LCP2 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
macrophage	35 studies	35% ± 12%	Explore
natural killer cell	32 studies	29% ± 10%	Explore
CD8-positive, alpha-beta T cell	31 studies	35% ± 13%	Explore
CD4-positive, alpha-beta T cell	29 studies	31% ± 10%	Explore
regulatory T cell	25 studies	40% ± 14%	Explore
classical monocyte	24 studies	32% ± 8%	Explore
mast cell	23 studies	29% ± 10%	Explore
T cell	22 studies	32% ± 11%	Explore
non-classical monocyte	21 studies	44% ± 12%	Explore
monocyte	19 studies	36% ± 10%	Explore
conventional dendritic cell	18 studies	32% ± 14%	Explore
mature NK T cell	17 studies	33% ± 16%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	35% ± 13%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	35% ± 11%	Explore
gamma-delta T cell	15 studies	39% ± 10%	Explore
myeloid cell	15 studies	33% ± 11%	Explore
dendritic cell	14 studies	30% ± 10%	Explore
mucosal invariant T cell	14 studies	37% ± 14%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	13 studies	32% ± 10%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	31% ± 9%	Explore
microglial cell	12 studies	26% ± 11%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	35% ± 10%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	39% ± 9%	Explore
neutrophil	10 studies	37% ± 14%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	37% ± 10%	Explore
T follicular helper cell	7 studies	36% ± 11%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	40% ± 13%	Explore
leukocyte	6 studies	27% ± 7%	Explore
mononuclear phagocyte	6 studies	29% ± 8%	Explore
hematopoietic stem cell	6 studies	23% ± 5%	Explore
exhausted T cell	5 studies	49% ± 8%	Explore
lymphocyte	5 studies	39% ± 11%	Explore
T-helper 17 cell	5 studies	34% ± 19%	Explore
innate lymphoid cell	5 studies	29% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	35% ± 11%	Explore
hematopoietic precursor cell	4 studies	32% ± 15%	Explore
platelet	4 studies	20% ± 3%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	47% ± 7%	Explore
intermediate monocyte	4 studies	44% ± 20%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	37% ± 5%	Explore
alveolar macrophage	4 studies	30% ± 10%	Explore
megakaryocyte	3 studies	47% ± 17%	Explore
tissue-resident macrophage	3 studies	42% ± 11%	Explore
granulocyte	3 studies	34% ± 21%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	40% ± 16%	Explore
group 3 innate lymphoid cell	3 studies	38% ± 3%	Explore
T-helper 1 cell	3 studies	40% ± 11%	Explore
double negative thymocyte	3 studies	38% ± 9%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	16 studies	28% ± 8%	Explore
lung	4 studies	23% ± 9%	Explore
bone marrow	3 studies	25% ± 8%	Explore
lymph node	3 studies	29% ± 8%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	4280.74	578 / 578	96%	16.22	1111 / 1155
breast	98%	1251.55	450 / 459	96%	13.41	1076 / 1118
thymus	91%	813.37	596 / 653	91%	13.77	549 / 605
stomach	90%	737.29	323 / 359	86%	13.22	246 / 286
intestine	91%	1252.63	879 / 966	83%	9.63	435 / 527
uterus	89%	593.25	152 / 170	80%	8.33	365 / 459
prostate	95%	995.05	233 / 245	69%	4.62	344 / 502
kidney	75%	617.06	67 / 89	88%	16.69	789 / 901
bladder	90%	955.62	19 / 21	69%	8.26	349 / 504
esophagus	71%	473.34	1027 / 1445	86%	9.47	158 / 183
adrenal gland	93%	861.86	239 / 258	53%	3.94	123 / 230
brain	53%	366.39	1411 / 2642	92%	11.35	646 / 705
skin	47%	310.22	852 / 1809	88%	21.51	413 / 472
liver	72%	486.49	163 / 226	57%	4.52	233 / 406
ovary	37%	217.49	66 / 180	80%	7.97	343 / 430
pancreas	22%	138.30	73 / 328	90%	11.85	161 / 178
lymph node	0%	0	0 / 0	100%	45.20	29 / 29
peripheral blood	100%	11573.50	929 / 929	0%	0	0 / 0
spleen	100%	8003.21	241 / 241	0%	0	0 / 0
adipose	100%	2282.48	1203 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	91%	15.88	41 / 45
blood vessel	78%	786.55	1041 / 1335	0%	0	0 / 0
heart	54%	331.87	467 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	23%	2.01	18 / 80
muscle	14%	63.55	113 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1