CASS4 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of CASS4 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	1655.67	578 / 578	79%	3.26	912 / 1155
brain	87%	83.57	2294 / 2642	80%	2.14	567 / 705
ovary	96%	179.96	173 / 180	59%	1.32	255 / 430
breast	92%	85.50	420 / 459	54%	1.21	607 / 1118
kidney	71%	65.33	63 / 89	66%	2.34	594 / 901
intestine	95%	104.63	918 / 966	37%	0.79	194 / 527
stomach	75%	51.73	270 / 359	53%	1.22	152 / 286
liver	94%	84.35	213 / 226	28%	0.50	112 / 406
prostate	90%	78.53	221 / 245	31%	0.50	154 / 502
esophagus	85%	101.94	1234 / 1445	34%	0.66	62 / 183
skin	73%	56.23	1324 / 1809	40%	1.07	187 / 472
adrenal gland	92%	96.88	238 / 258	12%	0.22	27 / 230
spleen	100%	536.81	241 / 241	0%	0	0 / 0
bladder	62%	50.05	13 / 21	37%	0.88	187 / 504
thymus	64%	44.24	419 / 653	34%	0.67	203 / 605
uterus	71%	44.26	120 / 170	25%	0.63	116 / 459
adipose	96%	143.22	1154 / 1204	0%	0	0 / 0
pancreas	43%	23.47	141 / 328	52%	1.23	92 / 178
peripheral blood	91%	587.18	841 / 929	0%	0	0 / 0
blood vessel	86%	93.20	1143 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	72%	2.89	21 / 29
heart	58%	37.05	503 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	51%	1.15	23 / 45
muscle	26%	12.78	210 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_1900026	Biological process	positive regulation of substrate adhesion-dependent cell spreading
GO_0061098	Biological process	positive regulation of protein tyrosine kinase activity
GO_0051897	Biological process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0030335	Biological process	positive regulation of cell migration
GO_0007155	Biological process	cell adhesion
GO_0007169	Biological process	cell surface receptor protein tyrosine kinase signaling pathway
GO_0016477	Biological process	cell migration
GO_0005856	Cellular component	cytoskeleton
GO_0005886	Cellular component	plasma membrane
GO_0005737	Cellular component	cytoplasm
GO_0005925	Cellular component	focal adhesion
GO_1990782	Molecular function	protein tyrosine kinase binding

Gene name	CASS4
Protein name	Cas scaffold protein family member 4 (cDNA FLJ53493, highly similar to HEF-like protein) Cas scaffolding protein family member 4 (HEF-like protein) (HEF1-EFS-p130Cas-like protein) (HEPL)
Synonyms	HEFL C20orf32
Description	FUNCTION: Docking protein that plays a role in tyrosine kinase-based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading. .
Accessions	ENST00000434344.2 [Q9NQ75-3] ENST00000360314.7 [Q9NQ75-1] ENST00000679887.1 [Q9NQ75-1] Q9NQ75 B4DII4 ENST00000679529.1

CASS4 report