LIMS2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of LIMS2 at tissue level.

III. Associated gene sets

GO_1900026Biological processpositive regulation of substrate adhesion-dependent cell spreading
GO_1904055Biological processnegative regulation of cholangiocyte proliferation
GO_2000178Biological processnegative regulation of neural precursor cell proliferation
GO_0007229Biological processintegrin-mediated signaling pathway
GO_0061351Biological processneural precursor cell proliferation
GO_1990705Biological processcholangiocyte proliferation
GO_0043066Biological processnegative regulation of apoptotic process
GO_2001046Biological processpositive regulation of integrin-mediated signaling pathway
GO_0098609Biological processcell-cell adhesion
GO_2000346Biological processnegative regulation of hepatocyte proliferation
GO_0045216Biological processcell-cell junction organization
GO_0005911Cellular componentcell-cell junction
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0005925Cellular componentfocal adhesion
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameLIMS2
Protein nameLIMS2 protein
LIM zinc finger domain containing 2
Uncharacterized protein LIMS2
LIM and senescent cell antigen-like-containing domain protein 2 (LIM-like protein 2) (Particularly interesting new Cys-His protein 2) (PINCH-2)
SynonymsPINCH2
DescriptionFUNCTION: Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. Plays a role in modulating cell spreading and migration. .

AccessionsH0Y592
ENST00000409808.6 [Q7Z4I7-3]
ENST00000409254.1 [Q7Z4I7-4]
Q53RZ1
A0PJ44
ENST00000426981.5
F8WEF3
ENST00000413578.5
ENST00000410038.5 [Q7Z4I7-4]
Q7Z4I7
ENST00000409455.5 [Q7Z4I7-3]
ENST00000545738.6 [Q7Z4I7-5]
ENST00000355119.9 [Q7Z4I7-1]
ENST00000409754.5 [Q7Z4I7-4]
ENST00000410011.5 [Q7Z4I7-3]
ENST00000324938.9 [Q7Z4I7-2]
ENST00000409286.5 [Q7Z4I7-4]