Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 11 studies | 38% ± 16% | |
glutamatergic neuron | 8 studies | 41% ± 17% | |
interneuron | 5 studies | 39% ± 13% | |
retinal ganglion cell | 5 studies | 45% ± 21% | |
Mueller cell | 5 studies | 23% ± 5% | |
GABAergic neuron | 5 studies | 41% ± 19% | |
oligodendrocyte precursor cell | 5 studies | 29% ± 11% | |
amacrine cell | 4 studies | 40% ± 30% | |
retina horizontal cell | 4 studies | 18% ± 2% | |
fibroblast | 3 studies | 23% ± 8% | |
ependymal cell | 3 studies | 36% ± 7% | |
neuron | 3 studies | 25% ± 2% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 8 studies | 30% ± 14% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 91% | 769.00 | 2409 / 2642 | 99% | 46.33 | 696 / 705 |
kidney | 81% | 221.88 | 72 / 89 | 55% | 8.60 | 496 / 901 |
thymus | 99% | 392.23 | 647 / 653 | 37% | 3.34 | 223 / 605 |
ovary | 33% | 63.08 | 60 / 180 | 97% | 85.49 | 419 / 430 |
breast | 83% | 186.95 | 381 / 459 | 36% | 3.65 | 403 / 1118 |
muscle | 100% | 917.11 | 800 / 803 | 0% | 0 | 0 / 0 |
heart | 92% | 508.81 | 792 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 91% | 395.95 | 1215 / 1335 | 0% | 0 | 0 / 0 |
adipose | 84% | 206.22 | 1017 / 1204 | 0% | 0 | 0 / 0 |
bladder | 71% | 180.57 | 15 / 21 | 11% | 1.03 | 53 / 504 |
pancreas | 5% | 8.11 | 15 / 328 | 76% | 10.90 | 135 / 178 |
adrenal gland | 22% | 33.73 | 58 / 258 | 58% | 27.94 | 133 / 230 |
uterus | 58% | 104.56 | 98 / 170 | 20% | 3.35 | 92 / 459 |
eye | 0% | 0 | 0 / 0 | 66% | 10.54 | 53 / 80 |
intestine | 48% | 84.58 | 465 / 966 | 12% | 1.08 | 64 / 527 |
skin | 26% | 49.00 | 474 / 1809 | 29% | 6.45 | 135 / 472 |
lung | 31% | 65.58 | 181 / 578 | 19% | 2.13 | 225 / 1155 |
prostate | 39% | 67.54 | 96 / 245 | 2% | 0.09 | 8 / 502 |
stomach | 23% | 39.93 | 84 / 359 | 17% | 1.22 | 49 / 286 |
esophagus | 33% | 58.01 | 474 / 1445 | 4% | 0.21 | 7 / 183 |
liver | 5% | 5.88 | 11 / 226 | 5% | 0.49 | 22 / 406 |
lymph node | 0% | 0 | 0 / 0 | 7% | 0.73 | 2 / 29 |
tonsil | 0% | 0 | 0 / 0 | 7% | 0.31 | 3 / 45 |
spleen | 3% | 4.18 | 7 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 1% | 0.76 | 5 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0051386 | Biological process | regulation of neurotrophin TRK receptor signaling pathway |
GO_0030182 | Biological process | neuron differentiation |
GO_0007265 | Biological process | Ras protein signal transduction |
GO_0007169 | Biological process | cell surface receptor protein tyrosine kinase signaling pathway |
GO_0043410 | Biological process | positive regulation of MAPK cascade |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
Gene name | DOK5 |
Protein name | Docking protein 5 (Downstream of tyrosine kinase 5) (Insulin receptor substrate 6) (IRS-6) (IRS6) |
Synonyms | C20orf180 |
Description | FUNCTION: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation. |
Accessions | ENST00000262593.10 [Q9P104-1] ENST00000395939.5 [Q9P104-2] Q9P104 |