EFS | OmnibusX

Name	Number of supported studies	Average coverage
oligodendrocyte	5 studies	23% ± 5%	Explore
oligodendrocyte precursor cell	3 studies	23% ± 3%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of EFS at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	99%	2543.35	2607 / 2642	99%	89.43	701 / 705
breast	100%	3146.89	458 / 459	88%	36.90	985 / 1118
uterus	100%	5602.26	170 / 170	86%	45.57	395 / 459
prostate	100%	4776.64	245 / 245	75%	19.85	374 / 502
bladder	100%	3156.76	21 / 21	68%	32.67	345 / 504
thymus	99%	2413.09	648 / 653	67%	13.01	406 / 605
lung	97%	1572.34	563 / 578	68%	28.60	786 / 1155
esophagus	100%	3537.84	1445 / 1445	58%	34.79	107 / 183
ovary	100%	5150.00	180 / 180	52%	14.69	224 / 430
skin	94%	5034.15	1693 / 1809	34%	14.14	159 / 472
tonsil	0%	0	0 / 0	100%	51.88	45 / 45
blood vessel	100%	3175.78	1333 / 1335	0%	0	0 / 0
adipose	100%	2320.42	1201 / 1204	0%	0	0 / 0
intestine	83%	2108.67	799 / 966	10%	1.81	53 / 527
adrenal gland	29%	391.34	75 / 258	57%	43.92	132 / 230
stomach	62%	1163.74	224 / 359	12%	2.29	35 / 286
spleen	74%	836.77	179 / 241	0%	0	0 / 0
kidney	58%	699.10	52 / 89	15%	2.85	136 / 901
heart	62%	812.90	531 / 861	0%	0	0 / 0
pancreas	1%	7.99	4 / 328	53%	9.41	94 / 178
eye	0%	0	0 / 0	44%	9.49	35 / 80
muscle	5%	46.96	41 / 803	0%	0	0 / 0
liver	1%	9.60	2 / 226	2%	0.28	8 / 406
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0035556	Biological process	intracellular signal transduction
GO_0007155	Biological process	cell adhesion
GO_0007169	Biological process	cell surface receptor protein tyrosine kinase signaling pathway
GO_0016477	Biological process	cell migration
GO_0005886	Cellular component	plasma membrane
GO_0005737	Cellular component	cytoplasm
GO_0005925	Cellular component	focal adhesion
GO_0019904	Molecular function	protein domain specific binding
GO_0005515	Molecular function	protein binding
GO_0017124	Molecular function	SH3 domain binding

Gene name	EFS
Protein name	Embryonal Fyn-associated substrate (hEFS) (Cas scaffolding protein family member 3)
Synonyms	CASS3
Description	FUNCTION: Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES (By similarity). .
Accessions	ENST00000216733.8 [O43281-1] ENST00000351354.3 [O43281-2] ENST00000429593.6 [O43281-3] O43281

EFS report