I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 4 studies | 20% ± 4% | |
| epithelial cell | 4 studies | 33% ± 4% | |
| type I pneumocyte | 4 studies | 19% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 4 studies | 20% ± 4% | |
| epithelial cell | 4 studies | 33% ± 4% | |
| type I pneumocyte | 4 studies | 19% ± 2% |
Insufficient scRNA-seq data for expression of CNKSR1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 100% | 1565.38 | 328 / 328 | 98% | 27.81 | 175 / 178 |
| thymus | 100% | 2945.60 | 652 / 653 | 98% | 33.49 | 594 / 605 |
| lung | 97% | 1142.94 | 560 / 578 | 98% | 27.17 | 1132 / 1155 |
| prostate | 93% | 1926.69 | 229 / 245 | 99% | 26.86 | 498 / 502 |
| ovary | 78% | 441.02 | 141 / 180 | 99% | 34.07 | 426 / 430 |
| stomach | 78% | 1178.69 | 280 / 359 | 97% | 26.02 | 276 / 286 |
| bladder | 71% | 772.14 | 15 / 21 | 95% | 35.50 | 481 / 504 |
| breast | 61% | 1150.71 | 282 / 459 | 97% | 28.26 | 1087 / 1118 |
| intestine | 54% | 986.34 | 526 / 966 | 98% | 28.75 | 516 / 527 |
| uterus | 61% | 411.66 | 103 / 170 | 90% | 29.39 | 414 / 459 |
| esophagus | 44% | 1046.85 | 633 / 1445 | 98% | 26.37 | 179 / 183 |
| kidney | 99% | 954.03 | 88 / 89 | 15% | 1.85 | 134 / 901 |
| muscle | 100% | 4022.91 | 803 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 25.92 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 11.78 | 1 / 1 |
| skin | 72% | 1394.86 | 1305 / 1809 | 6% | 0.58 | 29 / 472 |
| brain | 54% | 358.55 | 1434 / 2642 | 11% | 0.84 | 80 / 705 |
| spleen | 46% | 292.83 | 110 / 241 | 0% | 0 | 0 / 0 |
| liver | 17% | 76.53 | 38 / 226 | 18% | 2.99 | 73 / 406 |
| peripheral blood | 8% | 35.01 | 72 / 929 | 0% | 0 | 0 / 0 |
| heart | 7% | 25.75 | 60 / 861 | 0% | 0 | 0 / 0 |
| adipose | 6% | 23.68 | 71 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 5% | 18.10 | 62 / 1335 | 0% | 0 | 0 / 0 |
| adrenal gland | 1% | 2.62 | 2 / 258 | 1% | 0.19 | 2 / 230 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007169 | Biological process | cell surface receptor protein tyrosine kinase signaling pathway |
| GO_0005911 | Cellular component | cell-cell junction |
| GO_0005938 | Cellular component | cell cortex |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0030674 | Molecular function | protein-macromolecule adaptor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CNKSR1 |
| Protein name | Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR 1) (CNK homolog protein 1) (CNK1) (hCNK1) (Connector enhancer of KSR-like) Connector enhancer of kinase suppressor of Ras 1 variant (Connector enhancer of kinase suppressor of Ras 1, isoform CRA_b) Connector enhancer of kinase suppressor of Ras 1 |
| Synonyms | hCG_40691 CNK1 |
| Description | FUNCTION: May function as an adapter protein or regulator of Ras signaling pathways. |
| Accessions | Q53GM7 ENST00000528281.5 B4DXN4 ENST00000481077.6 ENST00000361530.11 [Q969H4-2] E9PIE0 ENST00000525687.5 ENST00000531191.5 ENST00000482227.5 ENST00000374253.9 [Q969H4-1] H0YDP5 E9PS82 Q969H4 G3V160 |
