Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 38 studies | 33% ± 11% | |
smooth muscle cell | 14 studies | 28% ± 10% | |
capillary endothelial cell | 13 studies | 33% ± 7% | |
endothelial cell of artery | 13 studies | 37% ± 12% | |
vein endothelial cell | 12 studies | 39% ± 17% | |
endothelial cell of vascular tree | 8 studies | 32% ± 13% | |
pericyte | 5 studies | 20% ± 2% | |
cardiac muscle cell | 5 studies | 21% ± 2% | |
glomerular endothelial cell | 3 studies | 43% ± 6% | |
CD4-positive, alpha-beta T cell | 3 studies | 32% ± 4% | |
CD8-positive, alpha-beta T cell | 3 studies | 37% ± 9% | |
immature B cell | 3 studies | 28% ± 11% | |
type I pneumocyte | 3 studies | 19% ± 2% |
Insufficient scRNA-seq data for expression of LIMS2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 98% | 14026.56 | 241 / 245 | 98% | 22.20 | 490 / 502 |
breast | 100% | 9482.84 | 458 / 459 | 84% | 7.36 | 942 / 1118 |
thymus | 89% | 5279.31 | 579 / 653 | 95% | 11.46 | 572 / 605 |
kidney | 93% | 6031.42 | 83 / 89 | 85% | 13.20 | 769 / 901 |
lung | 99% | 11790.11 | 570 / 578 | 73% | 6.51 | 841 / 1155 |
intestine | 88% | 28886.57 | 850 / 966 | 76% | 7.23 | 400 / 527 |
bladder | 95% | 21876.33 | 20 / 21 | 65% | 7.03 | 329 / 504 |
uterus | 99% | 22855.86 | 168 / 170 | 57% | 8.65 | 262 / 459 |
esophagus | 82% | 19523.77 | 1185 / 1445 | 71% | 7.26 | 130 / 183 |
stomach | 58% | 10480.57 | 207 / 359 | 75% | 9.65 | 215 / 286 |
liver | 36% | 1330.30 | 81 / 226 | 92% | 10.88 | 372 / 406 |
ovary | 32% | 1983.39 | 57 / 180 | 89% | 10.65 | 383 / 430 |
brain | 14% | 489.99 | 373 / 2642 | 97% | 45.09 | 684 / 705 |
skin | 36% | 1531.82 | 653 / 1809 | 70% | 10.30 | 331 / 472 |
spleen | 100% | 12058.49 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 3.35 | 1 / 1 |
blood vessel | 100% | 23350.18 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 100% | 13951.98 | 860 / 861 | 0% | 0 | 0 / 0 |
adipose | 98% | 9816.65 | 1183 / 1204 | 0% | 0 | 0 / 0 |
adrenal gland | 22% | 816.44 | 56 / 258 | 75% | 7.51 | 172 / 230 |
eye | 0% | 0 | 0 / 0 | 96% | 34.24 | 77 / 80 |
pancreas | 1% | 33.50 | 3 / 328 | 93% | 12.38 | 165 / 178 |
lymph node | 0% | 0 | 0 / 0 | 69% | 7.14 | 20 / 29 |
tonsil | 0% | 0 | 0 / 0 | 44% | 2.22 | 20 / 45 |
muscle | 21% | 697.88 | 167 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 3.98 | 1 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_1900026 | Biological process | positive regulation of substrate adhesion-dependent cell spreading |
GO_1904055 | Biological process | negative regulation of cholangiocyte proliferation |
GO_2000178 | Biological process | negative regulation of neural precursor cell proliferation |
GO_0007229 | Biological process | integrin-mediated signaling pathway |
GO_0061351 | Biological process | neural precursor cell proliferation |
GO_1990705 | Biological process | cholangiocyte proliferation |
GO_0043066 | Biological process | negative regulation of apoptotic process |
GO_2001046 | Biological process | positive regulation of integrin-mediated signaling pathway |
GO_0098609 | Biological process | cell-cell adhesion |
GO_2000346 | Biological process | negative regulation of hepatocyte proliferation |
GO_0045216 | Biological process | cell-cell junction organization |
GO_0005911 | Cellular component | cell-cell junction |
GO_0005829 | Cellular component | cytosol |
GO_0005886 | Cellular component | plasma membrane |
GO_0005925 | Cellular component | focal adhesion |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0046872 | Molecular function | metal ion binding |
Gene name | LIMS2 |
Protein name | LIMS2 protein LIM zinc finger domain containing 2 Uncharacterized protein LIMS2 LIM and senescent cell antigen-like-containing domain protein 2 (LIM-like protein 2) (Particularly interesting new Cys-His protein 2) (PINCH-2) |
Synonyms | PINCH2 |
Description | FUNCTION: Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. Plays a role in modulating cell spreading and migration. . |
Accessions | H0Y592 ENST00000409808.6 [Q7Z4I7-3] ENST00000409254.1 [Q7Z4I7-4] Q53RZ1 A0PJ44 ENST00000426981.5 F8WEF3 ENST00000413578.5 ENST00000410038.5 [Q7Z4I7-4] Q7Z4I7 ENST00000409455.5 [Q7Z4I7-3] ENST00000545738.6 [Q7Z4I7-5] ENST00000355119.9 [Q7Z4I7-1] ENST00000409754.5 [Q7Z4I7-4] ENST00000410011.5 [Q7Z4I7-3] ENST00000324938.9 [Q7Z4I7-2] ENST00000409286.5 [Q7Z4I7-4] |