Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| smooth muscle cell | 17 studies | 28% ± 8% | |
| pericyte | 17 studies | 27% ± 9% | |
| astrocyte | 12 studies | 32% ± 13% | |
| adipocyte | 9 studies | 66% ± 12% | |
| endothelial cell | 5 studies | 22% ± 4% | |
| cardiac muscle cell | 5 studies | 36% ± 8% | |
| muscle cell | 4 studies | 32% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 94% | 7210.26 | 613 / 653 | 92% | 16.97 | 557 / 605 |
| prostate | 90% | 10466.29 | 221 / 245 | 95% | 20.56 | 476 / 502 |
| brain | 57% | 3170.78 | 1517 / 2642 | 100% | 70.82 | 705 / 705 |
| breast | 97% | 20177.14 | 447 / 459 | 58% | 7.30 | 651 / 1118 |
| bladder | 90% | 13547.33 | 19 / 21 | 56% | 8.01 | 284 / 504 |
| intestine | 79% | 17128.18 | 766 / 966 | 67% | 7.23 | 354 / 527 |
| uterus | 92% | 11362.65 | 157 / 170 | 51% | 15.21 | 233 / 459 |
| esophagus | 74% | 17192.26 | 1065 / 1445 | 60% | 7.41 | 109 / 183 |
| kidney | 36% | 2087.88 | 32 / 89 | 95% | 22.34 | 857 / 901 |
| ovary | 45% | 3904.32 | 81 / 180 | 83% | 12.55 | 358 / 430 |
| skin | 33% | 1932.01 | 602 / 1809 | 89% | 60.68 | 421 / 472 |
| stomach | 47% | 7936.40 | 170 / 359 | 74% | 12.00 | 213 / 286 |
| lung | 50% | 2987.49 | 290 / 578 | 51% | 5.76 | 585 / 1155 |
| adrenal gland | 19% | 890.51 | 50 / 258 | 81% | 13.11 | 187 / 230 |
| blood vessel | 100% | 35228.06 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 4.12 | 1 / 1 |
| adipose | 100% | 29332.97 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 99% | 20420.73 | 797 / 803 | 0% | 0 | 0 / 0 |
| heart | 98% | 28840.55 | 848 / 861 | 0% | 0 | 0 / 0 |
| pancreas | 2% | 57.60 | 5 / 328 | 93% | 14.14 | 165 / 178 |
| liver | 2% | 85.63 | 5 / 226 | 87% | 10.42 | 354 / 406 |
| tonsil | 0% | 0 | 0 / 0 | 40% | 7.54 | 18 / 45 |
| spleen | 35% | 1861.35 | 84 / 241 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 24% | 1.68 | 7 / 29 |
| eye | 0% | 0 | 0 / 0 | 15% | 1.16 | 12 / 80 |
| peripheral blood | 12% | 922.63 | 116 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0008360 | Biological process | regulation of cell shape |
| GO_0035987 | Biological process | endodermal cell differentiation |
| GO_0007229 | Biological process | integrin-mediated signaling pathway |
| GO_0033627 | Biological process | cell adhesion mediated by integrin |
| GO_0034113 | Biological process | heterotypic cell-cell adhesion |
| GO_0098609 | Biological process | cell-cell adhesion |
| GO_0050900 | Biological process | leukocyte migration |
| GO_0007517 | Biological process | muscle organ development |
| GO_0007160 | Biological process | cell-matrix adhesion |
| GO_0009986 | Cellular component | cell surface |
| GO_0008305 | Cellular component | integrin complex |
| GO_0009897 | Cellular component | external side of plasma membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005515 | Molecular function | protein binding |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0005178 | Molecular function | integrin binding |
| Gene name | ITGA7 |
| Protein name | ITGA7 variant protein Integrin subunit alpha 7 Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form] |
| Synonyms | UNQ406/PRO768 protein variant |
| Description | FUNCTION: Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as a Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells. . |
| Accessions | ENST00000554724.5 A0A8I5QJA5 ENST00000686981.1 ENST00000554327.6 A0A8I5KXI3 G3V2I4 G3V2C6 H0YJ98 ENST00000556273.5 A0A8I5KSX0 ENST00000347027.10 H0YJ26 ENST00000557257.2 ENST00000691973.1 ENST00000257879.11 [Q13683-7] Q13683 ENST00000557555.3 ENST00000691052.1 ENST00000452168.6 [Q13683-13] ENST00000691846.1 ENST00000555687.5 ENST00000553804.6 [Q13683-3] G3V2Q6 J3KNV4 G3V3L8 ENST00000555728.5 [Q13683-1] ENST00000553893.6 ENST00000555809.1 H0YJS5 Q4LE35 |
