Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 26 studies | 30% ± 14% | |
non-classical monocyte | 14 studies | 26% ± 13% | |
monocyte | 12 studies | 26% ± 12% | |
classical monocyte | 12 studies | 22% ± 9% | |
endothelial cell | 12 studies | 22% ± 5% | |
plasmacytoid dendritic cell | 12 studies | 27% ± 11% | |
myeloid cell | 12 studies | 35% ± 11% | |
microglial cell | 10 studies | 31% ± 13% | |
dendritic cell | 9 studies | 33% ± 18% | |
conventional dendritic cell | 8 studies | 29% ± 14% | |
mast cell | 8 studies | 24% ± 6% | |
mononuclear phagocyte | 7 studies | 24% ± 9% | |
endothelial cell of lymphatic vessel | 4 studies | 28% ± 5% | |
tissue-resident macrophage | 3 studies | 34% ± 13% | |
leukocyte | 3 studies | 20% ± 4% | |
alveolar macrophage | 3 studies | 31% ± 12% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 3 studies | 25% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 3684.47 | 459 / 459 | 98% | 22.03 | 1095 / 1118 |
thymus | 100% | 3214.87 | 653 / 653 | 96% | 19.18 | 582 / 605 |
lung | 100% | 5483.55 | 578 / 578 | 95% | 19.42 | 1102 / 1155 |
intestine | 100% | 2579.16 | 965 / 966 | 95% | 19.34 | 503 / 527 |
kidney | 100% | 2522.78 | 89 / 89 | 95% | 37.52 | 857 / 901 |
pancreas | 97% | 1144.10 | 317 / 328 | 97% | 21.58 | 173 / 178 |
adrenal gland | 100% | 2531.03 | 258 / 258 | 93% | 29.37 | 213 / 230 |
brain | 92% | 1133.59 | 2439 / 2642 | 99% | 19.80 | 696 / 705 |
esophagus | 91% | 1625.62 | 1318 / 1445 | 98% | 26.16 | 180 / 183 |
stomach | 91% | 1293.83 | 325 / 359 | 98% | 25.12 | 281 / 286 |
liver | 100% | 1791.94 | 226 / 226 | 88% | 14.87 | 357 / 406 |
skin | 88% | 2538.02 | 1583 / 1809 | 97% | 52.06 | 457 / 472 |
uterus | 100% | 2315.09 | 170 / 170 | 83% | 11.27 | 379 / 459 |
ovary | 94% | 1404.66 | 170 / 180 | 88% | 14.18 | 378 / 430 |
bladder | 100% | 2319.62 | 21 / 21 | 82% | 13.61 | 415 / 504 |
prostate | 100% | 2082.15 | 244 / 245 | 80% | 8.80 | 402 / 502 |
adipose | 100% | 4938.70 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 8387.76 | 241 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2762.87 | 1332 / 1335 | 0% | 0 | 0 / 0 |
heart | 100% | 3356.79 | 859 / 861 | 0% | 0 | 0 / 0 |
muscle | 98% | 1428.81 | 785 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 97% | 3526.02 | 899 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 97% | 28.42 | 28 / 29 |
tonsil | 0% | 0 | 0 / 0 | 89% | 18.18 | 40 / 45 |
eye | 0% | 0 | 0 / 0 | 79% | 9.16 | 63 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0001780 | Biological process | neutrophil homeostasis |
GO_0008285 | Biological process | negative regulation of cell population proliferation |
GO_0048821 | Biological process | erythrocyte development |
GO_0036016 | Biological process | cellular response to interleukin-3 |
GO_0007169 | Biological process | cell surface receptor protein tyrosine kinase signaling pathway |
GO_0046426 | Biological process | negative regulation of receptor signaling pathway via JAK-STAT |
GO_0070100 | Biological process | negative regulation of chemokine-mediated signaling pathway |
GO_0038163 | Biological process | thrombopoietin-mediated signaling pathway |
GO_0090331 | Biological process | negative regulation of platelet aggregation |
GO_1900235 | Biological process | negative regulation of Kit signaling pathway |
GO_0035855 | Biological process | megakaryocyte development |
GO_0035702 | Biological process | monocyte homeostasis |
GO_0060761 | Biological process | negative regulation of response to cytokine stimulus |
GO_0051898 | Biological process | negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
GO_0060218 | Biological process | hematopoietic stem cell differentiation |
GO_1904893 | Biological process | negative regulation of receptor signaling pathway via STAT |
GO_0035556 | Biological process | intracellular signal transduction |
GO_0043409 | Biological process | negative regulation of MAPK cascade |
GO_1990869 | Biological process | cellular response to chemokine |
GO_0035162 | Biological process | embryonic hemopoiesis |
GO_0005886 | Cellular component | plasma membrane |
GO_0005829 | Cellular component | cytosol |
GO_1990782 | Molecular function | protein tyrosine kinase binding |
GO_0005068 | Molecular function | transmembrane receptor protein tyrosine kinase adaptor activity |
GO_0030159 | Molecular function | signaling receptor complex adaptor activity |
GO_0005173 | Molecular function | stem cell factor receptor binding |
GO_0005515 | Molecular function | protein binding |
Gene name | SH2B3 |
Protein name | SH2B3 protein SH2B adaptor protein 3 Truncated SH2B3 SH2B adapter protein 3 (Lymphocyte adapter protein) (Lymphocyte-specific adapter protein Lnk) (Signal transduction protein Lnk) |
Synonyms | LNK |
Description | FUNCTION: Links T-cell receptor activation signal to phospholipase C-gamma-1, GRB2 and phosphatidylinositol 3-kinase. . |
Accessions | Q9UQQ2 R4GN84 F5GYM4 ENST00000538307.1 ENST00000341259.7 Q96BA5 ENST00000550925.2 A0A7D5B980 |