ITGAD report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ITGAD at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ITGAD at tissue level.

III. Associated gene sets

GO_0006955Biological processimmune response
GO_0007229Biological processintegrin-mediated signaling pathway
GO_0033627Biological processcell adhesion mediated by integrin
GO_0034113Biological processheterotypic cell-cell adhesion
GO_0098609Biological processcell-cell adhesion
GO_0007160Biological processcell-matrix adhesion
GO_0009986Cellular componentcell surface
GO_0008305Cellular componentintegrin complex
GO_0009897Cellular componentexternal side of plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0046872Molecular functionmetal ion binding
GO_0005178Molecular functionintegrin binding

IV. Literature review

[source]
Gene nameITGAD
Protein nameIntegrin alpha-D (ADB2) (CD11 antigen-like family member D) (Leukointegrin alpha D) (CD antigen CD11d)
Synonyms
DescriptionFUNCTION: Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. May play a role in the atherosclerotic process such as clearing lipoproteins from plaques and in phagocytosis of blood-borne pathogens, particulate matter, and senescent erythrocytes from the blood.

AccessionsENST00000389202.3
Q13349