidney	42%	271.92	37 / 89	12%	0.48	105 / 901
adipose	37%	247.44	440 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	24%	0.56	11 / 45
blood vessel	18%	107.69	240 / 1335	0%	0	0 / 0
heart	17%	98.54	147 / 861	0%	0	0 / 0
ovary	7%	55.27	12 / 180	9%	0.20	37 / 430
liver	0%	0	0 / 226	7%	0.12	29 / 406
lymph node	0%	0	0 / 0	7%	0.10	2 / 29
eye	0%	0	0 / 0	4%	0.09	3 / 80
spleen	0%	1.52	1 / 241	0%	0	0 / 0
peripheral blood	0%	0.62	1 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0007173	Biological process	epidermal growth factor receptor signaling pathway
GO_0035556	Biological process	intracellular signal transduction
GO_0007169	Biological process	cell surface receptor protein tyrosine kinase signaling pathway
GO_0007417	Biological process	central nervous system development
GO_0005575	Cellular component	cellular_component
GO_0005829	Cellular component	cytosol
GO_0005886	Cellular component	plasma membrane
GO_0005515	Molecular function	protein binding
GO_0001784	Molecular function	phosphotyrosine residue binding
GO_0030971	Molecular function	receptor tyrosine kinase binding

Gene name	SHC3
Protein name	SHC adaptor protein 3 SHC-transforming protein 3 (Neuronal Shc) (N-Shc) (Protein Rai) (SHC-transforming protein C) (Src homology 2 domain-containing-transforming protein C3) (SH2 domain protein C3)
Synonyms	NSHC SHCC
Description	FUNCTION: Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
Accessions	Q5T7I8 ENST00000375831.1 Q92529 ENST00000375835.9 [Q92529-1]

SHC3 report